Gene Page: PTER
Summary ?
| GeneID | 9317 |
| Symbol | PTER |
| Synonyms | HPHRP|RPR-1 |
| Description | phosphotriesterase related |
| Reference | MIM:604446|HGNC:HGNC:9590|Ensembl:ENSG00000165983|HPRD:16061|Vega:OTTHUMG00000017737 |
| Gene type | protein-coding |
| Map location | 10p12 |
| Pascal p-value | 0.047 |
| Fetal beta | -2.47 |
| eGene | Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HYI | 0.82 | 0.73 |
| WDR34 | 0.81 | 0.69 |
| NME4 | 0.81 | 0.73 |
| MAD2L2 | 0.80 | 0.63 |
| STX10 | 0.80 | 0.66 |
| MDK | 0.79 | 0.64 |
| C19orf48 | 0.79 | 0.66 |
| ZNF784 | 0.78 | 0.69 |
| BCL7C | 0.78 | 0.69 |
| SNF8 | 0.78 | 0.65 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PLA2G4A | -0.43 | -0.52 |
| RAPGEF4 | -0.43 | -0.51 |
| RGS5 | -0.43 | -0.48 |
| AF347015.27 | -0.43 | -0.50 |
| ME1 | -0.42 | -0.47 |
| AF347015.31 | -0.42 | -0.49 |
| MT-CYB | -0.42 | -0.50 |
| OMG | -0.42 | -0.50 |
| C5orf53 | -0.41 | -0.45 |
| AF347015.33 | -0.41 | -0.48 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| BASAKI YBX1 TARGETS DN | 384 | 230 | All SZGR 2.0 genes in this pathway |
| UDAYAKUMAR MED1 TARGETS UP | 135 | 82 | All SZGR 2.0 genes in this pathway |
| LA MEN1 TARGETS | 24 | 15 | All SZGR 2.0 genes in this pathway |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | 584 | 395 | All SZGR 2.0 genes in this pathway |
| JIANG HYPOXIA NORMAL | 311 | 205 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
| LABBE WNT3A TARGETS DN | 97 | 53 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA C CLUSTER UP | 38 | 26 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA C UP | 47 | 29 | All SZGR 2.0 genes in this pathway |
| PIONTEK PKD1 TARGETS UP | 38 | 24 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN NPC ICP WITH H3K4ME3 | 445 | 257 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE EARLY LATE | 317 | 190 | All SZGR 2.0 genes in this pathway |
| KOHOUTEK CCNT1 TARGETS | 50 | 26 | All SZGR 2.0 genes in this pathway |