DegronMD

Description:

KLHL2 and KLHL3 binding degron An Acidic degron motif present in wnk kinases necessary to interact with kelch domain of KLHL2 and KLHL3 proteins for efficient ubiquitination degradation.

Uniprot ID	Degron Hit	Degron Class	Location	E3 ligase	Source protein	Detail
Q96J92	EPEEPEADQH	DEG_Kelch_KLHL3_1	557:566	CUL3,KLHL3,KLHL2	Serine/threonine-protein kinase WNK4	Detail..
Q9BYP7	ECEETEVDQH	DEG_Kelch_KLHL3_1	537:546	CUL3,KLHL3,KLHL2	Serine/threonine-protein kinase WNK3	Detail..
Q9H4A3	EPEEPEADQH	DEG_Kelch_KLHL3_1	628:637	CUL3,KLHL3,KLHL2	Serine/threonine-protein kinase WNK1	Detail..
Q9Y3S1	EPEEPEADQH	DEG_Kelch_KLHL3_1	588:597	CUL3,KLHL3,KLHL2	Serine/threonine-protein kinase WNK2	Detail..

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Class: DEG_Kelch_KLHL3_1

Description:

All proteins holding degrons of class DEG_Kelch_KLHL3_1