Gene Page: STS

Summary
GeneID  412
Symbol  STS
Synonyms  ARSC|ARSC1|ASC|ES|SSDD
Description  steroid sulfatase (microsomal), isozyme S
See related  HGNC:11425|MIM:300747|Ensembl:ENSG00000101846|HPRD:02389|
Locus tag  -
Gene type  protein-coding
Map location  Xp22.32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 2.096 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PHGDH0.740.73
CTDSP10.730.74
TTYH10.730.73
C18orf510.710.71
LAMB20.710.72
LRP100.710.71
TRIP60.700.69
NLRX10.700.72
BMP70.700.69
DNASE20.700.66
Top 10 negatively co-expressed genes
KLHL1-0.49-0.41
FAM49A-0.47-0.44
ATXN7L1-0.47-0.42
DACT1-0.47-0.38
MYT1L-0.47-0.43
PRKAR2B-0.46-0.43
AGTPBP1-0.46-0.45
DAAM1-0.46-0.44
NOL4-0.46-0.42
TBC1D30-0.46-0.41
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0004773steryl-sulfatase activityTAS2668275 
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008544epidermis developmentTAS9252398 
GO:0008152metabolic processIEA-
GO:0007565female pregnancyIEA-
GO:0006706steroid catabolic processTAS6957717 
GO:0006629lipid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005792microsomeTAS6957717 
GO:0005794Golgi apparatusTAS2668275 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005624membrane fractionTAS2668275 
GO:0005764lysosomeTAS2668275 
GO:0005768endosomeTAS2668275 
GO:0005783endoplasmic reticulumTAS2668275 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneTAS2668275 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_STEROID_HORMONE_BIOSYNTHESIS 5530All SZGR genes in this pathway
REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION 2717All SZGR genes in this pathway
REACTOME_GLYCOSPHINGOLIPID_METABOLISM 3822All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM 198112All SZGR genes in this pathway
REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES 125All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_SPHINGOLIPID_METABOLISM 6940All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 188116All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
FRASOR_TAMOXIFEN_RESPONSE_DN 116All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_DN 241146All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_DN 10459All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP 194122All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_DN 240171All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_UP 14984All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_DN 2113All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT 10873All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_UP 183111All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_24HR_UP 1410All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_UP 222139All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
HUANG_FOXA2_TARGETS_DN 3621All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
VALK_AML_CLUSTER_5 3324All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP 19395All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_DN 11469All SZGR genes in this pathway


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