Gene Page: PDZK1

Summary
GeneID  5174
Symbol  PDZK1
Synonyms  CAP70|CLAMP|NHERF3|PDZD1
Description  PDZ domain containing 1
See related  HGNC:8821|MIM:603831|Ensembl:ENSG00000174827|HPRD:04829|
Locus tag  -
Gene type  protein-coding
Map location  1q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005215transporter activityTAS9461128 
GO:0030165PDZ domain bindingIPI16236806 |16738539 
GO:0008022protein C-terminus bindingIPI15304510 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008283cell proliferationTAS9461128 
GO:0015893drug transportNAS16738539 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ABCC2ABC30 | CMOAT | DJS | KIAA1010 | MRP2 | cMRPATP-binding cassette, sub-family C (CFTR/MRP), member 2-HPRD,BioGRID10496535 |12615054 
AKAP10D-AKAP2 | MGC9414 | PRKA10A kinase (PRKA) anchor protein 10-HPRD,BioGRID14531806 
CFTRABC35 | ABCC7 | CF | CFTR/MRP | MRP7 | TNR-CFTR | dJ760C5.1cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)-HPRD,BioGRID11051556 |12471024 
|12615054 
CLCN3CLC3 | ClC-3chloride channel 3-HPRD,BioGRID12471024 
FARP2FIR | FRG | KIAA0793 | PLEKHC3FERM, RhoGEF and pleckstrin domain protein 2Reconstituted Complex
Two-hybrid		BioGRID14531806 
GFAPFLJ45472glial fibrillary acidic proteinTwo-hybridBioGRID16189514 
PDZK1IP1DD96 | MAP17 | RP1-18D14.5 | SPAPPDZK1 interacting protein 1-HPRD,BioGRID9461128 |12754212 
|12837682 |14531806 
PEX5FLJ50634 | FLJ50721 | FLJ51948 | PTS1-BP | PTS1R | PXR1peroxisomal biogenesis factor 5Two-hybridBioGRID16189514 
SCARB1CD36L1 | CLA-1 | CLA1 | MGC138242 | SR-BI | SRB1scavenger receptor class B, member 1-HPRD,BioGRID10829064 |12119305 
|14551195 
SLC17A1MGC126794 | MGC126796 | NAPI-1 | NPT-1 | NPT1solute carrier family 17 (sodium phosphate), member 1-HPRD,BioGRID14531806 
SLC22A12OAT4L | RST | URAT1solute carrier family 22 (organic anion/urate transporter), member 12-HPRD,BioGRID14531806 
SLC22A4MGC34546 | MGC40524 | OCTN1solute carrier family 22 (organic cation/ergothioneine transporter), member 4Reconstituted Complex
Two-hybrid		BioGRID14531806 
SLC34A3FLJ38680 | HHRH | NPTIIcsolute carrier family 34 (sodium phosphate), member 3Reconstituted Complex
Two-hybrid		BioGRID14531806 
SLC9A3MGC126718 | MGC126720 | NHE3solute carrier family 9 (sodium/hydrogen exchanger), member 3-HPRD,BioGRID14531806 
SLC9A3R1EBP50 | NHERF | NHERF1 | NPHLOP2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1Reconstituted Complex
Two-hybrid		BioGRID14531806 
SLC9A3R2E3KARP | MGC104639 | NHE3RF2 | NHERF-2 | NHERF2 | OCTS2 | SIP-1 | SIP1 | TKA-1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2Two-hybridBioGRID14531806 
SLKKIAA0204 | LOSK | MGC133067 | STK2 | bA16H23.1 | se20-9STE20-like kinase (yeast)Reconstituted Complex
Two-hybrid		BioGRID14531806 
UBE2IC358B7.1 | P18 | UBC9ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)Two-hybridBioGRID14531806 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_MTA3_PATHWAY 1910All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN 198110All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN 6943All SZGR genes in this pathway
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN 9153All SZGR genes in this pathway
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP 9459All SZGR genes in this pathway
SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN 6235All SZGR genes in this pathway
DOANE_BREAST_CANCER_ESR1_UP 11272All SZGR genes in this pathway
WANG_LMO4_TARGETS_UP 372227All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
ELVIDGE_HYPOXIA_DN 14694All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_DN 5940All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
KORKOLA_YOLK_SAC_TUMOR 6233All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
FRASOR_RESPONSE_TO_ESTRADIOL_UP 3728All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
BECKER_TAMOXIFEN_RESISTANCE_DN 5237All SZGR genes in this pathway
STOSSI_RESPONSE_TO_ESTRADIOL 5035All SZGR genes in this pathway
JIANG_HYPOXIA_CANCER 8352All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
MASSARWEH_RESPONSE_TO_ESTRADIOL 6147All SZGR genes in this pathway
MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP 2010All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
CADWELL_ATG16L1_TARGETS_UP 9356All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_UP 207143All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP 307182All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
OHGUCHI_LIVER_HNF4A_TARGETS_DN 14985All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C 9260All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP 8950All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway


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