Gene Page: CYP2B6

Summary ?
GeneID1555
SymbolCYP2B6
SynonymsCPB6|CYP2B|CYP2B7|CYP2B7P|CYPIIB6|EFVM|IIB1|P450
Descriptioncytochrome P450 family 2 subfamily B member 6
ReferenceMIM:123930|HGNC:HGNC:2615|Ensembl:ENSG00000197408|HPRD:00477|Vega:OTTHUMG00000182714
Gene typeprotein-coding
Map location19q13.2
Pascal p-value0.964
Fetal beta0.011

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG ARACHIDONIC ACID METABOLISM 5836All SZGR 2.0 genes in this pathway
KEGG RETINOL METABOLISM 6437All SZGR 2.0 genes in this pathway
KEGG METABOLISM OF XENOBIOTICS BY CYTOCHROME P450 7044All SZGR 2.0 genes in this pathway
KEGG DRUG METABOLISM CYTOCHROME P450 7247All SZGR 2.0 genes in this pathway
REACTOME BIOLOGICAL OXIDATIONS 13991All SZGR 2.0 genes in this pathway
REACTOME XENOBIOTICS 1611All SZGR 2.0 genes in this pathway
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 5134All SZGR 2.0 genes in this pathway
REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS 7050All SZGR 2.0 genes in this pathway
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL UP 285181All SZGR 2.0 genes in this pathway
WATANABE COLON CANCER MSI VS MSS DN 8142All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS D UP 3823All SZGR 2.0 genes in this pathway
SAENZ DETOX PATHWAY AND CARCINOGENESIS DN 1311All SZGR 2.0 genes in this pathway
YANG BREAST CANCER ESR1 UP 3622All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882572All SZGR 2.0 genes in this pathway
WENG POR TARGETS GLOBAL UP 2014All SZGR 2.0 genes in this pathway
WENG POR DOSAGE 219All SZGR 2.0 genes in this pathway
WENG POR TARGETS LIVER UP 4129All SZGR 2.0 genes in this pathway
MCDOWELL ACUTE LUNG INJURY DN 4833All SZGR 2.0 genes in this pathway
YANG MUC2 TARGETS DUODENUM 3MO DN 2314All SZGR 2.0 genes in this pathway
YANG MUC2 TARGETS DUODENUM 6MO DN 2112All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE 35D DN 4934All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305895All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS DN 435289All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER GOOD SURVIVAL A4 196124All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN 17997All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SURVIVAL DN 11376All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA DN 267160All SZGR 2.0 genes in this pathway
GREGORY SYNTHETIC LETHAL WITH IMATINIB 14583All SZGR 2.0 genes in this pathway
SERVITJA LIVER HNF1A TARGETS UP 13596All SZGR 2.0 genes in this pathway