Gene Page: GJC1

Summary
GeneID  10052
Symbol  GJC1
Synonyms  CX45|DKFZp686P0738|GJA7
Description  gap junction protein, gamma 1, 45kDa
See related  HGNC:4280|MIM:608655|Ensembl:ENSG00000182963|HPRD:08819|
Locus tag  -
Gene type  protein-coding
Map location  17q21.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATM0.890.90
CEP1920.870.85
CENPC10.850.85
EIF2C30.850.84
EYA30.850.85
C4orf210.850.82
FAM116A0.840.84
TRPM70.840.89
ANKHD10.840.81
ZNF4260.840.86
Top 10 negatively co-expressed genes
AF347015.31-0.62-0.70
IFI27-0.60-0.69
MT-CO2-0.60-0.68
HIGD1B-0.59-0.69
AF347015.21-0.59-0.71
AF347015.27-0.58-0.65
MT-CYB-0.57-0.64
CST3-0.57-0.67
AF347015.8-0.57-0.65
ENHO-0.55-0.72
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007268synaptic transmissionIEAneuron, Synap, Neurotransmitter (GO term level: 6)-
GO:0001570vasculogenesisIEA-
GO:0048468cell developmentIEA-
GO:0007601visual perceptionIEA-
GO:0006810transportNAS7966354 
GO:0007043cell-cell junction assemblyTAS7966354 
GO:0006936muscle contractionTAS7966354 
GO:0048738cardiac muscle developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016021integral to membraneIEA-
GO:0005922connexon complexIEA-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
TJP1DKFZp686M05161 | MGC133289 | ZO-1tight junction protein 1 (zona occludens 1)-HPRD11557048 |12064590|12064590 
-HPRD,BioGRID12064590 
TJP3MGC119546 | ZO-3tight junction protein 3 (zona occludens 3)-HPRD11557048 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_MEMBRANE_TRAFFICKING 12974All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_GAP_JUNCTION_TRAFFICKING 2719All SZGR genes in this pathway
REACTOME_GAP_JUNCTION_ASSEMBLY 1812All SZGR genes in this pathway
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP 205140All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP 14686All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP 181108All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 153102All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
BENPORATH_ES_2 4021All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G 9562All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_DN 277166All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_UP 166105All SZGR genes in this pathway
WINNEPENNINCKX_MELANOMA_METASTASIS_UP 16286All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
LU_EZH2_TARGETS_DN 414237All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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