Gene Page: DNAJC4
Summary ?
| GeneID | 3338 |
| Symbol | DNAJC4 |
| Synonyms | DANJC4|HSPF2|MCG18 |
| Description | DnaJ heat shock protein family (Hsp40) member C4 |
| Reference | MIM:604189|HGNC:HGNC:5271|Ensembl:ENSG00000110011|Vega:OTTHUMG00000167792 |
| Gene type | protein-coding |
| Map location | 11q13 |
| Pascal p-value | 0.012 |
| Sherlock p-value | 0.088 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| KCNAB1 | 0.76 | 0.77 |
| ANO3 | 0.75 | 0.69 |
| OTOF | 0.74 | 0.75 |
| SYTL5 | 0.74 | 0.73 |
| HTR1D | 0.73 | 0.66 |
| KL | 0.72 | 0.67 |
| ANKRD34B | 0.70 | 0.60 |
| RGS14 | 0.69 | 0.68 |
| HTR4 | 0.68 | 0.67 |
| TRAC | 0.68 | 0.44 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PLEKHO1 | -0.24 | -0.31 |
| NR2C2AP | -0.24 | -0.26 |
| SH2B2 | -0.24 | -0.44 |
| KIAA1949 | -0.24 | -0.31 |
| OLFM2 | -0.24 | -0.34 |
| TUBB2B | -0.23 | -0.38 |
| SH3BP2 | -0.23 | -0.44 |
| AC011491.1 | -0.23 | -0.25 |
| IGFBP2 | -0.23 | -0.35 |
| TRAF4 | -0.23 | -0.46 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PARENT MTOR SIGNALING DN | 46 | 29 | All SZGR 2.0 genes in this pathway |
| NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN | 634 | 384 | All SZGR 2.0 genes in this pathway |
| ONKEN UVEAL MELANOMA DN | 526 | 357 | All SZGR 2.0 genes in this pathway |
| ODONNELL TFRC TARGETS UP | 456 | 228 | All SZGR 2.0 genes in this pathway |
| FERREIRA EWINGS SARCOMA UNSTABLE VS STABLE DN | 98 | 59 | All SZGR 2.0 genes in this pathway |
| LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY UP | 109 | 69 | All SZGR 2.0 genes in this pathway |
| MOREAUX MULTIPLE MYELOMA BY TACI UP | 412 | 249 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| KIM GASTRIC CANCER CHEMOSENSITIVITY | 103 | 64 | All SZGR 2.0 genes in this pathway |
| WEST ADRENOCORTICAL TUMOR DN | 546 | 362 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN NPC ICP WITH H3K4ME3 | 445 | 257 | All SZGR 2.0 genes in this pathway |
| WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP | 397 | 206 | All SZGR 2.0 genes in this pathway |