Gene Page: IL9R
Summary ?
| GeneID | 3581 |
| Symbol | IL9R |
| Synonyms | CD129|IL-9R |
| Description | interleukin 9 receptor |
| Reference | MIM:300007|HGNC:HGNC:6030|Ensembl:ENSG00000124334|HPRD:02052|Vega:OTTHUMG00000022720 |
| Gene type | protein-coding |
| Map location | Xq28 and Yq12 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RGS10 | 0.69 | 0.66 |
| GPR34 | 0.64 | 0.55 |
| PTPLAD2 | 0.61 | 0.63 |
| MNDA | 0.61 | 0.61 |
| HLA-DMB | 0.60 | 0.63 |
| TYROBP | 0.60 | 0.60 |
| AIF1 | 0.60 | 0.58 |
| BLNK | 0.60 | 0.62 |
| PYCARD | 0.59 | 0.56 |
| TMEM126B | 0.59 | 0.60 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GLIS2 | -0.44 | -0.55 |
| AXIN1 | -0.44 | -0.51 |
| SAFB2 | -0.44 | -0.50 |
| SH3BP2 | -0.44 | -0.57 |
| ANO8 | -0.44 | -0.52 |
| SH2B2 | -0.44 | -0.58 |
| KIAA1949 | -0.44 | -0.51 |
| TNKS1BP1 | -0.43 | -0.50 |
| MORC2 | -0.43 | -0.50 |
| SEMA4C | -0.43 | -0.49 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION | 267 | 161 | All SZGR 2.0 genes in this pathway |
| KEGG JAK STAT SIGNALING PATHWAY | 155 | 105 | All SZGR 2.0 genes in this pathway |
| KEGG HEMATOPOIETIC CELL LINEAGE | 88 | 60 | All SZGR 2.0 genes in this pathway |
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | 663 | 425 | All SZGR 2.0 genes in this pathway |
| TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC DN | 187 | 115 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL LONG TERM | 302 | 191 | All SZGR 2.0 genes in this pathway |
| JIANG HYPOXIA NORMAL | 311 | 205 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
| VANASSE BCL2 TARGETS DN | 74 | 50 | All SZGR 2.0 genes in this pathway |
| YAGI AML WITH 11Q23 REARRANGED | 351 | 238 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 30MIN DN | 150 | 99 | All SZGR 2.0 genes in this pathway |