Gene Page: LTN1
Summary ?
GeneID | 26046 |
Symbol | LTN1 |
Synonyms | C21orf10|C21orf98|RNF160|ZNF294 |
Description | listerin E3 ubiquitin protein ligase 1 |
Reference | MIM:613083|HGNC:HGNC:13082|Ensembl:ENSG00000198862|HPRD:10327|Vega:OTTHUMG00000078803 |
Gene type | protein-coding |
Map location | 21q22.11 |
Pascal p-value | 0.238 |
Sherlock p-value | 0.346 |
Fetal beta | 0.082 |
eGene | Anterior cingulate cortex BA24 Cerebellum |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs2832116 | 21 | 30228368 | LTN1 | ENSG00000198862.9 | 3.33725E-6 | 0.04 | 136902 | gtex_brain_ba24 |
rs2738953 | 21 | 30238363 | LTN1 | ENSG00000198862.9 | 3.03025E-6 | 0.04 | 126907 | gtex_brain_ba24 |
rs2705690 | 21 | 30239245 | LTN1 | ENSG00000198862.9 | 2.9625E-6 | 0.04 | 126025 | gtex_brain_ba24 |
rs2250139 | 21 | 30241955 | LTN1 | ENSG00000198862.9 | 2.9535E-6 | 0.04 | 123315 | gtex_brain_ba24 |
rs2250141 | 21 | 30241984 | LTN1 | ENSG00000198862.9 | 2.9535E-6 | 0.04 | 123286 | gtex_brain_ba24 |
rs1048546 | 21 | 30244877 | LTN1 | ENSG00000198862.9 | 2.9535E-6 | 0.04 | 120393 | gtex_brain_ba24 |
rs62222242 | 21 | 30249501 | LTN1 | ENSG00000198862.9 | 3.2334E-6 | 0.04 | 115769 | gtex_brain_ba24 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
LIU SOX4 TARGETS UP | 137 | 94 | All SZGR 2.0 genes in this pathway |
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP | 408 | 247 | All SZGR 2.0 genes in this pathway |
GARY CD5 TARGETS UP | 473 | 314 | All SZGR 2.0 genes in this pathway |
IVANOV MUTATED IN COLON CANCER | 13 | 9 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
STEGMEIER PRE-MITOTIC CELL CYCLE REGULATORS | 11 | 8 | All SZGR 2.0 genes in this pathway |
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP | 555 | 346 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 20HR UP | 240 | 152 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE DN | 1237 | 837 | All SZGR 2.0 genes in this pathway |
DURCHDEWALD SKIN CARCINOGENESIS DN | 264 | 168 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER UP | 973 | 570 | All SZGR 2.0 genes in this pathway |
MILI PSEUDOPODIA HAPTOTAXIS UP | 518 | 299 | All SZGR 2.0 genes in this pathway |
PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
BAKKER FOXO3 TARGETS DN | 187 | 109 | All SZGR 2.0 genes in this pathway |