Gene Page: MAK

Summary
GeneID  4117
Symbol  MAK
Synonyms  dJ417M14.2
Description  male germ cell-associated kinase
See related  HGNC:6816|MIM:154235|Ensembl:ENSG00000111837|HPRD:01101|
Locus tag  RP3-417M14.2
Gene type  protein-coding
Map location  6p24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
STXBP5L0.810.74
DGKG0.780.69
ZBTB160.780.68
NPTX10.770.79
LUZP10.770.61
SLC4A100.760.68
ARHGAP260.760.67
CADPS20.760.78
CREG20.760.72
SLC45A40.760.64
Top 10 negatively co-expressed genes
BCL7C-0.38-0.56
FAM36A-0.34-0.32
HEBP2-0.34-0.54
RPL35-0.33-0.40
SH3BP2-0.33-0.45
FADS2-0.33-0.36
C9orf46-0.32-0.42
SH2B2-0.32-0.45
TRAF4-0.31-0.45
PKN1-0.31-0.36
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004693cyclin-dependent protein kinase activityIEAneuron (GO term level: 8)-
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingNAS-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationNAS-
GO:0007283spermatogenesisNAS2183027 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_AR_PATHWAY 6146All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR 3722All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS 9268All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
FIRESTEIN_PROLIFERATION 175125All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101139814051A,m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-144139914051Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-1822422491A,m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-543142614321Ahsa-miR-543AAACAUUCGCGGUGCACUUCU
hsa-miR-543AAACAUUCGCGGUGCACUUCU
miR-962432491Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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