Gene Page: CNTFR

Summary
GeneID  1271
Symbol  CNTFR
Synonyms  MGC1774
Description  ciliary neurotrophic factor receptor
See related  HGNC:2170|MIM:118946|Ensembl:ENSG00000122756|HPRD:00348|
Locus tag  -
Gene type  protein-coding
Map location  9p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TNFRSF190.740.65
DCT0.68-0.02
MSTN0.670.29
PDLIM10.670.40
NEUROD10.660.49
FGFR10.660.34
BOC0.650.42
JUB0.640.43
COL4A60.630.60
LTBP10.630.29
Top 10 negatively co-expressed genes
C5orf53-0.19-0.55
MGLL-0.18-0.30
ASPHD1-0.18-0.45
CCNI2-0.18-0.46
FBXO2-0.18-0.41
HLA-F-0.18-0.48
SLC16A11-0.18-0.41
INPP1-0.18-0.07
TMEM54-0.18-0.39
APOL1-0.17-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004897ciliary neurotrophic factor receptor activityTASneurotrophic (GO term level: 7)7585948 
GO:0004872receptor activityIEA-
GO:0004896cytokine receptor activityIEA-
GO:0005515protein bindingIEA-
GO:0019955cytokine bindingIPI15272019 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)7585948 
GO:0007165signal transductionNAS1648265 
GO:0008284positive regulation of cell proliferationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0005886plasma membraneIEA-
GO:0031225anchored to membraneIEA-
GO:0019898extrinsic to membraneTAS1648265 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APPBP2HS.84084 | KIAA0228 | PAT1amyloid beta precursor protein (cytoplasmic tail) binding protein 2Two-hybridBioGRID16189514 
CLCF1BSF3 | CISS2 | CLC | NNT1 | NR6cardiotrophin-like cytokine factor 1-HPRD,BioGRID11285233 
CNTFHCNTFciliary neurotrophic factor-HPRD,BioGRID7810882 |10812968 
CRLF1CISS | CISS1 | CLF | CLF-1 | NR6cytokine receptor-like factor 1-HPRD10966616 
IL6STCD130 | CDw130 | GP130 | GP130-RAPS | IL6R-betainterleukin 6 signal transducer (gp130, oncostatin M receptor)-HPRD11285233 
Affinity Capture-Western
Reconstituted Complex		BioGRID12707266 
KRTAP4-12KAP4.12 | KRTAP4.12keratin associated protein 4-12Two-hybridBioGRID16189514 
LIFRCD118 | FLJ98106 | FLJ99923 | LIF-R | SJS2 | STWS | SWSleukemia inhibitory factor receptor alpha-HPRD,BioGRID11285233 |11943154 
|12707266 
PLSCR1MMTRA1Bphospholipid scramblase 1Two-hybridBioGRID16189514 
 
Pathway annotation
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1466116171Ahsa-miR-146aUGAGAACUGAAUUCCAUGGGUU
hsa-miR-146bbrainUGAGAACUGAAUUCCAUAGGCU
miR-1982891A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-200bc/429510516m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-203.16296351Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-21392398m8hsa-miR-21brainUAGCUUAUCAGACUGAUGUUGA
hsa-miR-590GAGCUUAUUCAUAAAAGUGCAG
miR-222192251Ahsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-245662m8hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-28395401m8hsa-miR-28brainAAGGAGCUCACAGUCUAUUGAG
miR-37041471Ahsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
miR-3743893951Ahsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-485-5p348354m8hsa-miR-485-5pAGAGGCUGGCCGUGAUGAAUUC
miR-504365371m8hsa-miR-504AGACCCUGGUCUGCACUCUAU
miR-92342411A,m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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