Summary ?
GeneID1663
SymbolDDX11
SynonymsCHL1|CHLR1|KRG2|WABS
DescriptionDEAD/H-box helicase 11
ReferenceMIM:601150|HGNC:HGNC:2736|Ensembl:ENSG00000013573|HPRD:03095|Vega:OTTHUMG00000168435
Gene typeprotein-coding
Map location12p11
Pascal p-value0.162
Sherlock p-value0.82
Fetal beta-0.482
DMG2 (# studies)
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Jaffe_2016Genome-wide DNA methylation analysisThis dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 2
DMG:vanEijk_2014Genome-wide DNA methylation analysisThis dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). 2
ExpressionMeta-analysis of gene expressionP value: 1.975 

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg251874631231226441DDX112.96E-8-0.0199.1E-6DMG:Jaffe_2016
cg093778991231226606DDX110.0025.378DMG:vanEijk_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs7297135chr1231225709DDX1116630.04cis
rs7971718chr1231310982DDX1116630.17cis
rs684454chr1231402689DDX1116630.04cis
rs11051381chr1231452749DDX1116630.11cis
rs1368303chr5147672388DDX1116630.07trans
rs4897051chr6149118925DDX1116630trans
rs17263352chr9124811572DDX1116630.19trans
rs7912228chr1012658396DDX1116630.13trans
rs6489532chr12570916DDX1116630.1trans
rs17104720chr1477127308DDX1116630trans
rs16955618chr1529937543DDX1116630.01trans
rs107717911231171563DDX11ENSG00000013573.122.263E-60-55216gtex_brain_ba24
rs107717921231171566DDX11ENSG00000013573.126.38E-100-55213gtex_brain_ba24
rs124252391231174002DDX11ENSG00000013573.126.38E-100-52777gtex_brain_ba24
rs350361231175617DDX11ENSG00000013573.121.139E-60-51162gtex_brain_ba24
rs133777221231176335DDX11ENSG00000013573.123.652E-110-50444gtex_brain_ba24
rs108438741231176849DDX11ENSG00000013573.123.468E-110-49930gtex_brain_ba24
rs107717931231177803DDX11ENSG00000013573.123.279E-110-48976gtex_brain_ba24
rs9182561231180354DDX11ENSG00000013573.122.503E-110-46425gtex_brain_ba24
rs107717941231183145DDX11ENSG00000013573.126.696E-120-43634gtex_brain_ba24
rs107717961231185709DDX11ENSG00000013573.122.447E-110-41070gtex_brain_ba24
rs169071601231187083DDX11ENSG00000013573.127.294E-100-39696gtex_brain_ba24
rs110512131231190931DDX11ENSG00000013573.124.857E-110-35848gtex_brain_ba24
rs563072351231191729DDX11ENSG00000013573.124.878E-110-35050gtex_brain_ba24
rs5314227721231196633DDX11ENSG00000013573.121.151E-100-30146gtex_brain_ba24
rs122967391231197575DDX11ENSG00000013573.123.746E-110-29204gtex_brain_ba24
rs40313731231201335DDX11ENSG00000013573.124.641E-110-25444gtex_brain_ba24
rs123032251231202563DDX11ENSG00000013573.123.264E-110-24216gtex_brain_ba24
rs350211231205358DDX11ENSG00000013573.121.361E-60-21421gtex_brain_ba24
rs25367031231213052DDX11ENSG00000013573.124.727E-100-13727gtex_brain_ba24
rs25367071231213483DDX11ENSG00000013573.121.025E-140-13296gtex_brain_ba24
rs45378461231213631DDX11ENSG00000013573.121.785E-170-13148gtex_brain_ba24
rs43622161231213644DDX11ENSG00000013573.121.062E-180-13135gtex_brain_ba24
rs43563151231213735DDX11ENSG00000013573.123.674E-260-13044gtex_brain_ba24
rs40313751231214179DDX11ENSG00000013573.121.374E-250-12600gtex_brain_ba24
rs110512271231215030DDX11ENSG00000013573.121.072E-250-11749gtex_brain_ba24
rs610080381231218038DDX11ENSG00000013573.121.335E-250-8741gtex_brain_ba24
rs110512311231221072DDX11ENSG00000013573.122.242E-260-5707gtex_brain_ba24
rs110512321231221455DDX11ENSG00000013573.121.594E-260-5324gtex_brain_ba24
rs124256831231222178DDX11ENSG00000013573.126.081E-230-4601gtex_brain_ba24
rs763493361231222479DDX11ENSG00000013573.127.303E-260-4300gtex_brain_ba24
rs25367331231222713DDX11ENSG00000013573.125.182E-150-4066gtex_brain_ba24
rs604411271231223086DDX11ENSG00000013573.121.793E-200-3693gtex_brain_ba24
rs108438771231223277DDX11ENSG00000013573.127.836E-140-3502gtex_brain_ba24
rs107717981231223322DDX11ENSG00000013573.126.769E-270-3457gtex_brain_ba24
rs25432461231223430DDX11ENSG00000013573.121.331E-220-3349gtex_brain_ba24
rs110512351231223471DDX11ENSG00000013573.121.298E-270-3308gtex_brain_ba24
rs38671491231224052DDX11ENSG00000013573.121.413E-270-2727gtex_brain_ba24
rs49314181231224452DDX11ENSG00000013573.121.559E-200-2327gtex_brain_ba24
rs49314201231224540DDX11ENSG00000013573.121.688E-280-2239gtex_brain_ba24
rs49314211231224665DDX11ENSG00000013573.122.395E-170-2114gtex_brain_ba24
rs49309501231224851DDX11ENSG00000013573.122.023E-260-1928gtex_brain_ba24
rs64879631231225099DDX11ENSG00000013573.126.432E-250-1680gtex_brain_ba24
rs64879641231225205DDX11ENSG00000013573.121.045E-240-1574gtex_brain_ba24
rs64879651231225213DDX11ENSG00000013573.121.167E-240-1566gtex_brain_ba24
rs64879661231225230DDX11ENSG00000013573.129.815E-250-1549gtex_brain_ba24
rs64879671231225344DDX11ENSG00000013573.123.569E-280-1435gtex_brain_ba24
rs64879681231225385DDX11ENSG00000013573.124.247E-280-1394gtex_brain_ba24
rs64879691231225411DDX11ENSG00000013573.121.535E-280-1368gtex_brain_ba24
rs64879701231225474DDX11ENSG00000013573.121.127E-280-1305gtex_brain_ba24
rs72975681231225778DDX11ENSG00000013573.121.586E-280-1001gtex_brain_ba24
rs73136391231225839DDX11ENSG00000013573.121.124E-270-940gtex_brain_ba24
rs284973451231226308DDX11ENSG00000013573.125.187E-210-471gtex_brain_ba24
rs38910061231226440DDX11ENSG00000013573.121.189E-290-339gtex_brain_ba24
rs79537061231226835DDX11ENSG00000013573.121.425E-28056gtex_brain_ba24
rs672417141231227175DDX11ENSG00000013573.123.675E-220396gtex_brain_ba24
rs73056631231227461DDX11ENSG00000013573.127.81E-290682gtex_brain_ba24
rs73058851231227480DDX11ENSG00000013573.129.213E-290701gtex_brain_ba24
rs71364001231227521DDX11ENSG00000013573.127.81E-290742gtex_brain_ba24
rs710524581231228235DDX11ENSG00000013573.122.248E-901456gtex_brain_ba24
rs595267771231228357DDX11ENSG00000013573.121.328E-2801578gtex_brain_ba24
rs49314231231228738DDX11ENSG00000013573.121.328E-2801959gtex_brain_ba24
rs49314241231229317DDX11ENSG00000013573.122.663E-2602538gtex_brain_ba24
rs49314251231229369DDX11ENSG00000013573.121.353E-2802590gtex_brain_ba24
rs113010651231229415DDX11ENSG00000013573.121.449E-2802636gtex_brain_ba24
rs49314261231229428DDX11ENSG00000013573.121.353E-2802649gtex_brain_ba24
rs49314271231229485DDX11ENSG00000013573.129.186E-2902706gtex_brain_ba24
rs22412871231230223DDX11ENSG00000013573.122.636E-2803444gtex_brain_ba24
rs110512361231230300DDX11ENSG00000013573.121.123E-2803521gtex_brain_ba24
rs714409321231230420DDX11ENSG00000013573.126.34E-2103641gtex_brain_ba24
rs71333631231230651DDX11ENSG00000013573.125.165E-2703872gtex_brain_ba24
rs348736121231230800DDX11ENSG00000013573.121.684E-2604021gtex_brain_ba24
rs1134632651231233023DDX11ENSG00000013573.121.083E-1806244gtex_brain_ba24
rs740879201231233053DDX11ENSG00000013573.127.378E-2106274gtex_brain_ba24
rs57973981231233537DDX11ENSG00000013573.125.385E-1206758gtex_brain_ba24
rs73095201231233957DDX11ENSG00000013573.129.177E-2907178gtex_brain_ba24
rs780713281231234920DDX11ENSG00000013573.123.338E-1208141gtex_brain_ba24
rs49309511231235354DDX11ENSG00000013573.121.59E-1508575gtex_brain_ba24
rs25531471231235395DDX11ENSG00000013573.121.916E-2108616gtex_brain_ba24
rs1122040421231236244DDX11ENSG00000013573.122.19E-2209465gtex_brain_ba24
rs21117661231236290DDX11ENSG00000013573.122.552E-1609511gtex_brain_ba24
rs21117671231236294DDX11ENSG00000013573.122.261E-1509515gtex_brain_ba24
rs108438791231237196DDX11ENSG00000013573.121.353E-28010417gtex_brain_ba24
rs39309061231237372DDX11ENSG00000013573.121.353E-28010593gtex_brain_ba24
rs38812961231237700DDX11ENSG00000013573.121.415E-28010921gtex_brain_ba24
rs49314281231238075DDX11ENSG00000013573.122.274E-22011296gtex_brain_ba24
rs40126191231239333DDX11ENSG00000013573.124.275E-18012554gtex_brain_ba24
rs23526221231239505DDX11ENSG00000013573.122.847E-26012726gtex_brain_ba24
rs611194391231239659DDX11ENSG00000013573.123.641E-16012880gtex_brain_ba24
rs107437501231240334DDX11ENSG00000013573.122.663E-26013555gtex_brain_ba24
rs73083681231240502DDX11ENSG00000013573.123.625E-19013723gtex_brain_ba24
rs73084941231240622DDX11ENSG00000013573.122.663E-26013843gtex_brain_ba24
rs73087541231240862DDX11ENSG00000013573.129.635E-24014083gtex_brain_ba24
rs73087731231240925DDX11ENSG00000013573.122.79E-26014146gtex_brain_ba24
rs73091891231240960DDX11ENSG00000013573.122.71E-26014181gtex_brain_ba24
rs108438801231241310DDX11ENSG00000013573.122.663E-26014531gtex_brain_ba24
rs108438811231241345DDX11ENSG00000013573.122.663E-26014566gtex_brain_ba24
rs597749261231241530DDX11ENSG00000013573.121.481E-26014751gtex_brain_ba24
rs110512391231241707DDX11ENSG00000013573.121.404E-26014928gtex_brain_ba24
rs20058961231242271DDX11ENSG00000013573.121.17E-18015492gtex_brain_ba24
rs20058971231242314DDX11ENSG00000013573.122.318E-18015535gtex_brain_ba24
rs38812981231242399DDX11ENSG00000013573.124.577E-15015620gtex_brain_ba24
rs20753181231242440DDX11ENSG00000013573.122.101E-20015661gtex_brain_ba24
