Logo
Home Search BLAST Integration Document Link Support Citation

Dataset Description
  • Dataset Name: 17973985
  • Species: Fly
  • Method: Microarray
  • No. of Genes: 109
  • Phenotype: Ethanol sensitivity
  • Publication: Morozova et al. Genome Biol. (2007) Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. PubMed
  • Dataset Summary: We performed artificial selection for alcohol sensitivity for 35 generations and created duplicate selection lines that are either highly sensitive or resistant to ethanol exposure along with unselected control lines. We used whole genome expression analysis to identify 1,678 probe sets with different expression levels between the divergent lines, pooled across replicates, at a false discovery rate of q < 0.001. We assessed to what extent genes with altered transcriptional regulation might be causally associated with ethanol sensitivity by measuring alcohol sensitivity of 37 co-isogenic P-element insertional mutations in 35 candidate genes, and found that 32 of these mutants differed in sensitivity to ethanol exposure from their co-isogenic controls. Furthermore, 23 of these novel genes have human orthologues.

    Gene list of this dataset (109 genes)
    Page: 1 2 3 list all   
    GeneIDSymbolNameGenetic locationOriginal ID1Original ID2
    41287CG14691-86C5-86C5CG14691 
    32597CalpC-14B13-14B13CalpC 
    31276CG14419-3C2-3C2CG14419 
    42416MtnC-92E4-92E4MtnC 
    39225Cpr67Fb-67F1-67F1CG18348 
    35538CG14590-42A9-42A9CG14590 
    34035Spn7-28B3-28B3Spn7 
    45285Dr-99B3-99B3Dr 
    326270MtnD-92F1-92F1MtnD 
    32420CG9509-13A1-13A1CG9509 
    35050CG18563-36C9-36C9CG18563 
    42313Dl-92A1-92A2Dl 
    33250CG13947-21E2-21E2CG13947 
    34640rho-6-33D2-33D2rho-6 
    50208CG16836-55C4-55C4CG16836 
    34517CG16743-32C1-32C1CG16743 
    35708CG2064-43E9-43E9CG2064 
    42598CG5778-94A2-94A2CG5778 
    40956CG7910-84E10-84E10CG7910 
    35735phr-43E18-43E18phr 
    38129LysP-61F4-61F4LySP 
    35735phr-43E18-43E18phr 
    38788CG32387-65E6-65E7CG32387 
    2768720Cyp12d1-d-47D4-47D4Cyp12d1-d 
    37102CG15067-55C4-55C4CG15067 
    246648Cyp12d1-p-47D4-47D4Cyp12d1-p 
    34467CG17107-32A4-32A4CG17107 
    36098Prx2540-2-47A7-47A7Prx2540-2 
    246399CG30026-47F10-47F10CG30026 
    38402CG14959-63C2-63C3CG14959 
    318238CG32834-59C1-59C1CG32834 
    33696CG2837-25B2-25B3CG2837 
    37130CG10924-55D1-55D2CG10924 
    37421CG15661-57D2-57D2CG15661 
    34052Acp1-28C2-28C2Acp1 
    3355141CG17478--CG17478 
    38633CG5150-64D5-64D5CG5150 
    41217CG34360-85E14-85E14CG33975 
    35216Lectin-galC1-37D6-37D6Lectin-galC1 
    36708Mtk-52A1-52A1Mtk 
    38858PGRP-SD-66A8-66A8PGRP-SD 
    32821Tsf1-17A9-17A9TSf1 
    37599CG4250-58F4-58F4CG4250 
    35774sut1-44A4-44A4Sut1 
    34453Trim9-31F5-32A2Trim9 
    35861PGRP-SC1b-44E2-44E2PGRP-SC1b 
    41330CG4757-86D5-86D5CG4757 
    40838dj-84B2-84B2dj 
    41213CG9459-85E10-85E10CG9459 
    34203CG9463-29F1-29F1CG9463 
    Page: 1 2 3 list all