| Tag | Content |
|---|---|
| Uniprot ID | A0A452ET29 |
| Entrez ID | 102168934 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005691309.3 |
| Ensembl protein ID | ENSCHIP00000015270 |
| Ensembl nucleotide ID | ENSCHIG00000015981 |
| Gene name | Uncharacterized protein |
| Gene symbol | PDGFC |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGVCGKCPAR LGGQSRRGAS RPARPSPGGA DPGPEPRSPS ARRPRARPLS PMLLFGLLLL 60 TSALAGQRPG TRAESNLSSK LQLGSNKEQN GVQDPQHERI ITVSTNGSIH SPRFPHTYPR 120 NMDLVWRLVA VEENVWIQLT FDERFGLEDP EDDICKYDFV EVEEPSDGTI LGRWCGSGSV 180 PGKQISKGNQ IRIRFVSDEY FPSEPGFCIH YNIVMPQLTE TVSPSSLPAS ALPLDLLNNA 240 VTAFSTLEDL IRYLEPDRWQ LDLEDLYRPT SLQLLGKNFM FGRKSRVVDL NLLKEEVRLY 300 SCTPRNFSVS VREELKRTDT IFWPGCLLVK RCGGNCACCL QTCSECQCVP SKVTKKYHEV 360 LQLRPKTGVR GLHKSLTDVA LEHHEECDCV CRGNPGG 397 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PDGFC | 102168934 | A0A452ET29 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PDGFC | 100062015 | A0A3Q2HV05 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | PDGFC | 56034 | Q9NRA1 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Pdgfc | 54635 | Q8CI19 | CPO | E12.5, E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PDGFC | H2QQC3 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A481CL63 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | PDGFC | 100350272 | G1TDA1 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pdgfc | 79429 | Q9EQX6 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pdgfc | 560564 | E7FB33 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0005829 | cytosol |
| GO:0005615 | extracellular space |
| GO:0005886 | plasma membrane |
| GO:0008083 | growth factor activity |
| GO:0005161 | platelet-derived growth factor receptor binding |
| GO:0042803 | protein homodimerization activity |
| GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity |
| GO:0009887 | animal organ morphogenesis |
| GO:0060348 | bone development |
| GO:0071230 | cellular response to amino acid stimulus |
| GO:0048565 | digestive tract development |
| GO:0048568 | embryonic organ development |
| GO:0048008 | platelet-derived growth factor receptor signaling pathway |
| GO:0120162 | positive regulation of cold-induced thermogenesis |
| GO:0048146 | positive regulation of fibroblast proliferation |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation |