DegronMD - Q9UKN1(MUC12)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T4982S	TCGA-BK-A4ZD	UCEC	TCGA	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation altering degron motif	0.7116
p.F4853L	TCGA-LN-A9FP	ESCA	TCGA	AESTT	DEG_SPOP_SBC_1	4852:4856	Mutation altering degron motif	0.6981
p.S4924F	TCGA-LN-A9FP	ESCA	TCGA	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.3056
p.T4406S	DO639	BLCA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation altering degron motif	0.6005
p.S715F	DO225334	BRCA	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.25
p.T760K	DO225390	BRCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.1944
p.T760K	DO225390	BRCA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1944
p.T793P	DO228483	BRCA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	ACH-000247	Gastric Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	ACH-000478	Liver Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	ACH-001655	Endometrial/Uterine Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	OCUM-1	stomach	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	KP-N-YN	autonomic ganglia	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	SKN	soft tissue	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T793P	SNU-387	liver	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.T755S	DO228483	BRCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.6005
p.T755S	DO229010	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.6005
p.T755S	DO229003	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.6005
p.T755S	DO229005	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.6005
p.T755S	DO234285	ESAD	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.6005
p.T755S	DO52365	LUSC	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.6005
p.S4980L	DO5738	BRCA	ICGC	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation rewiring degron network	0.3056
p.P475T	DO222827	BTCA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0833
p.P475T	DO229061	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0833
p.A4923V	DO50090	COAD	ICGC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.2778
p.A4923V	ACH-001329	Brain Cancer	CCLE	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.2778
p.P791H	DO7801	COAD	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.0833
p.P5083Q	DO230315	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	5092:5096	Mutation rewiring degron network	0.0833
p.T3425R	DO224668	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.T3425R	DO229013	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.T3425R	DO229505	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.T3425R	DO229051	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1944
p.K3247I	DO224689	COCA	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO228005	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO228008	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO51028	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO228985	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO224541	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO52342	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.K3247I	DO52346	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation substituting flanking lysine	0.25
p.S4524L	DO222794	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1389
p.S4524L	DO229242	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1389
p.R928H	DO222884	COCA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7133
p.R928H	DO229032	LICA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7133
p.R928H	DO232761	PBCA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7133
p.S1884L	DO222881	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.S1884L	DO229010	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.S1884L	DO229013	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.S1884L	DO229016	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.S1884L	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.S1884L	DO229005	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.R1308P	DO229010	COCA	ICGC	VYSSS	DEG_SPOP_SBC_1	1303:1307	Mutation rewiring degron network	0.3056
p.R1308P	DO229013	COCA	ICGC	VYSSS	DEG_SPOP_SBC_1	1303:1307	Mutation rewiring degron network	0.3056
p.R1308P	DO229016	COCA	ICGC	VYSSS	DEG_SPOP_SBC_1	1303:1307	Mutation rewiring degron network	0.3056
p.L1878F	DO229010	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.3056
p.L1878F	DO229013	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.3056
p.L1878F	DO229016	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.3056
p.L1878F	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.3056
p.L1878F	DO229005	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.3056
p.L1878F	DO229167	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.3056
p.M749T	DO229010	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.M749T	DO229013	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.M749T	DO229016	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.M749T	DO229003	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.M749T	DO229005	COCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.T1866I	DO229010	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.T1866I	DO229013	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.T1866I	DO229016	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.T1866I	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.T1866I	DO229005	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.T1866I	DO229024	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.T1866I	DO229218	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1389
p.R1880H	DO229010	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.25
p.R1880H	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.25
p.R1880H	DO229005	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.25
p.R1880H	DO52365	LUSC	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.25
p.R1880H	DO52341	LUSC	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.25
p.H1814R	DO229010	COCA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.H1814R	DO229013	COCA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.H1814R	DO229016	COCA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.H1814R	DO229003	COCA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.H1814R	DO229005	COCA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.H1814R	DO234285	ESAD	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.H1814R	DO229006	LICA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.G625D	DO229013	COCA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6087
p.G625D	ACH-001786	Colon/Colorectal Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6087
