Gene Page: H2AFY

Summary
GeneID  9555
Symbol  H2AFY
Synonyms  H2A.y|H2A/y|H2AF12M|H2AFJ|MACROH2A1.1|mH2A1|macroH2A1.2
Description  H2A histone family, member Y
See related  HGNC:4740|MIM:610054|Ensembl:ENSG00000113648|HPRD:13624|
Locus tag  -
Gene type  protein-coding
Map location  5q31.3-q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
GCC20.900.86
MAPK90.900.89
EPS150.890.88
DNAJC270.890.88
SGTB0.890.86
B4GALT60.890.89
SAMD120.890.83
DDHD20.880.86
HOOK10.880.88
RIMS10.880.90
Top 10 negatively co-expressed genes
BCL7C-0.51-0.58
AC006276.2-0.49-0.49
NME4-0.48-0.57
SIGIRR-0.47-0.54
RPLP1-0.46-0.50
RPL36-0.45-0.51
RPL28-0.45-0.54
RPL23A-0.45-0.48
RPL35-0.45-0.50
RPL18-0.44-0.51
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingNAS9714746 
GO:0003682chromatin bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006334nucleosome assemblyNAS9714746 
GO:0007549dosage compensationIDA15053874 
GO:0016568chromatin modificationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001740Barr bodyIDA11331621 
GO:0000786nucleosomeNAS9714746 
GO:0000793condensed chromosomeIEA-
GO:0005634nucleusIEA-
GO:0005694chromosomeIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onsetCo-localizationBioGRID12419249 
SPOPTEF2speckle-type POZ protein-HPRD12183056 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
PID_ATF2_PATHWAY 5943All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP 305185All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_UP 316190All SZGR genes in this pathway
BIDUS_METASTASIS_UP 214134All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
RODRIGUES_NTN1_AND_DCC_TARGETS 3525All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM 15993All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER 10062All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_UP 256159All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_UP 266171All SZGR genes in this pathway
SWEET_KRAS_TARGETS_DN 6639All SZGR genes in this pathway
GOLDRATH_HOMEOSTATIC_PROLIFERATION 171102All SZGR genes in this pathway
PARK_HSC_VS_MULTIPOTENT_PROGENITORS_UP 1914All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP 180114All SZGR genes in this pathway
POS_RESPONSE_TO_HISTAMINE_UP 1310All SZGR genes in this pathway
POS_HISTAMINE_RESPONSE_NETWORK 3222All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
CHANGOLKAR_H2AFY_TARGETS_DN 4026All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_1_UP 194133All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
HUANG_GATA2_TARGETS_UP 14996All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-148/1521841901Ahsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-411227233m8hsa-miR-411AACACGGUCCACUAACCCUCAGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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