| Tag | Content |
|---|---|
| Uniprot ID | G1TDA1 |
| Entrez ID | 100350272 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002716942.3 |
| Ensembl protein ID | ENSOCUP00000014811 |
| Ensembl nucleotide ID | ENSOCUG00000017242 |
| Gene name | Platelet derived growth factor C |
| Gene symbol | PDGFC |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLLFGLFLLT SALAGQRPGT QAESNLSSKF QFSSNKEQNG VQDPQHERVI TVSTNGSIHS 60 PRFPHAYPRN TVLVWRLVAV EENVWIQLTF DERFGLEDPE DDICKYDFVE VEEPSDGTVL 120 GRWCGSGSVP GKQISKGNQI RIRFVSDEYF PSEPGFCIHY NIVMPQFTEA VSPSVLPASA 180 LPLDLLNNAV TAFSTLEDLI RYLEPDRWQL DLEDLYRPTW QLLGKAFVFG RKSRVVDLNL 240 LKEEVRLYSC TPRNFSVSIR EELKRTDTIF WPGCLLVKRC GGNCACCLHN CNECQCVPSK 300 VTKKYHEVLQ LRPKIGVRGL HKSLTDVALE HHEACDCVCR GNAGG 345 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PDGFC | 102168934 | A0A452ET29 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PDGFC | 100062015 | A0A3Q2HV05 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | PDGFC | 56034 | Q9NRA1 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Pdgfc | 54635 | Q8CI19 | CPO | E12.5, E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PDGFC | H2QQC3 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A481CL63 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | PDGFC | 100350272 | G1TDA1 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Pdgfc | 79429 | Q9EQX6 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pdgfc | 560564 | E7FB33 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0005829 | cytosol |
| GO:0005615 | extracellular space |
| GO:0005886 | plasma membrane |
| GO:0008083 | growth factor activity |
| GO:0005161 | platelet-derived growth factor receptor binding |
| GO:0042803 | protein homodimerization activity |
| GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity |
| GO:0009887 | animal organ morphogenesis |
| GO:0060348 | bone development |
| GO:0071230 | cellular response to amino acid stimulus |
| GO:0048565 | digestive tract development |
| GO:0048568 | embryonic organ development |
| GO:0048008 | platelet-derived growth factor receptor signaling pathway |
| GO:0120162 | positive regulation of cold-induced thermogenesis |
| GO:0048146 | positive regulation of fibroblast proliferation |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation |