Gene Page: SGCD

Summary
GeneID  6444
Symbol  SGCD
Synonyms  35DAG|CMD1L|DAGD|MGC22567|SG-delta|SGCDP|SGD
Description  sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
See related  HGNC:10807|MIM:601411|Ensembl:ENSG00000170624|HPRD:03246|
Locus tag  -
Gene type  protein-coding
Map location  5q33-q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01718 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00459 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
B4GALT50.930.95
SLAIN20.930.94
CLASP10.920.94
ZNF8280.920.93
SEC31A0.920.94
EXOC20.920.95
POLR3A0.920.94
STAU10.920.93
WDR820.910.94
KBTBD60.910.94
Top 10 negatively co-expressed genes
FXYD1-0.73-0.86
AF347015.31-0.71-0.84
MT-CO2-0.71-0.86
AF347015.27-0.71-0.83
C5orf53-0.71-0.75
S100B-0.71-0.81
HSD17B14-0.71-0.78
AF347015.33-0.70-0.83
TSC22D4-0.70-0.77
AIFM3-0.69-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007010cytoskeleton organizationIEA-
GO:0007517muscle developmentTAS8841194 |8842738 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIEA-
GO:0005737cytoplasmIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneTAS8842738 
GO:0016012sarcoglycan complexIEA-
GO:0016012sarcoglycan complexTAS8841194 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FLNCABP-280 | ABP280A | ABPA | ABPL | FLJ10186 | FLN2filamin C, gamma (actin binding protein 280)-HPRD,BioGRID10629222 |14506720 
SGCBA3b | LGMD2E | SGCsarcoglycan, beta (43kDa dystrophin-associated glycoprotein)-HPRD9864373 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 8565All SZGR genes in this pathway
KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 7659All SZGR genes in this pathway
KEGG_DILATED_CARDIOMYOPATHY 9268All SZGR genes in this pathway
KEGG_VIRAL_MYOCARDITIS 7358All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
NEWMAN_ERCC6_TARGETS_DN 3924All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION 5026All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_DN 178121All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6 189112All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
CHANG_CYCLING_GENES 14883All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 13785All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2 182102All SZGR genes in this pathway
STAMBOLSKY_TARGETS_OF_MUTATED_TP53_UP 4935All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_DN 418245All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
let-7/9812921298m8hsa-let-7abrainUGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrainUGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrainUGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrainAGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrainUGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrainUGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brainUGAGGUAGUAAGUUGUAUUGUU
hsa-let-7gSZUGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrainUGAGGUAGUAGUUUGUGCUGU
miR-124.1140414111A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/506140414101Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-13750645070m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-142-5p278627921Ahsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-15/16/195/424/49750185024m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-1995561m8hsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-21450165022m8hsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-21814331439m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-26310431101Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-32576821Ahsa-miR-325CCUAGUAGGUGUCCAGUAAGUGU
miR-326390139071Ahsa-miR-326CCUCUGGGCCCUUCCUCCAG
miR-3314141420m8hsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-331135913651Ahsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-33513441350m8hsa-miR-335brainUCAAGAGCAAUAACGAAAAAUGU
miR-33913571363m8hsa-miR-339UCCCUGUCCUCCAGGAGCUCA
miR-361499049961Ahsa-miR-361brainUUAUCAGAAUCUCCAGGGGUAC
miR-410278827941Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-504132713341A,m8hsa-miR-504AGACCCUGGUCUGCACUCUAU
miR-539496549721A,m8hsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
miR-931793185m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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