Gene Page: CHMP1A
Summary ?
GeneID | 5119 |
Symbol | CHMP1A |
Synonyms | CHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A |
Description | charged multivesicular body protein 1A |
Reference | MIM:164010|HGNC:HGNC:8740|Ensembl:ENSG00000131165|HPRD:01237|Vega:OTTHUMG00000169521 |
Gene type | protein-coding |
Map location | 16q24.3 |
Pascal p-value | 6.201E-5 |
Sherlock p-value | 0.913 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
TMC7 | 0.92 | 0.85 |
PLEKHH1 | 0.92 | 0.87 |
SHROOM4 | 0.91 | 0.86 |
AC022100.1 | 0.91 | 0.86 |
DOCK5 | 0.91 | 0.80 |
KIF13B | 0.91 | 0.80 |
GLDN | 0.90 | 0.82 |
ERBB3 | 0.90 | 0.83 |
C10orf90 | 0.90 | 0.79 |
PLD1 | 0.90 | 0.80 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RPL35 | -0.55 | -0.75 |
RPL36 | -0.54 | -0.75 |
RPL27 | -0.53 | -0.74 |
SCNM1 | -0.53 | -0.63 |
RPL12 | -0.53 | -0.70 |
RPL8 | -0.52 | -0.69 |
RPL18 | -0.52 | -0.74 |
RPS18 | -0.52 | -0.71 |
RPSA | -0.52 | -0.65 |
FAU | -0.52 | -0.71 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
WAMUNYOKOLI OVARIAN CANCER LMP UP | 265 | 158 | All SZGR 2.0 genes in this pathway |
DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
HAMAI APOPTOSIS VIA TRAIL DN | 186 | 107 | All SZGR 2.0 genes in this pathway |
GRUETZMANN PANCREATIC CANCER UP | 358 | 245 | All SZGR 2.0 genes in this pathway |
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP | 479 | 299 | All SZGR 2.0 genes in this pathway |
LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
NIKOLSKY BREAST CANCER 16Q24 AMPLICON | 53 | 38 | All SZGR 2.0 genes in this pathway |
SMITH TERT TARGETS DN | 87 | 69 | All SZGR 2.0 genes in this pathway |
KAYO AGING MUSCLE UP | 244 | 165 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
SESTO RESPONSE TO UV C0 | 107 | 72 | All SZGR 2.0 genes in this pathway |
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN | 911 | 527 | All SZGR 2.0 genes in this pathway |
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN | 1011 | 592 | All SZGR 2.0 genes in this pathway |
GRATIAS RETINOBLASTOMA 16Q24 | 17 | 15 | All SZGR 2.0 genes in this pathway |
YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP | 756 | 494 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE VIA TP53 GROUP B | 549 | 316 | All SZGR 2.0 genes in this pathway |
DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |