Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 476 literature records
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Entrez ID
Description
3622
"Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor."
8678
"Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21."
1801
"Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells."
27132
"Since these domains have been found in several membrane-binding proteins involved in different intracellular processes, copine VII was viewed as a potential tumor suppressor gene."
2134
"Recently, the EXTL1 gene, a member of the EXT tumor suppressor gene family, has been mapped to 1p36, a chromosome region which is frequently implicated in a wide variety of malignancies, including breast carcinoma, colorectal cancer and neuroblastoma. "
3621
Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene.
274
Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity.
672
Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.
5325
"Zac1 (Lot1), a potential tumor suppressor gene, and the gene for epsilon-sarcoglycan are maternally imprinted genes: identification by a subtractive screen of novel uniparental fibroblast lines."
23136
"Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas."
634
"C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers."
6477
Lack of somatic mutation in the coding sequence of SIAH1 in tumors hemizygous for this candidate tumor suppressor gene.
1801
"Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor."
10641
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
11186
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
11334
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
51364
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
7869
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.
7982
Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31.
11186
"Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers."
8678
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function.
5325
Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities.
11186
"The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis."
9077
Genomic structure and promoter characterization of an imprinted tumor suppressor gene ARHI.
5655
Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue.
6422
WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type.
11334
Overexpression of candidate tumor suppressor geneFUS1 isolated from the 3p21.3 homozygous deletionregion leads to G1 arrest and growth inhibition oflung cancer cells.
112464
Human SRBC is located within the 11p15.5-p15.4 tumor suppressor region and is inactivated in breast and lung cancers.
7799
"Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily."
27086
The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
672
The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity.
9538
"Our data represent the first evidence of alterations in the PIG8 gene in human malignancies, a finding that substantiates its role as a potential tumour suppressor gene as suggested by its involvement in p53-induced apoptosis."
10664
"observations suggest that CTCF may represent a novel tumor suppressor gene that displays tumor-specific ""change of function"" rather than complete ""loss of function"""
5268
"Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen."
7832
"The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene."
5728
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.
2706
Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer.
11186
RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1.
5915
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer.
10641
Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo.
8838
"WISP3 acts as a tumor suppressor gene in the breast. Loss of WISP3 expression contributes to the phenotype of IBC by regulating tumor cell growth, invasion and angiogenesis."
148252
Rig a novel Ras-related protein and potential neural tumor suppressor (RIG)
6794
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma.
863
CBFA2T3 (MTG16) is a putative breast tumor suppressor gene from the breast cancer loss of heterozygosity region at 16q24.3.
5728
Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer.
863
"Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes."
7020
Results indicate that the tumor suppressor activity of AP2alpha is mediated through a direct interaction with p53.
688
A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer.
23221
"DBC2, a candidate for a tumor suppressor gene involved in breast cancer."
9353
"SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers."
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