DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
ARSTT
Uniprot ID:
A6NDY2
Source protein:
Putative protein FAM90A10
Source gene:
FAM90A10
Class:
DEG_SPOP_SBC_1
Location:
54:58
E3 ligase:
SPOP
DEGRON score:
0.5218
ASA_SCORE:
78.14
COIL:
0.8034
CONS_SCORE:
0.6107
DSS_SCORE:
0.1452
HELIX:
0.0916
FCONS_SCORE:
0.7996
RIG_SCORE:
0.7498
Degron related mutations and impact score
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Mutation
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Degron
Degron class
Impact score
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Drug responses associated with FAM90A10 mutations
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Mutation (In Degron?)
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All proteins holding degron of ARSTT
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9Y2N7
Hypoxia-inducible factor 3-alpha
DEG_SPOP_SBC_1
8:12
ARSTT
SPOP
0.7168
More...
Q9UKN1
Mucin-12
DEG_SPOP_SBC_1
818:822
ARSTT
SPOP
0.6179
More...
Q9UKN1
Mucin-12
DEG_SPOP_SBC_1
927:931
ARSTT
SPOP
0.959
More...
O94964
Protein SOGA1
DEG_SPOP_SBC_1
1236:1240
ARSTT
SPOP
0.9985
More...
A6NDY2
Putative protein FAM90A10
DEG_SPOP_SBC_1
54:58
ARSTT
SPOP
0.5218
More...
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