Gene: PDGFC

Basic information

Tag Content
Uniprot ID A0A3Q2HV05
Entrez ID 100062015
Genbank protein ID
Genbank nucleotide ID XM_001500645.5
Ensembl protein ID ENSECAP00000037156
Ensembl nucleotide ID ENSECAG00000019512
Gene name Platelet derived growth factor C
Gene symbol PDGFC
Organism Equus caballus
NCBI taxa ID 9796
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLLFGLLLLT SALAGQRHGT QAESNLSSKF QFSSNKEQNG VQDPQHERII TVSTNGSIHS 60
PRFPHTYPRN MDLVWRLVAV EENVWIQLTF DERFGLEDPE DDICKYDFVE VEEPSDGTIL 120
GRWCGSGTVP GKQISKGNQI RIRFVSDEYF PSEPGFCIHY NIVMPQFTEA VSPSALPPSA 180
LPLDLLNNAV TAFSTLEDLI RYLEPDRWQL DLEDLYRPTW QLLGKAFVFG RKSRVVDLNL 240
LKEEVRLYSC TPRNFSVSIR EELKRTDTIF WPGCLLVKRC GGNCACCLHN CNECQCVPSK 300
VTKKYHEVLQ LRPKNGVRGL HKSLTDVALE HHEECDCVCR GNSGG 345

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPDGFC102168934A0A452ET29Capra hircusPredictionMore>>
1:1 orthologPDGFC100062015A0A3Q2HV05Equus caballusPredictionMore>>
1:1 orthologPDGFC56034Q9NRA1Homo sapiensPublicationMore>>
1:1 orthologPdgfc54635Q8CI19CPOE12.5, E13.5Mus musculusPublicationMore>>
1:1 orthologPDGFCH2QQC3Pan troglodytesPredictionMore>>
1:1 orthologA0A481CL63Sus scrofaPredictionMore>>
1:1 orthologPDGFC100350272G1TDA1Oryctolagus cuniculusPredictionMore>>
1:1 orthologPdgfc79429Q9EQX6Rattus norvegicusPredictionMore>>
1:1 orthologpdgfc560564E7FB33Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016020 membrane
GO:0008083 growth factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0048568 embryonic organ development
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0008284 positive regulation of cell population proliferation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0339 Growth factor
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR000859 CUB_dom
IPR029034 Cystine-knot_cytokine
IPR029817 PDGF-C
IPR000072 PDGF/VEGF_dom
IPR035914 Sperma_CUB_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS01180 CUB
PS50278 PDGF_2

Pfam

Pfam ID Pfam Term
PF00431 CUB
PF00341 PDGF