| Tag | Content |
|---|---|
| Uniprot ID | F1S0R5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000006462 |
| Ensembl nucleotide ID | ENSSSCG00000006052 |
| Gene name | Uncharacterized protein |
| Gene symbol | FZD6 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEMFTFLWTC IFLPLIRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QSIAAVEMEP 60 FLPLANLECS PNVETFLCKA FVPTCTEQID VVPPCRKFCE KVYSDCKKLM DTFGIRWPEE 120 LECNRLQYCD EPVPATFDPH TDFLSPQKKI EPVQRDIGFW CPRHLKTSGG QGYKFLGIDQ 180 CAPPCPNMYF KNDELEFAKS FIGIVSIFCL CATLFTFLTF LIDVRRFRYP ERPIIYYSVC 240 YSIVSLMYFI GFLLGNSTAC NKADEKLELG DTVVLGSQNK ACTVLFMFLY FFTMAGTVWW 300 VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGIPGFLTV MLLAMNKVEG DNISGVCFVG 360 LYDLDASRYF VLLPLCFCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF 420 SGLYLVPLVM LLGCYVYEQV NRITWEITWV SDHCRQYHIP CPYQAKTETR PELALFMMKY 480 MTLIVGISAV FWVGSKKTCT EWAGFFKRNR KKDPISESRR VLQESCEFFL KHNSKVKHKK 540 KHYKPSSHKL KVISKSMGTS TGATANHGTS AVAITNHDYL GQETLTEIQT SPETSVREVR 600 ADRASPPKAR EQDGEDPASS AASSSRLCGE QTDRKGRAGN VKDKSRVPAS ARSEGRVTPK 660 NDGTETSPAP SNSLQAPSSS EPGSLKGSTS LLVHSASGVR KEQGTGSHSD T 711 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FZD6 | 403610 | F1P9V1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | FZD6 | A0A452EZH8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FZD6 | 8323 | O60353 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Fzd6 | 14368 | Q61089 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | FZD6 | 464327 | H2R2C6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FZD6 | F1S0R5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FZD6 | 100344394 | G1SWP7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Fzd6 | 282581 | G3V6L1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0045177 | apical part of cell |
| GO:0016327 | apicolateral plasma membrane |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0031625 | ubiquitin protein ligase binding |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0033278 | cell proliferation in midbrain |
| GO:0035880 | embryonic nail plate morphogenesis |
| GO:0048105 | establishment of body hair planar orientation |
| GO:0001942 | hair follicle development |
| GO:0042472 | inner ear morphogenesis |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity |
| GO:0001843 | neural tube closure |
| GO:0030168 | platelet activation |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway |