Gene Page: ELF2
Summary ?
| GeneID | 1998 |
| Symbol | ELF2 |
| Synonyms | EU32|NERF|NERF-1A|NERF-1B|NERF-1a,b|NERF-2 |
| Description | E74 like ETS transcription factor 2 |
| Reference | HGNC:HGNC:3317|Ensembl:ENSG00000109381|HPRD:16856|Vega:OTTHUMG00000133383 |
| Gene type | protein-coding |
| Map location | 4q28 |
| Pascal p-value | 0.002 |
| Sherlock p-value | 0.575 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AC027277.1 | 0.77 | 0.77 |
| LAMB2 | 0.64 | 0.65 |
| MICA | 0.63 | 0.70 |
| TCIRG1 | 0.63 | 0.65 |
| GSDMD | 0.63 | 0.70 |
| CTDSP1 | 0.62 | 0.69 |
| C11orf67 | 0.61 | 0.65 |
| NFKB2 | 0.60 | 0.65 |
| FES | 0.59 | 0.65 |
| FGR | 0.59 | 0.60 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GPR22 | -0.53 | -0.63 |
| TPM3 | -0.53 | -0.58 |
| ZNF622 | -0.52 | -0.57 |
| FAM49A | -0.51 | -0.54 |
| KHDRBS3 | -0.51 | -0.54 |
| NELL2 | -0.51 | -0.55 |
| C4orf16 | -0.51 | -0.56 |
| B3GALT2 | -0.51 | -0.53 |
| EIF4A2 | -0.51 | -0.53 |
| KHDRBS2 | -0.51 | -0.55 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PID ANGIOPOIETIN RECEPTOR PATHWAY | 50 | 41 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN | 805 | 505 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC DN | 537 | 339 | All SZGR 2.0 genes in this pathway |
| OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP UP | 69 | 40 | All SZGR 2.0 genes in this pathway |
| HADDAD B LYMPHOCYTE PROGENITOR | 293 | 193 | All SZGR 2.0 genes in this pathway |
| KAYO AGING MUSCLE UP | 244 | 165 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| DAZARD RESPONSE TO UV NHEK DN | 318 | 220 | All SZGR 2.0 genes in this pathway |
| BAELDE DIABETIC NEPHROPATHY DN | 434 | 302 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 6HR DN | 160 | 101 | All SZGR 2.0 genes in this pathway |
| RIZKI TUMOR INVASIVENESS 3D DN | 270 | 181 | All SZGR 2.0 genes in this pathway |
| WENDT COHESIN TARGETS UP | 33 | 19 | All SZGR 2.0 genes in this pathway |
| YAGI AML WITH T 9 11 TRANSLOCATION | 130 | 87 | All SZGR 2.0 genes in this pathway |
| FEVR CTNNB1 TARGETS DN | 553 | 343 | All SZGR 2.0 genes in this pathway |