rs20058981231242718DDX11ENSG00000013573.123.558E-26015939gtex_brain_ba24
rs413131571231242725DDX11ENSG00000013573.124.019E-26015946gtex_brain_ba24
rs20753191231243131DDX11ENSG00000013573.123.225E-10016352gtex_brain_ba24
rs1174797621231243172DDX11ENSG00000013573.122.051E-13016393gtex_brain_ba24
rs40313061231243841DDX11ENSG00000013573.122.24E-20017062gtex_brain_ba24
rs25432781231244238DDX11ENSG00000013573.121.519E-12017459gtex_brain_ba24
rs25531291231244281DDX11ENSG00000013573.121.276E-12017502gtex_brain_ba24
rs25432791231244299DDX11ENSG00000013573.123.925E-16017520gtex_brain_ba24
rs97881731231244592DDX11ENSG00000013573.122.474E-7017813gtex_brain_ba24
rs18083481231244846DDX11ENSG00000013573.128.911E-25018067gtex_brain_ba24
rs18083491231244924DDX11ENSG00000013573.121.288E-25018145gtex_brain_ba24
rs20753211231245741DDX11ENSG00000013573.123.588E-17018962gtex_brain_ba24
rs108438821231246371DDX11ENSG00000013573.121.818E-25019592gtex_brain_ba24
rs79700741231246438DDX11ENSG00000013573.122.624E-22019659gtex_brain_ba24
rs79553661231246448DDX11ENSG00000013573.128.938E-14019669gtex_brain_ba24
rs79554381231246751DDX11ENSG00000013573.122.129E-11019972gtex_brain_ba24
rs25531261231246840DDX11ENSG00000013573.129.647E-11020061gtex_brain_ba24
rs79556831231246884DDX11ENSG00000013573.121.379E-11020105gtex_brain_ba24
rs110512411231247098DDX11ENSG00000013573.124.899E-25020319gtex_brain_ba24
rs107718001231247986DDX11ENSG00000013573.123.576E-24021207gtex_brain_ba24
rs107718011231248336DDX11ENSG00000013573.124.921E-23021557gtex_brain_ba24
rs107718021231248430DDX11ENSG00000013573.126.74E-15021651gtex_brain_ba24
rs97881281231249118DDX11ENSG00000013573.127.245E-12022339gtex_brain_ba24
rs97880471231249225DDX11ENSG00000013573.128.204E-16022446gtex_brain_ba24
rs20753221231249861DDX11ENSG00000013573.121.714E-24023082gtex_brain_ba24
rs40312851231250400DDX11ENSG00000013573.123.511E-10023621gtex_brain_ba24
rs79715791231250669DDX11ENSG00000013573.121.711E-24023890gtex_brain_ba24
rs29093881231250768DDX11ENSG00000013573.127.409E-12023989gtex_brain_ba24
rs29093901231251070DDX11ENSG00000013573.124.06E-10024291gtex_brain_ba24
rs49314311231251544DDX11ENSG00000013573.121.694E-23024765gtex_brain_ba24
rs125817931231251803DDX11ENSG00000013573.121.979E-14025024gtex_brain_ba24
rs125792181231251810DDX11ENSG00000013573.121.101E-7025031gtex_brain_ba24
rs779019871231252018DDX11ENSG00000013573.124.172E-10025239gtex_brain_ba24
rs604291051231252348DDX11ENSG00000013573.121.081E-21025569gtex_brain_ba24
rs49314321231252886DDX11ENSG00000013573.123.848E-23026107gtex_brain_ba24
rs10464561231253995DDX11ENSG00000013573.127.723E-16027216gtex_brain_ba24
rs64879741231254221DDX11ENSG00000013573.123.159E-21027442gtex_brain_ba24
rs64879751231254256DDX11ENSG00000013573.123.285E-21027477gtex_brain_ba24
rs619186701231254522DDX11ENSG00000013573.121.804E-14027743gtex_brain_ba24
rs79528611231254642DDX11ENSG00000013573.121.126E-21027863gtex_brain_ba24
rs79663661231254701DDX11ENSG00000013573.123.094E-18027922gtex_brain_ba24
rs79662721231254752DDX11ENSG00000013573.129.936E-21027973gtex_brain_ba24
rs79665231231254959DDX11ENSG00000013573.122.466E-20028180gtex_brain_ba24
rs676952091231255055DDX11ENSG00000013573.124.74E-7028276gtex_brain_ba24
rs107718031231255263DDX11ENSG00000013573.126.443E-15028484gtex_brain_ba24
rs107718041231255626DDX11ENSG00000013573.125.391E-17028847gtex_brain_ba24
rs22874631231255654DDX11ENSG00000013573.121.202E-21028875gtex_brain_ba24
rs587403561231255772DDX11ENSG00000013573.123.432E-14028993gtex_brain_ba24
rs38253181231256075DDX11ENSG00000013573.121.283E-21029296gtex_brain_ba24
rs38253211231256164DDX11ENSG00000013573.121.069E-16029385gtex_brain_ba24
rs38253241231256219DDX11ENSG00000013573.123.445E-15029440gtex_brain_ba24
rs38253251231256220DDX11ENSG00000013573.123.349E-15029441gtex_brain_ba24
rs39256411231256342DDX11ENSG00000013573.121.282E-21029563gtex_brain_ba24
rs39256421231256368DDX11ENSG00000013573.123.983E-22029589gtex_brain_ba24
rs10464571231256546DDX11ENSG00000013573.122.043E-13029767gtex_brain_ba24
rs10464581231256905DDX11ENSG00000013573.125.893E-12030126gtex_brain_ba24
rs97501231257464DDX11ENSG00000013573.126.481E-19030685gtex_brain_ba24
rs112191231257695DDX11ENSG00000013573.129.918E-22030916gtex_brain_ba24
rs25432901231257998DDX11ENSG00000013573.121.685E-23031219gtex_brain_ba24
rs679506291231258573DDX11ENSG00000013573.127.524E-14031794gtex_brain_ba24
rs353074171231258697DDX11ENSG00000013573.121.516E-10031918gtex_brain_ba24
rs19747511231258718DDX11ENSG00000013573.125.718E-17031939gtex_brain_ba24
rs19747521231258728DDX11ENSG00000013573.125.695E-17031949gtex_brain_ba24
rs581928801231259027DDX11ENSG00000013573.122.837E-20032248gtex_brain_ba24
rs79575741231259372DDX11ENSG00000013573.129.885E-7032593gtex_brain_ba24
rs19747531231259576DDX11ENSG00000013573.124.633E-14032797gtex_brain_ba24
rs38624021231259594DDX11ENSG00000013573.122.184E-12032815gtex_brain_ba24
rs110512451231259935DDX11ENSG00000013573.123.315E-14033156gtex_brain_ba24
rs110512461231260085DDX11ENSG00000013573.122.853E-20033306gtex_brain_ba24
rs49309521231260135DDX11ENSG00000013573.122.663E-20033356gtex_brain_ba24
rs3978378891231260348DDX11ENSG00000013573.121.547E-15033569gtex_brain_ba24
rs2018803951231260353DDX11ENSG00000013573.124.544E-7033574gtex_brain_ba24
rs7311381231260682DDX11ENSG00000013573.122.077E-20033903gtex_brain_ba24
rs21117701231261371DDX11ENSG00000013573.121E-14034592gtex_brain_ba24
rs8820551231261402DDX11ENSG00000013573.126.02E-14034623gtex_brain_ba24
rs20059001231261698DDX11ENSG00000013573.122.323E-20034919gtex_brain_ba24
rs578462681231261813DDX11ENSG00000013573.121.995E-20035034gtex_brain_ba24
rs585116021231261869DDX11ENSG00000013573.121.203E-9035090gtex_brain_ba24
rs49314331231263752DDX11ENSG00000013573.123.026E-14036973gtex_brain_ba24
rs49309531231264743DDX11ENSG00000013573.122.268E-20037964gtex_brain_ba24
rs10535521231264770DDX11ENSG00000013573.122.315E-20037991gtex_brain_ba24
rs23028481231265823DDX11ENSG00000013573.121.245E-8039044gtex_brain_ba24
rs23028501231265925DDX11ENSG00000013573.123.723E-11039146gtex_brain_ba24
rs10535341231265983DDX11ENSG00000013573.123.384E-12039204gtex_brain_ba24
rs23028531231266042DDX11ENSG00000013573.127.149E-15039263gtex_brain_ba24
rs49314341231266287DDX11ENSG00000013573.123.927E-10039508gtex_brain_ba24
rs42448561231266313DDX11ENSG00000013573.121.132E-14039534gtex_brain_ba24
rs49309541231266659DDX11ENSG00000013573.123.884E-9039880gtex_brain_ba24
rs25433091231266682DDX11ENSG00000013573.121.523E-10039903gtex_brain_ba24
rs79686841231267744DDX11ENSG00000013573.122.043E-9040965gtex_brain_ba24
rs746338231231268062DDX11ENSG00000013573.123.186E-11041283gtex_brain_ba24
rs22874481231284740DDX11ENSG00000013573.121.357E-6057961gtex_brain_ba24
rs783522491231285804DDX11ENSG00000013573.121.402E-6059025gtex_brain_ba24
rs38536181231285991DDX11ENSG00000013573.121.456E-6059212gtex_brain_ba24
rs110512661231288955DDX11ENSG00000013573.121.327E-8062176gtex_brain_ba24
rs2001377771231293759DDX11ENSG00000013573.121.582E-8066980gtex_brain_ba24
rs49314481231294581DDX11ENSG00000013573.126.101E-8067802gtex_brain_ba24
rs99437741231297279DDX11ENSG00000013573.125.794E-8070500gtex_brain_ba24
rs5779630971231298716DDX11ENSG00000013573.121.881E-8071937gtex_brain_ba24
rs2000732681231299103DDX11ENSG00000013573.121.131E-7072324gtex_brain_ba24
rs99438011231299353DDX11ENSG00000013573.126.605E-8072574gtex_brain_ba24
rs603978751231300185DDX11ENSG00000013573.126.45E-8073406gtex_brain_ba24
rs40312371231300233DDX11ENSG00000013573.124.012E-7073454gtex_brain_ba24
rs110512741231301888DDX11ENSG00000013573.121.753E-7075109gtex_brain_ba24
rs107717911231171563DDX11ENSG00000013573.129.329E-70-55216gtex_brain_putamen_basal
rs107717921231171566DDX11ENSG00000013573.121.485E-100-55213gtex_brain_putamen_basal
rs124252391231174002DDX11ENSG00000013573.121.485E-100-52777gtex_brain_putamen_basal
rs350361231175617DDX11ENSG00000013573.122.504E-60-51162gtex_brain_putamen_basal
rs133777221231176335DDX11ENSG00000013573.121.582E-110-50444gtex_brain_putamen_basal
rs108438741231176849DDX11ENSG00000013573.121.495E-110-49930gtex_brain_putamen_basal
rs107717931231177803DDX11ENSG00000013573.121.314E-110-48976gtex_brain_putamen_basal
rs9182561231180354DDX11ENSG00000013573.122.05E-110-46425gtex_brain_putamen_basal
rs107717941231183145DDX11ENSG00000013573.122.147E-100-43634gtex_brain_putamen_basal
rs107717961231185709DDX11ENSG00000013573.123.151E-110-41070gtex_brain_putamen_basal
rs169071601231187083DDX11ENSG00000013573.121.708E-90-39696gtex_brain_putamen_basal
rs110512131231190931DDX11ENSG00000013573.122.812E-110-35848gtex_brain_putamen_basal
rs563072351231191729DDX11ENSG00000013573.122.692E-110-35050gtex_brain_putamen_basal
rs5314227721231196633DDX11ENSG00000013573.123.004E-110-30146gtex_brain_putamen_basal
rs122967391231197575DDX11ENSG00000013573.127.219E-120-29204gtex_brain_putamen_basal
