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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PITX3

Summary

GeneID

5309

Symbol

PITX3

Synonyms

CTPP4|MGC12766|PTX3

Description

paired-like homeodomain 3

Locus tag

Gene type

protein-coding

Map location

10q25

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

CYBB

0.78

0.76

LCP1

0.75

0.70

DOCK2

0.75

0.71

ITGB2

0.74

0.70

NCKAP1L

0.74

0.68

TLR7

0.74

0.66

SYK

0.73

0.67

CSF1R

0.72

0.70

IRF8

0.72

0.67

LAPTM5

0.72

0.68

Top 10 negatively co-expressed genes

AF347015.18

-0.29

-0.28

AF347015.2

-0.28

-0.27

MT-CO2

-0.27

-0.28

AF347015.21

-0.27

-0.22

AF347015.31

-0.26

-0.27

AF347015.26

-0.25

-0.24

AF347015.8

-0.25

AC100783.1

-0.25

-0.27

IL32

-0.24

-0.20

CXCL14

-0.24

-0.19

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IEA

GO:0043565

sequence-specific DNA binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0048666

neuron development

IEA

neuron (GO term level: 9)

GO:0030901

midbrain development

IEA

Brain (GO term level: 8)

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0009887

organ morphogenesis

TAS

9620774

GO:0007275

multicellular organismal development

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS	652	441	All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP	268	157	All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING	510	309	All SZGR genes in this pathway
DAVIES_MULTIPLE_MYELOMA_VS_MGUS_UP	13	10	All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	1069	729	All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN	88	59	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D	280	158	All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF	516	308	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-133	220	226	m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	220	226	m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-328	236	242	1A	hsa-miR-328^brain	CUGGCCCUCUCUGCCCUUCCGU
miR-339	217	223	1A	hsa-miR-339	UCCCUGUCCUCCAGGAGCUCA
miR-542-5p	20	27	1A,m8	hsa-miR-542-5p	UCGGGGAUCAUCAUGUCACGAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.