Gene Page: TSPAN18

Summary ?
GeneID90139
SymbolTSPAN18
SynonymsTSPAN
Descriptiontetraspanin 18
ReferenceHGNC:HGNC:20660|Ensembl:ENSG00000157570|HPRD:17435|Vega:OTTHUMG00000163883
Gene typeprotein-coding
Map location11p11.2
Pascal p-value0.222
DMG1 (# studies)
eGeneCerebellum
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWAScatGenome-wide Association StudiesThis data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg139895191144820674TSPAN182.372E-4-0.4070.037DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs6687849chr1175904808TSPAN18901390.18trans
rs2502827chr1176044216TSPAN18901390.03trans
rs17572651chr1218943612TSPAN18901390.08trans
rs6753473chr226526418TSPAN18901390.01trans
rs17028363chr241913161TSPAN18901390.15trans
rs16829545chr2151977407TSPAN18901392.308E-30trans
rs16841750chr2158288461TSPAN18901393.988E-5trans
rs16863816chr2177292762TSPAN18901390.13trans
rs7584986chr2184111432TSPAN18901391.898E-4trans
rs6741060chr2217169088TSPAN18901390.15trans
rs10183246chr2237187882TSPAN18901390.11trans
rs9810143chr35060209TSPAN18901393.33E-5trans
rs6797307chr38601563TSPAN18901390.01trans
rs6773248chr3174790333TSPAN18901390.11trans
rs6797728chr3174790417TSPAN18901390.11trans
rs12642340chr435390674TSPAN18901390.13trans
rs17008119chr4125321425TSPAN18901390.06trans
rs7692715chr4125335209TSPAN18901390.01trans
rs4488887chr4177695833TSPAN18901390.12trans
rs10474151chr584286402TSPAN18901390.04trans
rs133604960TSPAN18901390trans
rs13191953chr624151042TSPAN18901390.14trans
rs12196880chr624313746TSPAN18901390.07trans
rs10806988chr624341768TSPAN18901390.12trans
rs16890367chr638078448TSPAN18901390trans
rs12706918chr780266147TSPAN18901390.06trans
rs6996695chr877540580TSPAN18901390.1trans
rs3118341chr925185518TSPAN18901390.01trans
rs9406868chr925223372TSPAN18901390.07trans
rs11139334chr984209393TSPAN18901390.02trans
rs2393316chr1059333070TSPAN18901390.01trans
rs17124813chr10110347464TSPAN18901390.06trans
rs7972699chr12105155290TSPAN18901390.17trans
rs7488439chr12105155814TSPAN18901390.05trans
rs17036489chr12105292283TSPAN18901390.02trans
rs16955618chr1529937543TSPAN18901391.787E-32trans
rs12914345chr1577670400TSPAN18901390.1trans
rs17711752chr1634436184TSPAN18901390.2trans
rs11873184chr181584081TSPAN18901390.01trans
rs7274477chr201676942TSPAN18901390.02trans
rs1041786chr2122617710TSPAN18901395.398E-7trans
rs16990575chrX32691327TSPAN18901390trans
rs16993189chrX144666166TSPAN18901390.17trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
LIU PROSTATE CANCER DN 481290All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE UP 423283All SZGR 2.0 genes in this pathway
WANG ESOPHAGUS CANCER VS NORMAL UP 12172All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR DN 428306All SZGR 2.0 genes in this pathway
SHEPARD CRUSH AND BURN MUTANT UP 197110All SZGR 2.0 genes in this pathway
SHEPARD BMYB MORPHOLINO UP 205126All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP 487303All SZGR 2.0 genes in this pathway
TOYOTA TARGETS OF MIR34B AND MIR34C 463262All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 142103All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069729All SZGR 2.0 genes in this pathway
MIKKELSEN NPC HCP WITH H3K4ME3 AND H3K27ME3 210148All SZGR 2.0 genes in this pathway
HOELZEL NF1 TARGETS UP 13993All SZGR 2.0 genes in this pathway