Gene Page: GALNT4

Summary ?
GeneID8693
SymbolGALNT4
SynonymsGALNAC-T4|GALNACT4
Descriptionpolypeptide N-acetylgalactosaminyltransferase 4
ReferenceMIM:603565|HGNC:HGNC:4126|Ensembl:ENSG00000257594|HPRD:09152|Vega:OTTHUMG00000166292
Gene typeprotein-coding
Map location12q21.33
eGeneMyers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DNM:Ambalavanan_2016Whole Exome SequencingThis dataset includes 20 de novo mutations detected in 17 COS probands.

Section I. Genetics and epigenetics annotation

@DNM table

GeneChromosomePositionRefAltTranscriptAA changeMutation typeSiftCG46TraitStudy
GALNT4chr1289917133GANM_001199781p.(=)synonymous SNVChildhood-onset schizophreniaDNM:Ambalavanan_2016

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs2052828chr1289888789GALNT486930cis
rs7960289chr1289890589GALNT486930.01cis
rs7310515chr1289899626GALNT486930cis
rs7310238chr1289899701GALNT486930cis
rs7299172chr1289899851GALNT486930cis
rs10777181chr1289908626GALNT486930cis
rs10777182chr1289908690GALNT486930cis
rs10745505chr1289910683GALNT486930.01cis
rs10858907chr1289934559GALNT486930.03cis
rs10858908chr1289934656GALNT486930.02cis
rs2052828chr1289888789GALNT486930.14trans
rs7310515chr1289899626GALNT486930.14trans
rs7310238chr1289899701GALNT486930.08trans
rs7299172chr1289899851GALNT486930.11trans
rs10777181chr1289908626GALNT486930.16trans
rs10777182chr1289908690GALNT486930.18trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
DYNC1LI10.940.93
CUL20.920.91
MRPL30.910.91
RAB1A0.910.91
HMGCLL10.910.90
STRAP0.900.89
FBXO30.900.90
AZIN10.900.89
PPHLN10.900.88
STX120.890.88
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MT-CO2-0.74-0.74
AF347015.33-0.74-0.74
AF347015.8-0.73-0.74
AF347015.2-0.72-0.75
FXYD1-0.72-0.75
AF347015.27-0.71-0.73
MT-CYB-0.71-0.72
AF347015.15-0.71-0.73
AF347015.31-0.71-0.72
AF347015.26-0.70-0.73

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG O GLYCAN BIOSYNTHESIS 3016All SZGR 2.0 genes in this pathway
IGARASHI ATF4 TARGETS DN 9065All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER LMP UP 265158All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER GRADES 1 2 UP 13784All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781465All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 17811082All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS DN 848527All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475313All SZGR 2.0 genes in this pathway
ZHENG FOXP3 TARGETS IN THYMUS UP 196137All SZGR 2.0 genes in this pathway
ENGELMANN CANCER PROGENITORS DN 7044All SZGR 2.0 genes in this pathway
VERHAAK GLIOBLASTOMA CLASSICAL 162122All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP A 898516All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658397All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP 289184All SZGR 2.0 genes in this pathway