SZGR2

Summary ?

GeneID	60468
Symbol	BACH2
Synonyms	BTBD25
Description	BTB domain and CNC homolog 2
Reference	MIM:605394\|HGNC:HGNC:14078\|Ensembl:ENSG00000112182\|HPRD:12012\|Vega:OTTHUMG00000015216
Gene type	protein-coding
Map location	6q15
Pascal p-value	7.061E-4

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0003700	transcription factor activity	IEA		-
GO:0005515	protein binding	IEA		-
GO:0043565	sequence-specific DNA binding	IEA		-
GO:0046983	protein dimerization activity	IEA		-
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0006355	regulation of transcription, DNA-dependent	IEA		-
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005634	nucleus	IEA		-

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
HOLLMANN APOPTOSIS VIA CD40 DN	267	178	All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 DN	175	82	All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN	69	43	All SZGR 2.0 genes in this pathway
HUTTMANN B CLL POOR SURVIVAL DN	60	39	All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER DN	406	230	All SZGR 2.0 genes in this pathway
BILBAN B CLL LPL UP	63	39	All SZGR 2.0 genes in this pathway
HUMMEL BURKITTS LYMPHOMA UP	43	27	All SZGR 2.0 genes in this pathway
HAHTOLA SEZARY SYNDROM DN	42	26	All SZGR 2.0 genes in this pathway
MOTAMED RESPONSE TO ANDROGEN DN	6	5	All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP	1037	673	All SZGR 2.0 genes in this pathway
PASQUALUCCI LYMPHOMA BY GC STAGE DN	165	104	All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS	1062	725	All SZGR 2.0 genes in this pathway
MORI PLASMA CELL DN	33	20	All SZGR 2.0 genes in this pathway
HADDAD B LYMPHOCYTE PROGENITOR	293	193	All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP	1691	1088	All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER T7	98	63	All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P4	100	62	All SZGR 2.0 genes in this pathway
ZHENG FOXP3 TARGETS IN T LYMPHOCYTE DN	37	29	All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS UP	673	430	All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN	593	372	All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN	591	366	All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C D UP	139	95	All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS UNANNOTATED UP	85	50	All SZGR 2.0 genes in this pathway
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 UP	9	5	All SZGR 2.0 genes in this pathway
PASINI SUZ12 TARGETS DN	315	215	All SZGR 2.0 genes in this pathway
DURAND STROMA S UP	297	194	All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY	1725	838	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	553	559	m8	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-10	5364	5370	m8	hsa-miR-10a	UACCCUGUAGAUCCGAAUUUGUG
miR-10	5364	5370	m8	hsa-miR-10b	UACCCUGUAGAACCGAAUUUGU
miR-103/107	4725	4731	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
				hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
				hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
				hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-122	4655	4662	1A,m8	hsa-miR-122a	UGGAGUGUGACAAUGGUGUUUGU
miR-124.1	5333	5339	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	5333	5339	1A	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-129-5p	5775	5782	1A,m8	hsa-miR-129^brain	CUUUUUGCGGUCUGGGCUUGC
miR-129-5p	5775	5782	1A,m8	hsa-miR-129-5p	CUUUUUGCGGUCUGGGCUUGCU
miR-130/301	3709	3715	1A	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
				hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-137	131	137	1A	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-137	131	137	1A	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-142-3p	112	119	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-144	135	141	m8	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-145	516	523	1A,m8	hsa-miR-145	GUCCAGUUUUCCCAGGAAUCCCUU
miR-148/152	857	864	1A,m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-15/16/195/424/497	3695	3701	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-151	5823	5829	1A	hsa-miR-151^brain	ACUAGACUGAAGCUCCUUGAGG
miR-153	5381	5387	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-153	5381	5387	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-181	358	364	m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-182	1012	1019	1A,m8	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-183	1971	1977	m8	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-186	930	936	m8	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-190	5445	5451	m8	hsa-miR-190	UGAUAUGUUUGAUAUAUUAGGU
miR-29	193	200	1A,m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-30-5p	1783	1789	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-31	1010	1017	1A,m8	hsa-miR-31	AGGCAAGAUGCUGGCAUAGCUG
miR-324-5p	5123	5129	m8	hsa-miR-324-5p	CGCAUCCCCUAGGGCAUUGGUGU
miR-339	268	274	1A	hsa-miR-339	UCCCUGUCCUCCAGGAGCUCA
miR-363	5773	5779	1A	hsa-miR-363	AUUGCACGGUAUCCAUCUGUAA
miR-378	344	350	1A	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU
miR-384	998	1004	1A	hsa-miR-384	AUUCCUAGAAAUUGUUCAUA
miR-409-3p	552	558	m8	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU
miR-448	5381	5387	1A	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-448	5381	5387	1A	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-450	5775	5781	1A	hsa-miR-450	UUUUUGCGAUGUGUUCCUAAUA
miR-490	5499	5505	1A	hsa-miR-490	CAACCUGGAGGACUCCAUGCUG
miR-496	2000	2007	1A,m8	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-504	5365	5371	m8	hsa-miR-504	AGACCCUGGUCUGCACUCUAU
miR-539	313	319	1A	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU
miR-542-3p	328	334	1A	hsa-miR-542-3p	UGUGACAGAUUGAUAACUGAAA
miR-543	359	365	m8	hsa-miR-543	AAACAUUCGCGGUGCACUUCU
miR-96	1013	1019	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC
miR-96	1013	1019	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.

Gene Page: BACH2