Gene Page: DNM1

Summary
GeneID  1759
Symbol  DNM1
Synonyms  DNM
Description  dynamin 1
See related  HGNC:2972|MIM:602377|Ensembl:ENSG00000106976|HPRD:03851|
Locus tag  -
Gene type  protein-coding
Map location  9q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.3528 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003774motor activityIEA-
GO:0003924GTPase activityIEA-
GO:0003924GTPase activityTAS10944110 
GO:0005515protein bindingISS-
GO:0005525GTP bindingIEA-
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006898receptor-mediated endocytosisTAS8101525 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIEA-
GO:0005874microtubuleIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AMPHAMPH1amphiphysinAffinity Capture-Western
Reconstituted Complex		BioGRID9148966 |9280305 
|9341169 |9348539 
|11877424 
-HPRD9148966 |9348539 
|9694653 |11877424|10899172 
AP2A2ADTAB | CLAPA2 | HIP9 | HYPJadaptor-related protein complex 2, alpha 2 subunit-HPRD10430869 
ASB13FLJ13134 | MGC19879ankyrin repeat and SOCS box-containing 13Two-hybridBioGRID16169070 
BIN1AMPH2 | AMPHL | DKFZp547F068 | MGC10367 | SH3P9bridging integrator 1-HPRD,BioGRID9195986 |9280305 
CABIN1CAIN | KIAA0330 | PPP3INcalcineurin binding protein 1-HPRD,BioGRID10931822 
CLIC3-chloride intracellular channel 3-HPRD11563969 
CLIC4CLIC4L | DKFZp566G223 | FLJ38640 | H1 | MTCLIC | huH1 | p64H1chloride intracellular channel 4-HPRD11563969 
CLINT1CLINT | ENTH | EPN4 | EPNR | EPSINR | FLJ46753 | KIAA0171clathrin interactor 1Reconstituted ComplexBioGRID12429846 
CTTNEMS1 | FLJ34459cortactin-HPRD12419186 
DNM1DNMdynamin 1-HPRD,BioGRID7634088 
DNMBPKIAA1010 | TUBAdynamin binding protein-HPRD,BioGRID14506234 
DYRK1ADYRK | DYRK1 | HP86 | MNB | MNBHdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1AReconstituted ComplexBioGRID11877424 
EPS15AF-1P | AF1P | MLLT5epidermal growth factor receptor pathway substrate 15-HPRD11483962 
FERTYK3fer (fps/fes related) tyrosine kinaseCo-fractionationBioGRID9722593 
FNBP1FBP17 | KIAA0554 | MGC126804formin binding protein 1-HPRD,BioGRID15252009 
GNB2L1Gnb2-rs1 | H12.3 | HLC-7 | PIG21 | RACK1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1-HPRD12359736 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Affinity Capture-Western
Far Western
Reconstituted Complex		BioGRID8119878 |9009162 
-HPRD8119878 |11877424 
GRIN1NMDA1 | NMDAR1 | NR1glutamate receptor, ionotropic, N-methyl D-aspartate 1-HPRD10862698 
GRIN2DEB11 | NMDAR2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2D-HPRD10862698 
ITSN1ITSN | MGC134948 | MGC134949 | SH3D1A | SH3P17intersectin 1 (SH3 domain protein)-HPRD10373452 
KIAA1377-KIAA1377Two-hybridBioGRID16169070 
MAP3K10MLK2 | MSTmitogen-activated protein kinase kinase kinase 10Reconstituted ComplexBioGRID9742220 
MED313110004H13Rik | CGI-125 | FLJ27436 | FLJ36714 | Soh1mediator complex subunit 31Two-hybridBioGRID16169070 
MOBKL32C4D | CGI-95 | MGC12264 | MOB1 | MOB3 | PREI3MOB1, Mps One Binder kinase activator-like 3 (yeast)-HPRD11872741 
NCK1MGC12668 | NCK | NCKalphaNCK adaptor protein 1-HPRD,BioGRID10206341 
NCK2GRB4 | NCKbetaNCK adaptor protein 2-HPRD11557983 
NME2MGC111212 | NDPK-B | NDPKB | NM23-H2 | NM23B | pufnon-metastatic cells 2, protein (NM23B) expressed in-HPRD11872741 
PACSIN1KIAA1379 | SDPIprotein kinase C and casein kinase substrate in neurons 1-HPRD,BioGRID11082044 
-HPRD9950691 |11082044 
PACSIN2SDPIIprotein kinase C and casein kinase substrate in neurons 2Reconstituted ComplexBioGRID11082044 
PACSIN3SDPIIIprotein kinase C and casein kinase substrate in neurons 3-HPRD,BioGRID11082044 
PFN2D3S1319E | PFLprofilin 2-HPRD9463375 
PIAS1DDXBP1 | GBP | GU/RH-II | MGC141878 | MGC141879 | ZMIZ3protein inhibitor of activated STAT, 1-HPRD15123615 
PIN4EPVH | MGC138486 | PAR14 | PAR17protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)Two-hybridBioGRID16169070 
PRNPASCR | CD230 | CJD | GSS | MGC26679 | PRIP | PrP | PrP27-30 | PrP33-35C | PrPc | prionprion protein-HPRD15146195 
SH3GL1CNSA1 | EEN | MGC111371 | SH3D2B | SH3P8SH3-domain GRB2-like 1-HPRD,BioGRID9238017 |10764144 
SH3GL2CNSA2 | EEN-B1 | FLJ20276 | FLJ25015 | SH3D2A | SH3P4SH3-domain GRB2-like 2Reconstituted ComplexBioGRID9341169 |12456676 
-HPRD11877424 
-HPRD9238017 |11877424 
SH3GL3CNSA3 | EEN-2B-L3 | EEN-B2 | HsT19371 | SH3D2C | SH3P13SH3-domain GRB2-like 3Endophilin A3 interacts with Dynamin.BIND11894096 
-HPRD9238017 
SH3GLB1Bif-1 | CGI-61 | KIAA0491 | dJ612B15.2SH3-domain GRB2-like endophilin B1Reconstituted ComplexBioGRID12456676 
SNAP25FLJ23079 | RIC-4 | RIC4 | SEC9 | SNAP | SNAP-25 | bA416N4.2 | dJ1068F16.2synaptosomal-associated protein, 25kDa-HPRD10373452 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 9771All SZGR genes in this pathway
BIOCARTA_NDKDYNAMIN_PATHWAY 2115All SZGR genes in this pathway
BIOCARTA_GABA_PATHWAY 1010All SZGR genes in this pathway
BIOCARTA_BARR_MAPK_PATHWAY 1211All SZGR genes in this pathway
BIOCARTA_BARRESTIN_SRC_PATHWAY 1514All SZGR genes in this pathway
BIOCARTA_BARRESTIN_PATHWAY 108All SZGR genes in this pathway
PID_NOTCH_PATHWAY 5949All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY 4038All SZGR genes in this pathway
PID_TXA2PATHWAY 5743All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_TRKR_PATHWAY 6248All SZGR genes in this pathway
PID_IL8_CXCR2_PATHWAY 3426All SZGR genes in this pathway
PID_ERBB1_INTERNALIZATION_PATHWAY 4135All SZGR genes in this pathway
PID_CXCR3_PATHWAY 4334All SZGR genes in this pathway
PID_THROMBIN_PAR1_PATHWAY 4332All SZGR genes in this pathway
PID_IL8_CXCR1_PATHWAY 2819All SZGR genes in this pathway
PID_EPHRINB_REV_PATHWAY 3025All SZGR genes in this pathway
REACTOME_GAP_JUNCTION_DEGRADATION 108All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_MEMBRANE_TRAFFICKING 12974All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 9161All SZGR genes in this pathway
REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING 137All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS 8662All SZGR genes in this pathway
REACTOME_RECYCLING_PATHWAY_OF_L1 2715All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_TOLL_RECEPTOR_CASCADES 11884All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
REACTOME_GAP_JUNCTION_TRAFFICKING 2719All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_UP 86All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN 234147All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN 8454All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_DN 10267All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
JIANG_AGING_HYPOTHALAMUS_DN 4031All SZGR genes in this pathway
DASU_IL6_SIGNALING_SCAR_UP 3021All SZGR genes in this pathway
BURTON_ADIPOGENESIS_7 5134All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_DN 5443All SZGR genes in this pathway
BURTON_ADIPOGENESIS_9 9259All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_DN 209137All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
VALK_AML_CLUSTER_11 3624All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_DN 5230All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
DASU_IL6_SIGNALING_UP 5944All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_GENES 9054All SZGR genes in this pathway
BILANGES_SERUM_RESPONSE_TRANSLATION 3720All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
PECE_MAMMARY_STEM_CELL_DN 14688All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-2241071141A,m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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