Gene Page: CCL1

Summary ?
GeneID6346
SymbolCCL1
SynonymsI-309|P500|SCYA1|SISe|TCA3
DescriptionC-C motif chemokine ligand 1
ReferenceMIM:182281|HGNC:HGNC:10609|Ensembl:ENSG00000108702|HPRD:01654|Vega:OTTHUMG00000132888
Gene typeprotein-coding
Map location17q12
Pascal p-value0.837

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
VAT10.880.87
GPRIN20.880.86
DOK40.870.90
LIMK20.870.76
EFNA20.870.83
INA0.860.88
ST8SIA20.860.87
SLC37A10.860.89
AC110814.10.850.89
FBLIM10.850.83
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HLA-F-0.62-0.77
C5orf53-0.62-0.76
ALDOC-0.59-0.69
AF347015.27-0.58-0.86
AF347015.31-0.58-0.86
SPARCL1-0.58-0.66
FBXO2-0.58-0.62
CA4-0.58-0.68
HEPN1-0.57-0.73
TSC22D4-0.57-0.75

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION 267161All SZGR 2.0 genes in this pathway
KEGG CHEMOKINE SIGNALING PATHWAY 190128All SZGR 2.0 genes in this pathway
OKUMURA INFLAMMATORY RESPONSE LPS 183115All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED UP 183111All SZGR 2.0 genes in this pathway
LEE AGING NEOCORTEX DN 8049All SZGR 2.0 genes in this pathway
SAFFORD T LYMPHOCYTE ANERGY 8754All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022619All SZGR 2.0 genes in this pathway
WORSCHECH TUMOR REJECTION UP 5632All SZGR 2.0 genes in this pathway
GAURNIER PSMD4 TARGETS 7355All SZGR 2.0 genes in this pathway
LINDSTEDT DENDRITIC CELL MATURATION A 6752All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 2 2914All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 3 3312All SZGR 2.0 genes in this pathway
FONTAINE THYROID TUMOR UNCERTAIN MALIGNANCY UP 3623All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR DN 3619All SZGR 2.0 genes in this pathway
KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR DN 8859All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS CALB1 CORR DN 3720All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 1 DN 4830All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 6 DN 3819All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D 882506All SZGR 2.0 genes in this pathway
BOSCO ALLERGEN INDUCED TH2 ASSOCIATED MODULE 15186All SZGR 2.0 genes in this pathway
NABA SECRETED FACTORS 344197All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway