Gene Page: CDKL5

Summary
GeneID  6792
Symbol  CDKL5
Synonyms  ISSX|STK9
Description  cyclin-dependent kinase-like 5
See related  HGNC:11411|MIM:300203|Ensembl:ENSG00000008086|HPRD:02190|
Locus tag  RP1-245G19.3
Gene type  protein-coding
Map location  Xp22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
UTP60.910.88
TRIP40.900.88
WDR700.900.90
ZBED50.900.90
TRA2A0.900.88
ZNF1870.890.88
POLR3C0.890.89
CSTF30.890.88
MARK30.890.86
RAE10.890.88
Top 10 negatively co-expressed genes
MT-CO2-0.80-0.83
AF347015.27-0.80-0.83
AF347015.33-0.79-0.82
AF347015.31-0.78-0.82
AF347015.8-0.78-0.83
AF347015.15-0.78-0.83
MT-CYB-0.78-0.82
HLA-F-0.78-0.80
AF347015.2-0.77-0.85
TINAGL1-0.76-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008236serine-type peptidase activityIEAglutamate (GO term level: 6)-
GO:0004693cyclin-dependent protein kinase activityIEAneuron (GO term level: 8)-
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingIDA16935860 
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0046777protein amino acid autophosphorylationIDA16935860 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA16935860 
GO:0005737cytoplasmIDA18029348 
GO:0016020membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_UP 6238All SZGR genes in this pathway
HOEGERKORP_CD44_TARGETS_DIRECT_UP 2721All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_UP 225139All SZGR genes in this pathway
FIRESTEIN_PROLIFERATION 175125All SZGR genes in this pathway
CHANG_CYCLING_GENES 14883All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2 182102All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN 9156All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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