rs40313731231201335DDX11ENSG00000013573.123.21E-110-25444gtex_brain_putamen_basal
rs123032251231202563DDX11ENSG00000013573.125.959E-120-24216gtex_brain_putamen_basal
rs350211231205358DDX11ENSG00000013573.123.236E-70-21421gtex_brain_putamen_basal
rs25367031231213052DDX11ENSG00000013573.122.319E-110-13727gtex_brain_putamen_basal
rs25367071231213483DDX11ENSG00000013573.123.701E-140-13296gtex_brain_putamen_basal
rs45378461231213631DDX11ENSG00000013573.125.965E-230-13148gtex_brain_putamen_basal
rs43622161231213644DDX11ENSG00000013573.127.633E-220-13135gtex_brain_putamen_basal
rs43563151231213735DDX11ENSG00000013573.122.539E-280-13044gtex_brain_putamen_basal
rs40313751231214179DDX11ENSG00000013573.121.027E-220-12600gtex_brain_putamen_basal
rs110512271231215030DDX11ENSG00000013573.129.725E-250-11749gtex_brain_putamen_basal
rs610080381231218038DDX11ENSG00000013573.123.146E-250-8741gtex_brain_putamen_basal
rs110512311231221072DDX11ENSG00000013573.121.539E-280-5707gtex_brain_putamen_basal
rs110512321231221455DDX11ENSG00000013573.122.051E-260-5324gtex_brain_putamen_basal
rs124256831231222178DDX11ENSG00000013573.121.46E-210-4601gtex_brain_putamen_basal
rs763493361231222479DDX11ENSG00000013573.125.646E-240-4300gtex_brain_putamen_basal
rs25367331231222713DDX11ENSG00000013573.122.226E-140-4066gtex_brain_putamen_basal
rs604411271231223086DDX11ENSG00000013573.121.766E-190-3693gtex_brain_putamen_basal
rs108438771231223277DDX11ENSG00000013573.121.142E-130-3502gtex_brain_putamen_basal
rs107717981231223322DDX11ENSG00000013573.128.555E-240-3457gtex_brain_putamen_basal
rs25432461231223430DDX11ENSG00000013573.121.372E-250-3349gtex_brain_putamen_basal
rs110512351231223471DDX11ENSG00000013573.122.901E-240-3308gtex_brain_putamen_basal
rs38671491231224052DDX11ENSG00000013573.124.596E-240-2727gtex_brain_putamen_basal
rs49314181231224452DDX11ENSG00000013573.123.696E-230-2327gtex_brain_putamen_basal
rs49314201231224540DDX11ENSG00000013573.121.476E-260-2239gtex_brain_putamen_basal
rs49314211231224665DDX11ENSG00000013573.123.906E-210-2114gtex_brain_putamen_basal
rs49309501231224851DDX11ENSG00000013573.123.162E-290-1928gtex_brain_putamen_basal
rs64879631231225099DDX11ENSG00000013573.123.527E-280-1680gtex_brain_putamen_basal
rs64879641231225205DDX11ENSG00000013573.121.186E-270-1574gtex_brain_putamen_basal
rs64879651231225213DDX11ENSG00000013573.121.209E-270-1566gtex_brain_putamen_basal
rs64879661231225230DDX11ENSG00000013573.121.204E-270-1549gtex_brain_putamen_basal
rs64879671231225344DDX11ENSG00000013573.123.849E-260-1435gtex_brain_putamen_basal
rs64879681231225385DDX11ENSG00000013573.123.809E-260-1394gtex_brain_putamen_basal
rs64879691231225411DDX11ENSG00000013573.124.488E-240-1368gtex_brain_putamen_basal
rs64879701231225474DDX11ENSG00000013573.121.022E-280-1305gtex_brain_putamen_basal
rs72975681231225778DDX11ENSG00000013573.127.33E-260-1001gtex_brain_putamen_basal
rs73136391231225839DDX11ENSG00000013573.121.48E-250-940gtex_brain_putamen_basal
rs284973451231226308DDX11ENSG00000013573.122.928E-180-471gtex_brain_putamen_basal
rs38910061231226440DDX11ENSG00000013573.123.891E-290-339gtex_brain_putamen_basal
rs79537061231226835DDX11ENSG00000013573.122.368E-28056gtex_brain_putamen_basal
rs672417141231227175DDX11ENSG00000013573.123.371E-210396gtex_brain_putamen_basal
rs73056631231227461DDX11ENSG00000013573.121.417E-280682gtex_brain_putamen_basal
rs73058851231227480DDX11ENSG00000013573.121.417E-280701gtex_brain_putamen_basal
rs71364001231227521DDX11ENSG00000013573.121.417E-280742gtex_brain_putamen_basal
rs710524581231228235DDX11ENSG00000013573.121.546E-1001456gtex_brain_putamen_basal
rs595267771231228357DDX11ENSG00000013573.127.932E-2901578gtex_brain_putamen_basal
rs49314231231228738DDX11ENSG00000013573.128.209E-2901959gtex_brain_putamen_basal
rs49314241231229317DDX11ENSG00000013573.128.04E-2902538gtex_brain_putamen_basal
rs49314251231229369DDX11ENSG00000013573.128.04E-2902590gtex_brain_putamen_basal
rs113010651231229415DDX11ENSG00000013573.127.487E-2902636gtex_brain_putamen_basal
rs49314261231229428DDX11ENSG00000013573.128.04E-2902649gtex_brain_putamen_basal
rs49314271231229485DDX11ENSG00000013573.127.411E-2902706gtex_brain_putamen_basal
rs22412871231230223DDX11ENSG00000013573.126.451E-2903444gtex_brain_putamen_basal
rs110512361231230300DDX11ENSG00000013573.128.368E-2903521gtex_brain_putamen_basal
rs714409321231230420DDX11ENSG00000013573.121.808E-2003641gtex_brain_putamen_basal
rs71333631231230651DDX11ENSG00000013573.124.466E-2403872gtex_brain_putamen_basal
rs348736121231230800DDX11ENSG00000013573.121.726E-2804021gtex_brain_putamen_basal
rs1134632651231233023DDX11ENSG00000013573.121.615E-1906244gtex_brain_putamen_basal
rs740879201231233053DDX11ENSG00000013573.121.104E-2106274gtex_brain_putamen_basal
rs57973981231233537DDX11ENSG00000013573.124.951E-1106758gtex_brain_putamen_basal
rs73095201231233957DDX11ENSG00000013573.127.106E-2907178gtex_brain_putamen_basal
rs780713281231234920DDX11ENSG00000013573.123.878E-1408141gtex_brain_putamen_basal
rs49309511231235354DDX11ENSG00000013573.121.263E-1108575gtex_brain_putamen_basal
rs25531471231235395DDX11ENSG00000013573.121.326E-1808616gtex_brain_putamen_basal
rs1122040421231236244DDX11ENSG00000013573.124.743E-2409465gtex_brain_putamen_basal
rs21117661231236290DDX11ENSG00000013573.122.242E-2009511gtex_brain_putamen_basal
rs21117671231236294DDX11ENSG00000013573.126.279E-2209515gtex_brain_putamen_basal
rs108438791231237196DDX11ENSG00000013573.128.748E-29010417gtex_brain_putamen_basal
rs39309061231237372DDX11ENSG00000013573.129.185E-29010593gtex_brain_putamen_basal
rs38812961231237700DDX11ENSG00000013573.128.062E-29010921gtex_brain_putamen_basal
rs49314281231238075DDX11ENSG00000013573.128.26E-24011296gtex_brain_putamen_basal
rs40126191231239333DDX11ENSG00000013573.121.99E-14012554gtex_brain_putamen_basal
rs23526221231239505DDX11ENSG00000013573.127.302E-29012726gtex_brain_putamen_basal
rs611194391231239659DDX11ENSG00000013573.126.824E-23012880gtex_brain_putamen_basal
rs107437501231240334DDX11ENSG00000013573.128.04E-29013555gtex_brain_putamen_basal
rs73083681231240502DDX11ENSG00000013573.121.589E-23013723gtex_brain_putamen_basal
rs73084941231240622DDX11ENSG00000013573.128.04E-29013843gtex_brain_putamen_basal
rs73087541231240862DDX11ENSG00000013573.125.781E-25014083gtex_brain_putamen_basal
rs73087731231240925DDX11ENSG00000013573.127.889E-29014146gtex_brain_putamen_basal
rs73091891231240960DDX11ENSG00000013573.128.04E-29014181gtex_brain_putamen_basal
rs108438801231241310DDX11ENSG00000013573.128.04E-29014531gtex_brain_putamen_basal
rs108438811231241345DDX11ENSG00000013573.128.04E-29014566gtex_brain_putamen_basal
rs597749261231241530DDX11ENSG00000013573.121.892E-29014751gtex_brain_putamen_basal
rs110512391231241707DDX11ENSG00000013573.121.225E-29014928gtex_brain_putamen_basal
rs20058961231242271DDX11ENSG00000013573.125.862E-12015492gtex_brain_putamen_basal
rs20058971231242314DDX11ENSG00000013573.126.218E-19015535gtex_brain_putamen_basal
rs38812981231242399DDX11ENSG00000013573.122.102E-13015620gtex_brain_putamen_basal
rs20753181231242440DDX11ENSG00000013573.124.756E-20015661gtex_brain_putamen_basal
rs20058981231242718DDX11ENSG00000013573.121.43E-28015939gtex_brain_putamen_basal
rs413131571231242725DDX11ENSG00000013573.127.409E-29015946gtex_brain_putamen_basal
rs1174797621231243172DDX11ENSG00000013573.125.983E-11016393gtex_brain_putamen_basal
rs40313061231243841DDX11ENSG00000013573.121.683E-28017062gtex_brain_putamen_basal
rs25432781231244238DDX11ENSG00000013573.125.779E-16017459gtex_brain_putamen_basal
rs25531291231244281DDX11ENSG00000013573.127.127E-12017502gtex_brain_putamen_basal
rs25432791231244299DDX11ENSG00000013573.122.859E-16017520gtex_brain_putamen_basal
rs97881731231244592DDX11ENSG00000013573.121.01E-11017813gtex_brain_putamen_basal
rs18083481231244846DDX11ENSG00000013573.128.18E-29018067gtex_brain_putamen_basal
rs18083491231244924DDX11ENSG00000013573.129.422E-29018145gtex_brain_putamen_basal
rs20753211231245741DDX11ENSG00000013573.122.474E-17018962gtex_brain_putamen_basal
rs108438821231246371DDX11ENSG00000013573.129.418E-29019592gtex_brain_putamen_basal
rs79700741231246438DDX11ENSG00000013573.125.235E-24019659gtex_brain_putamen_basal
rs79553661231246448DDX11ENSG00000013573.123.839E-13019669gtex_brain_putamen_basal
rs79554381231246751DDX11ENSG00000013573.122.068E-17019972gtex_brain_putamen_basal
rs25531261231246840DDX11ENSG00000013573.126.665E-11020061gtex_brain_putamen_basal
rs79556831231246884DDX11ENSG00000013573.123.072E-12020105gtex_brain_putamen_basal
rs110512411231247098DDX11ENSG00000013573.129.002E-29020319gtex_brain_putamen_basal
rs107718001231247986DDX11ENSG00000013573.121.075E-28021207gtex_brain_putamen_basal
rs107718011231248336DDX11ENSG00000013573.126.586E-23021557gtex_brain_putamen_basal
rs107718021231248430DDX11ENSG00000013573.127.317E-16021651gtex_brain_putamen_basal
rs97881281231249118DDX11ENSG00000013573.121.422E-11022339gtex_brain_putamen_basal
rs97880471231249225DDX11ENSG00000013573.124.308E-16022446gtex_brain_putamen_basal
rs20753221231249861DDX11ENSG00000013573.121.07E-28023082gtex_brain_putamen_basal
rs79715791231250669DDX11ENSG00000013573.121.079E-28023890gtex_brain_putamen_basal
rs29093881231250768DDX11ENSG00000013573.121.8E-13023989gtex_brain_putamen_basal
rs29093901231251070DDX11ENSG00000013573.122.081E-11024291gtex_brain_putamen_basal
rs49314311231251544DDX11ENSG00000013573.129.037E-25024765gtex_brain_putamen_basal
rs125817931231251803DDX11ENSG00000013573.122.327E-15025024gtex_brain_putamen_basal
rs125792181231251810DDX11ENSG00000013573.124.573E-12025031gtex_brain_putamen_basal
rs779019871231252018DDX11ENSG00000013573.121.366E-9025239gtex_brain_putamen_basal
rs604291051231252348DDX11ENSG00000013573.122.729E-19025569gtex_brain_putamen_basal
rs49314321231252886DDX11ENSG00000013573.122.615E-22026107gtex_brain_putamen_basal
rs10464561231253995DDX11ENSG00000013573.126.631E-18027216gtex_brain_putamen_basal
rs64879741231254221DDX11ENSG00000013573.124.309E-26027442gtex_brain_putamen_basal
rs64879751231254256DDX11ENSG00000013573.122.289E-20027477gtex_brain_putamen_basal
rs619186701231254522DDX11ENSG00000013573.129.435E-19027743gtex_brain_putamen_basal
rs79528611231254642DDX11ENSG00000013573.121.014E-27027863gtex_brain_putamen_basal
rs79663661231254701DDX11ENSG00000013573.125.478E-19027922gtex_brain_putamen_basal
rs79662721231254752DDX11ENSG00000013573.122.608E-25027973gtex_brain_putamen_basal
rs79665231231254959DDX11ENSG00000013573.125.22E-22028180gtex_brain_putamen_basal
rs107718031231255263DDX11ENSG00000013573.122.737E-17028484gtex_brain_putamen_basal
rs107718041231255626DDX11ENSG00000013573.122.726E-21028847gtex_brain_putamen_basal
rs22874631231255654DDX11ENSG00000013573.122.704E-25028875gtex_brain_putamen_basal
rs587403561231255772DDX11ENSG00000013573.127.431E-19028993gtex_brain_putamen_basal
rs38253181231256075DDX11ENSG00000013573.122.655E-25029296gtex_brain_putamen_basal
rs38253211231256164DDX11ENSG00000013573.122.725E-16029385gtex_brain_putamen_basal
rs38253241231256219DDX11ENSG00000013573.127.749E-16029440gtex_brain_putamen_basal
rs38253251231256220DDX11ENSG00000013573.128.32E-16029441gtex_brain_putamen_basal
rs39256411231256342DDX11ENSG00000013573.122.683E-25029563gtex_brain_putamen_basal
rs39256421231256368DDX11ENSG00000013573.122.622E-25029589gtex_brain_putamen_basal
rs10464571231256546DDX11ENSG00000013573.122.262E-16029767gtex_brain_putamen_basal
rs10464581231256905DDX11ENSG00000013573.122.961E-15030126gtex_brain_putamen_basal
rs97501231257464DDX11ENSG00000013573.121.379E-22030685gtex_brain_putamen_basal
rs112191231257695DDX11ENSG00000013573.129.07E-23030916gtex_brain_putamen_basal
rs25432901231257998DDX11ENSG00000013573.127.7E-19031219gtex_brain_putamen_basal
rs679506291231258573DDX11ENSG00000013573.121.734E-15031794gtex_brain_putamen_basal
rs353074171231258697DDX11ENSG00000013573.121.322E-13031918gtex_brain_putamen_basal
rs19747511231258718DDX11ENSG00000013573.123.478E-18031939gtex_brain_putamen_basal
rs19747521231258728DDX11ENSG00000013573.123.435E-18031949gtex_brain_putamen_basal
rs581928801231259027DDX11ENSG00000013573.122.117E-22032248gtex_brain_putamen_basal
rs19747531231259576DDX11ENSG00000013573.121.596E-17032797gtex_brain_putamen_basal
rs38624021231259594DDX11ENSG00000013573.121.632E-12032815gtex_brain_putamen_basal
rs110512451231259935DDX11ENSG00000013573.128.824E-20033156gtex_brain_putamen_basal
rs110512461231260085DDX11ENSG00000013573.126.941E-24033306gtex_brain_putamen_basal
rs49309521231260135DDX11ENSG00000013573.121.842E-24033356gtex_brain_putamen_basal
rs3978378891231260348DDX11ENSG00000013573.129.907E-21033569gtex_brain_putamen_basal
rs2018803951231260353DDX11ENSG00000013573.125.979E-8033574gtex_brain_putamen_basal
rs7311381231260682DDX11ENSG00000013573.123.41E-24033903gtex_brain_putamen_basal
rs21117701231261371DDX11ENSG00000013573.122.272E-16034592gtex_brain_putamen_basal
rs8820551231261402DDX11ENSG00000013573.127.728E-16034623gtex_brain_putamen_basal
rs20059001231261698DDX11ENSG00000013573.124.209E-24034919gtex_brain_putamen_basal
rs578462681231261813DDX11ENSG00000013573.126.699E-24035034gtex_brain_putamen_basal
rs585116021231261869DDX11ENSG00000013573.121.973E-10035090gtex_brain_putamen_basal
rs49314331231263752DDX11ENSG00000013573.121.069E-19036973gtex_brain_putamen_basal
rs49309531231264743DDX11ENSG00000013573.124.318E-24037964gtex_brain_putamen_basal
rs10535521231264770DDX11ENSG00000013573.124.456E-24037991gtex_brain_putamen_basal
rs23028481231265823DDX11ENSG00000013573.127.735E-16039044gtex_brain_putamen_basal
rs23028501231265925DDX11ENSG00000013573.123.223E-17039146gtex_brain_putamen_basal
rs10535341231265983DDX11ENSG00000013573.126.101E-17039204gtex_brain_putamen_basal
rs23028531231266042DDX11ENSG00000013573.122.918E-19039263gtex_brain_putamen_basal
rs49314341231266287DDX11ENSG00000013573.121.263E-6039508gtex_brain_putamen_basal
rs42448561231266313DDX11ENSG00000013573.126.943E-19039534gtex_brain_putamen_basal
rs49309541231266659DDX11ENSG00000013573.123.765E-11039880gtex_brain_putamen_basal
rs25433091231266682DDX11ENSG00000013573.126.352E-15039903gtex_brain_putamen_basal
rs79686841231267744DDX11ENSG00000013573.128.331E-12040965gtex_brain_putamen_basal
rs746338231231268062DDX11ENSG00000013573.123.021E-14041283gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AP001362.10.710.71
EHBP1L10.710.70
MESP10.710.71
C7orf500.670.63
HBQ10.670.70
MAGIX0.670.64
PPM1M0.660.70
FAM98C0.660.65
LIN7B0.660.62
HSD11B1L0.660.64
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
LIMCH1-0.35-0.30
C6orf204-0.34-0.32
ITSN1-0.34-0.31
ZNF652-0.33-0.33
RAI14-0.33-0.28
NFIA-0.33-0.26
FAM59A-0.33-0.23
C8orf79-0.33-0.22
KIF5B-0.32-0.32
FEM1C-0.32-0.28

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003677DNA bindingIEA-
GO:0003723RNA bindingIEA-
GO:0004003ATP-dependent DNA helicase activityIEA-
GO:0005524ATP bindingIEA-
GO:0016787hydrolase activityIEA-
GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000070mitotic sister chromatid segregationTAS9013641 
GO:0000084S phase of mitotic cell cycleTAS9013641 
GO:0000086G2/M transition of mitotic cell cycleTAS9013641 
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processIEA-
GO:0007049cell cycleIEA-
GO:0008284positive regulation of cell proliferationTAS9013641 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005730nucleolusTAS9013641 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME DIABETES PATHWAYS 13391All SZGR 2.0 genes in this pathway
REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S 4634All SZGR 2.0 genes in this pathway
REACTOME UNFOLDED PROTEIN RESPONSE 8051All SZGR 2.0 genes in this pathway
KORKOLA YOLK SAC TUMOR UP 2014All SZGR 2.0 genes in this pathway
LIU SOX4 TARGETS DN 309191All SZGR 2.0 genes in this pathway
DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA UP 368234All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS DN 310188All SZGR 2.0 genes in this pathway
NOJIMA SFRP2 TARGETS DN 2518All SZGR 2.0 genes in this pathway
WANG CLIM2 TARGETS UP 269146All SZGR 2.0 genes in this pathway
GINESTIER BREAST CANCER ZNF217 AMPLIFIED DN 335193All SZGR 2.0 genes in this pathway
GINESTIER BREAST CANCER 20Q13 AMPLIFICATION DN 180101All SZGR 2.0 genes in this pathway
MAYBURD RESPONSE TO L663536 DN 5632All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375806All SZGR 2.0 genes in this pathway
PATIL LIVER CANCER 747453All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 16521023All SZGR 2.0 genes in this pathway
PUJANA BRCA2 PCC NETWORK 423265All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648385All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN 10364All SZGR 2.0 genes in this pathway
ASTON MAJOR DEPRESSIVE DISORDER DN 160110All SZGR 2.0 genes in this pathway
MANALO HYPOXIA DN 289166All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR 681420All SZGR 2.0 genes in this pathway
WANG CISPLATIN RESPONSE AND XPC UP 202115All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway
LIN MELANOMA COPY NUMBER UP 7353All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 3D DN 270181All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING 510309All SZGR 2.0 genes in this pathway
MUELLER PLURINET 299189All SZGR 2.0 genes in this pathway
FOURNIER ACINAR DEVELOPMENT LATE 2 277172All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S1 237159All SZGR 2.0 genes in this pathway
DANG BOUND BY MYC 1103714All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS CALB1 CORR DN 3720All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP 570339All SZGR 2.0 genes in this pathway