Summary ?
GeneID5119
SymbolCHMP1A
SynonymsCHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A
Descriptioncharged multivesicular body protein 1A
ReferenceMIM:164010|HGNC:HGNC:8740|Ensembl:ENSG00000131165|HPRD:01237|Vega:OTTHUMG00000169521
Gene typeprotein-coding
Map location16q24.3
Pascal p-value6.201E-5
Sherlock p-value0.913

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
TMC70.920.85
PLEKHH10.920.87
SHROOM40.910.86
AC022100.10.910.86
DOCK50.910.80
KIF13B0.910.80
GLDN0.900.82
ERBB30.900.83
C10orf900.900.79
PLD10.900.80
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
RPL35-0.55-0.75
RPL36-0.54-0.75
RPL27-0.53-0.74
SCNM1-0.53-0.63
RPL12-0.53-0.70
RPL8-0.52-0.69
RPL18-0.52-0.74
RPS18-0.52-0.71
RPSA-0.52-0.65
FAU-0.52-0.71

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
WAMUNYOKOLI OVARIAN CANCER LMP UP 265158All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL DN 186107All SZGR 2.0 genes in this pathway
GRUETZMANN PANCREATIC CANCER UP 358245All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP 479299All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957597All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 16Q24 AMPLICON 5338All SZGR 2.0 genes in this pathway
SMITH TERT TARGETS DN 8769All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE UP 244165All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 16911088All SZGR 2.0 genes in this pathway
SESTO RESPONSE TO UV C0 10772All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN 911527All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN 1011592All SZGR 2.0 genes in this pathway
GRATIAS RETINOBLASTOMA 16Q24 1715All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305895All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP 756494All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549316All SZGR 2.0 genes in this pathway
DELACROIX RARG BOUND MEF 367231All SZGR 2.0 genes in this pathway