Tag | Content |
---|---|
Uniprot ID | G1SWP7 |
Entrez ID | 100344394 |
Genbank protein ID | |
Genbank nucleotide ID | XM_002710725.3; XM_017341467.1; |
Ensembl protein ID | ENSOCUP00000007920 |
Ensembl nucleotide ID | ENSOCUG00000009180 |
Gene name | Frizzled class receptor 6 |
Gene symbol | FZD6 |
Organism | Oryctolagus cuniculus |
NCBI taxa ID | 9986 |
Cleft type | |
Developmental stage | |
Data sources | Homology search |
Reference | |
Functional description | |
Sequence | MDMFAFLLTC MFLPLIRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QGIAAVEMEH 60 FLPLANLECS PNVETFLCKA FIPTCTEQIH VIPPCRKFCE KVYSDCRKLI DTFGIRWPEE 120 LECNRLQYCD ETAPVTFDPH TEFLGPQKKT EQVQRDIGFW CPRHLKTSGG QGYKFLGIDQ 180 CAPPCPNMYF KSDELEFAKS FIGIVSIFCL CATLFTFLTF LIDVKRFRYP ERPIIYYSVC 240 YSIVSLIYFI GFLLGNNTAC NKADEKLELG DTVVLGSQNK ACTVLFMFLY FFTMAGTVWW 300 VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGIPGFLTV MLLAMNKVEG DNISGVCFVG 360 LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF 420 SGLYLVPLVT LLGCYVYEQV NRITWEITWV SDHCRQYHIP CPYQAKTKAR PELALFMIKY 480 LMTLIVGISP VFWVGSKKTC TEWAGFFKRN RKRDPISESR RVLQESCEFF LKHNSKVKHK 540 KKHYKPSSHK LKVISKSMGT STGATANHGT SAVAITDHDF LGQETLTEIQ TSPEASVREV 600 RADGASTPKV REQDCGEPAS PTAASAKVSG EQADKKSRAG SVKAKNSVSE GVRSEGRVSP 660 KSDDTDTGPV QSNNVQLASS SEPGSLKGST SLLVHSVPGV RKEQGAGSHS DT 712 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
---|---|---|---|---|---|---|---|---|
1:1 ortholog | FZD6 | 403610 | F1P9V1 | Canis lupus familiaris | Prediction | More>> | ||
1:1 ortholog | FZD6 | A0A452EZH8 | Capra hircus | Prediction | More>> | |||
1:1 ortholog | FZD6 | 8323 | O60353 | CL/P | Homo sapiens | Publication | More>> | |
1:1 ortholog | Fzd6 | 14368 | Q61089 | E14.5 | Mus musculus | Prediction | More>> | |
1:1 ortholog | FZD6 | 464327 | H2R2C6 | Pan troglodytes | Prediction | More>> | ||
1:1 ortholog | FZD6 | F1S0R5 | Sus scrofa | Prediction | More>> | |||
1:1 ortholog | FZD6 | 100344394 | G1SWP7 | Oryctolagus cuniculus | Prediction | More>> | ||
1:1 ortholog | Fzd6 | 282581 | G3V6L1 | Rattus norvegicus | Prediction | More>> |
GO ID | GO Term |
---|---|
GO:0045177 | apical part of cell |
GO:0016327 | apicolateral plasma membrane |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016021 | integral component of membrane |
GO:0031625 | ubiquitin protein ligase binding |
GO:0042813 | Wnt-activated receptor activity |
GO:0017147 | Wnt-protein binding |
GO:0033278 | cell proliferation in midbrain |
GO:0035880 | embryonic nail plate morphogenesis |
GO:0048105 | establishment of body hair planar orientation |
GO:0001942 | hair follicle development |
GO:0042472 | inner ear morphogenesis |
GO:0090090 | negative regulation of canonical Wnt signaling pathway |
GO:0043433 | negative regulation of DNA-binding transcription factor activity |
GO:0001843 | neural tube closure |
GO:0030168 | platelet activation |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway |