Gene Page: CYP3A43
Summary ?
| GeneID | 64816 |
| Symbol | CYP3A43 |
| Synonyms | - |
| Description | cytochrome P450 family 3 subfamily A member 43 |
| Reference | MIM:606534|HGNC:HGNC:17450|Ensembl:ENSG00000021461|HPRD:05942|Vega:OTTHUMG00000156498 |
| Gene type | protein-coding |
| Map location | 7q21.1 |
| Pascal p-value | 0.707 |
| Fetal beta | -0.249 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG STEROID HORMONE BIOSYNTHESIS | 55 | 30 | All SZGR 2.0 genes in this pathway |
| KEGG LINOLEIC ACID METABOLISM | 29 | 16 | All SZGR 2.0 genes in this pathway |
| KEGG RETINOL METABOLISM | 64 | 37 | All SZGR 2.0 genes in this pathway |
| KEGG METABOLISM OF XENOBIOTICS BY CYTOCHROME P450 | 70 | 44 | All SZGR 2.0 genes in this pathway |
| KEGG DRUG METABOLISM CYTOCHROME P450 | 72 | 47 | All SZGR 2.0 genes in this pathway |
| KEGG DRUG METABOLISM OTHER ENZYMES | 51 | 27 | All SZGR 2.0 genes in this pathway |
| REACTOME BIOLOGICAL OXIDATIONS | 139 | 91 | All SZGR 2.0 genes in this pathway |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 51 | 34 | All SZGR 2.0 genes in this pathway |
| REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | 70 | 50 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 7Q21 Q22 AMPLICON | 76 | 33 | All SZGR 2.0 genes in this pathway |
| YANG MUC2 TARGETS DUODENUM 3MO DN | 23 | 14 | All SZGR 2.0 genes in this pathway |
| YANG MUC2 TARGETS DUODENUM 6MO DN | 21 | 12 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER CANCER DN | 540 | 340 | All SZGR 2.0 genes in this pathway |
| TAVAZOIE METASTASIS | 108 | 68 | All SZGR 2.0 genes in this pathway |
| CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN | 179 | 97 | All SZGR 2.0 genes in this pathway |
| WOO LIVER CANCER RECURRENCE DN | 80 | 54 | All SZGR 2.0 genes in this pathway |
| FEVR CTNNB1 TARGETS DN | 553 | 343 | All SZGR 2.0 genes in this pathway |