Gene Page: CRABP1

Summary ?
GeneID1381
SymbolCRABP1
SynonymsCRABP|CRABP-I|CRABPI|RBP5
Descriptioncellular retinoic acid binding protein 1
ReferenceMIM:180230|HGNC:HGNC:2338|Ensembl:ENSG00000166426|HPRD:07520|Vega:OTTHUMG00000143862
Gene typeprotein-coding
Map location15q24
Pascal p-value0.085
Sherlock p-value0.004
Fetal beta-0.266
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17131472chr191962966CRABP113810.12trans
rs17535450chr239900012CRABP113810.03trans
rs11706314chr345309716CRABP113810trans
rs11706394chr345309907CRABP113810.01trans
rs2922180chr3125280472CRABP113810trans
rs2976809chr3125451738CRABP113815.004E-4trans
rs17090446chr462255221CRABP113810.15trans
rs4241605chr478161505CRABP113810.19trans
rs7668550chr4104384355CRABP113810.02trans
rs3796892chr4111404774CRABP113810.09trans
rs16894149chr561013724CRABP113810.02trans
rs6449550chr561034312CRABP113810.01trans
rs4489051chr5147954484CRABP113810.02trans
rs6874540chr5149911669CRABP113810.15trans
rs2273232chr5149912526CRABP113810.15trans
rs17056435chr5158453782CRABP113810.02trans
rs9313797chr5158465457CRABP113810.01trans
rs17056474chr5158468105CRABP113810.01trans
rs2294262chr616108966CRABP113810.11trans
rs6455226chr667930295CRABP113810.19trans
rs16868852chr670980333CRABP113810.2trans
rs9387571chr6118600137CRABP113810.08trans
rs283063chr6118621313CRABP113810.04trans
rs9321275chr6131493217CRABP113810.08trans
rs2430483chr7104548631CRABP113810.04trans
rs2199402chr89201002CRABP113810.01trans
rs7841407chr89243427CRABP113813.327E-4trans
rs2410231chr814954549CRABP113810.18trans
rs7029518chr937782560CRABP113810.11trans
rs10521469chr978884328CRABP113810.13trans
rs998410chr9117622673CRABP113810.07trans
rs9423711chr102574802CRABP113810.01trans
rs748375chr1033440178CRABP113810.14trans
rs11820030chr1176133564CRABP113810trans
rs17134872chr1176139845CRABP113811.674E-4trans
rs107512550CRABP113810.01trans
rs11236774chr1176234952CRABP113811.674E-4trans
rs11067174chr12115011927CRABP113810.08trans
rs4349050chr1341958722CRABP113810.19trans
rs7982172chr1341969697CRABP113810.16trans
rs4942043chr1341978218CRABP113810.13trans
rs1750009chr1342657093CRABP113810.02trans
rs9596788chr1353924430CRABP113810.04trans
rs9529974chr1372821935CRABP113813.842E-4trans
rs17720221chr1375182377CRABP113810.03trans
rs17073665chr1381541961CRABP113810.07trans
rs11840833chr1394378306CRABP113810.14trans
rs10149864chr1486719683CRABP113810.1trans
rs2093759chr1497171024CRABP113810.01trans
rs17244419chr1497171074CRABP113810trans
rs7165622chr1593979910CRABP113810.11trans
rs17294918chr1652717122CRABP113810.15trans
rs11873703chr1861448702CRABP113812.158E-5trans
rs17191809chr2136444778CRABP113810.03trans
rs6000401chr2237149335CRABP113810.16trans
rs5991662chrX43335796CRABP113810.19trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
FAM162A0.820.83
ACYP20.810.80
TM2D10.780.75
NDUFB50.770.74
MOCS20.760.73
ACOT130.750.80
TMEM126B0.750.75
CISD10.750.73
NDUFA40.750.77
NDUFA90.750.72
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
VAV2-0.57-0.56
KIAA1211-0.57-0.55
VASH1-0.57-0.57
C21orf30-0.57-0.60
NHSL1-0.57-0.64
KIAA1949-0.57-0.56
SH3BP2-0.57-0.66
GMIP-0.57-0.47
ANO8-0.56-0.59
LSS-0.56-0.59

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
LIU PROSTATE CANCER DN 481290All SZGR 2.0 genes in this pathway
LEE NEURAL CREST STEM CELL UP 14699All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION DN 329219All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN 232154All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 UP 5839All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS UP 12672All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION CDC25 UP 12073All SZGR 2.0 genes in this pathway
MARKEY RB1 CHRONIC LOF UP 11578All SZGR 2.0 genes in this pathway
MARKEY RB1 ACUTE LOF DN 228137All SZGR 2.0 genes in this pathway
TANAKA METHYLATED IN ESOPHAGEAL CARCINOMA 10358All SZGR 2.0 genes in this pathway
LA MEN1 TARGETS 2415All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR DN 428306All SZGR 2.0 genes in this pathway
RICKMAN HEAD AND NECK CANCER A 10063All SZGR 2.0 genes in this pathway
BENPORATH ES 1 379235All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BECKER TAMOXIFEN RESISTANCE UP 5036All SZGR 2.0 genes in this pathway
BHATTACHARYA EMBRYONIC STEM CELL 8960All SZGR 2.0 genes in this pathway
AFFAR YY1 TARGETS DN 234137All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY NO BLOOD DN 15093All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY DN 14588All SZGR 2.0 genes in this pathway
YAMAZAKI TCEB3 TARGETS DN 215132All SZGR 2.0 genes in this pathway
JACKSON DNMT1 TARGETS DN 2521All SZGR 2.0 genes in this pathway
BANDRES RESPONSE TO CARMUSTIN MGMT 48HR DN 161105All SZGR 2.0 genes in this pathway
CHEN ETV5 TARGETS TESTIS 2314All SZGR 2.0 genes in this pathway
DOUGLAS BMI1 TARGETS UP 566371All SZGR 2.0 genes in this pathway
KONDO PROSTATE CANCER HCP WITH H3K27ME3 9772All SZGR 2.0 genes in this pathway
MASSARWEH TAMOXIFEN RESISTANCE DN 258160All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B DN 564326All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL UP 648398All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME2 AND H3K27ME3 349234All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME2 AND H3K27ME3 5935All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S3 266180All SZGR 2.0 genes in this pathway
NAKAYAMA SOFT TISSUE TUMORS PCA1 DN 7447All SZGR 2.0 genes in this pathway
NAKAYAMA SOFT TISSUE TUMORS PCA2 UP 8750All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 16 7947All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857456All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE 1137655All SZGR 2.0 genes in this pathway
VANDESLUIS COMMD1 TARGETS GROUP 3 DN 3921All SZGR 2.0 genes in this pathway
FOSTER KDM1A TARGETS UP 266142All SZGR 2.0 genes in this pathway
BOSCO TH1 CYTOTOXIC MODULE 11462All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL DN 308187All SZGR 2.0 genes in this pathway
DURAND STROMA S UP 297194All SZGR 2.0 genes in this pathway