Gene: PDGFC

Basic information

Tag Content
Uniprot ID H2QQC3
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000028405
Ensembl nucleotide ID ENSPTRG00000016546
Gene name Platelet derived growth factor C
Gene symbol PDGFC
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
NFLFSLVSST STLRGVGYGV QDPQHERIIT VSTNGSIHSP RFPHTYPRNT VLVWRLVAVE 60
ENVWIQLTFD ERFGLEDPED DICKYDFVEV EEPSDGTILG RWCGSGTVPG KQISKGNQIR 120
IRFVSDEYFP SEPGFCIHYN IVMPQFTEAV SPSVLPPSAL PLDLLNNAIT AFSTLEDLIR 180
YLEPERWQLD LEDLYKPTWQ LLGKAFVFGR KSRVVDLNLL TEEVRLYSCT PRNFSVSIRE 240
ELKRTDTIFW PGCLLVKRCG GNCACCLHNC NECQCVPSKV TKKYHEVLQL RPKTGVRGLH 300
KSLTDVALEH HEECDCVCRG STGG 324

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPDGFC102168934A0A452ET29Capra hircusPredictionMore>>
1:1 orthologPDGFC100062015A0A3Q2HV05Equus caballusPredictionMore>>
1:1 orthologPDGFC56034Q9NRA1Homo sapiensPublicationMore>>
1:1 orthologPdgfc54635Q8CI19CPOE12.5, E13.5Mus musculusPublicationMore>>
1:1 orthologPDGFCH2QQC3Pan troglodytesPredictionMore>>
1:1 orthologA0A481CL63Sus scrofaPredictionMore>>
1:1 orthologPDGFC100350272G1TDA1Oryctolagus cuniculusPredictionMore>>
1:1 orthologPdgfc79429Q9EQX6Rattus norvegicusPredictionMore>>
1:1 orthologpdgfc560564E7FB33Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016020 membrane
GO:0008083 growth factor activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0048568 embryonic organ development
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0008284 positive regulation of cell population proliferation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0339 Growth factor
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR000859 CUB_dom
IPR029034 Cystine-knot_cytokine
IPR029817 PDGF-C
IPR000072 PDGF/VEGF_dom
IPR035914 Sperma_CUB_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS01180 CUB
PS50278 PDGF_2

Pfam

Pfam ID Pfam Term
PF00431 CUB
PF00341 PDGF