| Tag | Content |
|---|---|
| Uniprot ID | K7BCM9; A0A2J8LPJ7; |
| Entrez ID | 473012 |
| Genbank protein ID | JAA17948.1 |
| Genbank nucleotide ID | XM_016960396.1 |
| Ensembl protein ID | ENSPTRP00000078036 |
| Ensembl nucleotide ID | ENSPTRG00000021229 |
| Gene name | UV excision repair protein RAD23 |
| Gene symbol | RAD23B |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair. |
| Sequence | MQVTLKTLQQ QTFKIDIDPE ETVKALKEKI ESEKGKDAFP VAGQKLIYAG KILNDDTALK 60 EYKIDEKNFV VVMVTKPKAV STPAPATTQQ SAPASTTAVT CSTTTTVAQA PIPVPALAPT 120 STPASITPAS ATASSEPAPA SAAKQEKPAE KPAETPVATS PTATDSTSGD SSRSNLFEDA 180 TSALVTGQSY ENMVTEIMSM GYEREQVIAA LRASFNNPDR AVEYLLMGIP GDRESQAVVD 240 PPQAASTGAP QSSAVAAAAA TTTATTTTTS SGGHPLEFLR NQPQFQQMRQ IIQQNPSLLP 300 ALLQQIGREN PQLLQQISQH QEHFIQMLNE PVQEAGGQGG GGGGGSGGIA EAGSGHMNYI 360 QVTPQEKEAI ERLKALGFPE GLVIQAYFAC EKNENLAANF LLQQNFDED 409 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RAD23B | 530189 | Q29RK4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RAD23B | 481656 | E2R4A5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RAD23B | 102183790 | A0A452FP98 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RAD23B | 5887 | P54727 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Rad23b | 19359 | P54728 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | RAD23B | 473012 | K7BCM9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100153668 | A0A480DNV8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | RAD23B | 100353489 | G1SST9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Rad23b | 298012 | Q4KMA2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | rad23b | 393536 | A0A2R8PYT0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0042025 | host cell nucleus |
| GO:0005654 | nucleoplasm |
| GO:0071942 | XPC complex |
| GO:0003684 | damaged DNA binding |
| GO:0031593 | polyubiquitin modification-dependent protein binding |
| GO:0070628 | proteasome binding |
| GO:0043130 | ubiquitin binding |
| GO:0000715 | nucleotide-excision repair, DNA damage recognition |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process |