Gene Page: ARL15
Summary ?
| GeneID | 54622 |
| Symbol | ARL15 |
| Synonyms | ARFRP2 |
| Description | ADP ribosylation factor like GTPase 15 |
| Reference | HGNC:HGNC:25945|Ensembl:ENSG00000185305|HPRD:12471|Vega:OTTHUMG00000162287 |
| Gene type | protein-coding |
| Map location | 5p15.2 |
| Pascal p-value | 0.13 |
| Fetal beta | -0.214 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs16894557 | chr6 | 28999825 | ARL15 | 54622 | 0.1 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| B4GALT3 | beta4Gal-T3 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | Two-hybrid | BioGRID | 16169070 |
| CCDC90B | MDS011 | MDS025 | MGC104239 | coiled-coil domain containing 90B | Two-hybrid | BioGRID | 16169070 |
| CRMP1 | DPYSL1 | DRP-1 | DRP1 | collapsin response mediator protein 1 | Two-hybrid | BioGRID | 16169070 |
| FUNDC2 | DC44 | FLJ33773 | HCBP6 | HCC3 | MGC131676 | MGC2495 | PD03104 | FUN14 domain containing 2 | Two-hybrid | BioGRID | 16169070 |
| GAPDH | G3PD | GAPD | MGC88685 | glyceraldehyde-3-phosphate dehydrogenase | Two-hybrid | BioGRID | 16169070 |
| GRIPAP1 | DKFZp434P0630 | GRASP-1 | KIAA1167 | MGC126593 | MGC126595 | GRIP1 associated protein 1 | Two-hybrid | BioGRID | 16169070 |
| PDE6D | PDED | phosphodiesterase 6D, cGMP-specific, rod, delta | Two-hybrid | BioGRID | 16169070 |
| PTN | HARP | HBGF8 | HBNF | NEGF1 | pleiotrophin | Two-hybrid | BioGRID | 16169070 |
| RPL8 | - | ribosomal protein L8 | Two-hybrid | BioGRID | 16169070 |
| TFG | FLJ36137 | TF6 | TRKT3 | TRK-fused gene | Two-hybrid | BioGRID | 16169070 |
| TUBB2A | TUBB | TUBB2 | dJ40E16.7 | tubulin, beta 2A | Two-hybrid | BioGRID | 16169070 |
| UBR1 | JBS | MGC142065 | MGC142067 | ubiquitin protein ligase E3 component n-recognin 1 | Two-hybrid | BioGRID | 16169070 |
| UNC119 | HRG4 | unc-119 homolog (C. elegans) | Two-hybrid | BioGRID | 16169070 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DUNNE TARGETS OF AML1 MTG8 FUSION UP | 52 | 32 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| NAKAYAMA FGF2 TARGETS | 29 | 17 | All SZGR 2.0 genes in this pathway |
| DUTERTRE ESTRADIOL RESPONSE 24HR DN | 505 | 328 | All SZGR 2.0 genes in this pathway |
| FIGUEROA AML METHYLATION CLUSTER 4 UP | 112 | 64 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF | 516 | 308 | All SZGR 2.0 genes in this pathway |