p.G625D	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6087
p.G625D	LU-65	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6087
p.G625D	NCC010	kidney	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6087
p.G625D	LC4-1	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6087
p.S707F	DO229016	COCA	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.3056
p.G1764R	DO229016	COCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation altering degron motif	0.6457
p.G1764R	DO223069	ESCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation altering degron motif	0.6457
p.T4470I	DO229016	COCA	ICGC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.1667
p.T4470I	DO229048	LICA	ICGC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.1667
p.T931N	DO229016	COCA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7055
p.R4713H	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.25
p.R4713H	DO51005	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.25
p.S4717L	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1389
p.S4717L	DO50979	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1389
p.S4717L	DO229192	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1389
p.L4711F	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.3056
p.L4711F	DO51005	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.3056
p.T4699I	DO229003	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1389
p.T4699I	DO229005	COCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1389
p.T4699I	DO229221	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1389
p.P4507R	DO50441	ESAD	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1667
p.R1825H	DO50334	ESAD	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.3056
p.T920M	DO234389	ESAD	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1389
p.T920M	SJSA-1	bone	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1389
p.R770H	DO223058	ESCA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.3056
p.R770H	DO51527	PACA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.3056
p.R770H	COR-L95	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.3056
p.T455I	DO222509	ESCA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.1389
p.S4937T	DO222518	ESCA	ICGC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.1111
p.P800L	DO222575	ESCA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7582
p.P800L	DO229053	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7582
p.P800L	DO229055	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7582
p.Q4935H	DO233270	GACA	ICGC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.1667
p.R770C	DO233650	GACA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.3056
p.R770C	DO52692	MALY	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.3056
p.S820F	DO233764	GACA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation altering degron motif	0.7982
p.E4147D	DO44525	KIRP	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1944
p.H469R	DO228005	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.25
p.H469R	DO229051	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.25
p.H469R	DO229055	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.25
p.H469R	DO229088	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.25
p.S1057P	DO229348	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	1066:1070	Mutation rewiring degron network	0.0833
p.S1057P	DO50985	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	1066:1070	Mutation rewiring degron network	0.0833
p.S1057P	DO52365	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	1066:1070	Mutation rewiring degron network	0.0833
p.T4214A	DO229348	LAML	ICGC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.25
p.T4214A	DO229348	LAML	ICGC	PASST	DEG_SPOP_SBC_1	4208:4212	Mutation rewiring degron network	0.2778
p.T4214A	DO228974	LICA	ICGC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.25
p.T4214A	DO228974	LICA	ICGC	PASST	DEG_SPOP_SBC_1	4208:4212	Mutation rewiring degron network	0.2778
p.S4607T	DO229353	LAML	ICGC	APSTT	DEG_SPOP_SBC_1	4594:4598	Mutation rewiring degron network	0.0833
p.G3293S	DO229486	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO228912	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO229053	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO229062	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO229006	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO229218	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO229232	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.G3293S	DO229089	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.5882
p.T3286M	DO229505	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.1667
p.T4508R	DO229505	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1944
p.T2739I	DO227501	LAML	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.T2739I	DO227504	LAML	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.T2739I	DO51004	LAML	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.T2739I	DO224589	LUSC	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.T2739I	DO224613	LUSC	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.T2739I	DO229208	THCA	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.T2739I	DO229213	THCA	ICGC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.3056
p.F4262L	DO227504	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.2778
p.F4262L	DO51037	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.2778
p.F4262L	DO229058	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.2778
p.F4262L	DO224576	LUSC	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.2778
p.F4262L	DO224619	LUSC	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.2778
p.F4262L	DO229227	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.2778
p.T3599M	DO50998	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3594:3598	Mutation rewiring degron network	0.3056
p.T3599M	DO50980	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	3594:3598	Mutation rewiring degron network	0.3056
p.T3599M	DO52391	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	3594:3598	Mutation rewiring degron network	0.3056
p.E2549K	DO51023	LAML	ICGC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1667
p.E2549K	DO228950	LICA	ICGC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1667
p.P2321A	DO51015	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	2315:2319	Mutation rewiring degron network	0.2778
p.P2321A	DO229264	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	2315:2319	Mutation rewiring degron network	0.2778
p.F1622L	DO51002	LAML	ICGC	ASSTT	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.2778
p.G2029V	DO231188	LAML	ICGC	PGSTT	DEG_SPOP_SBC_1	2037:2041	Mutation rewiring degron network	0.1111
p.P701S	DO228220	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.1389
p.P701S	DO228960	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.1389
p.S817C	DO228634	LICA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.3056
p.F3179L	DO228912	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.2778
p.T1581I	DO228923	LICA	ICGC	LTPASS	DEG_SCF_FBW7_1	1566:1571	Mutation rewiring degron network	0.0556
p.T1581I	DO228923	LICA	ICGC	PASST	DEG_SPOP_SBC_1	1568:1572	Mutation rewiring degron network	0.0833
p.T1581I	ACH-000467	Colon/Colorectal Cancer	CCLE	LTPASS	DEG_SCF_FBW7_1	1566:1571	Mutation rewiring degron network	0.0556
p.T1581I	ACH-000467	Colon/Colorectal Cancer	CCLE	PASST	DEG_SPOP_SBC_1	1568:1572	Mutation rewiring degron network	0.0833
p.A3065S	DO228923	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3069:3073	Mutation rewiring degron network	0.2222
p.T4463I	DO228943	LICA	ICGC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation altering degron motif	0.7078
p.I816F	DO228943	LICA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.2778
p.I816F	DO229053	LICA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.2778
p.T3423I	DO228945	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.T3423I	DO229052	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.T3423I	DO229058	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.M262T	DO228945	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.1667
p.M262T	DO231475	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.1667
p.M262T	LXF-289	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.1667
p.A2620S	DO228948	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	2623:2627	Mutation rewiring degron network	0.25
p.W4226C	DO228948	LICA	ICGC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.0556
p.P3420R	DO228950	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.0556
p.A4436T	DO228967	LICA	ICGC	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation rewiring degron network	0.0556
p.A4436T	DO222749	MELA	ICGC	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation rewiring degron network	0.0556
p.L688V	DO228967	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.2222
p.L688V	DO229056	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.2222
p.Q1523E	DO228960	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	1512:1516	Mutation rewiring degron network	0.1389
p.A1574T	DO228991	LICA	ICGC	LTPASS	DEG_SCF_FBW7_1	1566:1571	Mutation rewiring degron network	0.25
p.A1574T	DO228991	LICA	ICGC	PASST	DEG_SPOP_SBC_1	1568:1572	Mutation rewiring degron network	0.2778
p.A1574T	DO229040	LICA	ICGC	LTPASS	DEG_SCF_FBW7_1	1566:1571	Mutation rewiring degron network	0.25
p.A1574T	DO229040	LICA	ICGC	PASST	DEG_SPOP_SBC_1	1568:1572	Mutation rewiring degron network	0.2778
p.G1764V	DO229019	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation altering degron motif	0.6421
p.G955C	DO229028	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	954:958	Mutation altering degron motif	0.6489
p.G625C	DO229026	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6489
p.K629T	DO229030	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.3056
p.K629T	DO229052	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.3056
p.K629T	DO229056	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.3056
p.T1426A	DO229030	LICA	ICGC	PTTPSLS	DEG_SCF_FBW7_1	1431:1437	Mutation rewiring degron network	0.1944
p.A3306T	DO229030	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.0556
p.A3306T	DO229056	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.0556
p.S1502I	DO229036	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	1512:1516	Mutation rewiring degron network	0.0556
p.S614I	DO229037	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.0556
p.G1075V	DO229037	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	1066:1070	Mutation rewiring degron network	0.1944
p.R4465L	DO229037	LICA	ICGC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.3056
p.V3300F	DO229041	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.2222
p.H3371R	DO229042	LICA	ICGC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.H3371R	DO46771	PAEN	ICGC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.S807R	DO229050	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.P4258A	DO229052	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.1667
p.S4415Y	DO229052	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1111
p.S4415Y	DO229063	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1111
p.S4415Y	DO229257	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1111
p.A260G	DO229052	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.1111
p.A260G	DO231475	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.1111
p.T4506I	DO229052	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1389
p.T4506I	DO229053	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1389
p.T4506I	DO229063	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1389
p.G3378S	DO229051	LICA	ICGC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation altering degron motif	0.5882
p.R3437H	DO229051	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.25
p.R3437H	DO229057	LICA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.25
p.R3437H	NCI-H1963	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.25
p.R3437H	TE-441-T	soft tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.25
p.Q4163E	DO229056	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1389
p.Q4163E	DO229061	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1389
p.Q4163E	DO229062	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1389
p.T1230A	DO229055	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.2778
p.L4933P	DO229058	LICA	ICGC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.2222
p.P4413Q	DO229057	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1667
p.P4413Q	DO229060	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1667
p.Y720S	DO229057	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.1111
p.S4158L	DO229057	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.2778
p.S4158L	DO229062	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.2778
p.E4414Q	DO229061	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1389
p.E4414Q	DO229060	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.1389
p.I811T	DO229063	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1389
p.I811T	DO229063	LICA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.1389
p.G3293D	DO229063	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6087
p.S270I	DO229006	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation altering degron motif	0.7341
p.V4244F	DO229008	LICA	ICGC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.2222
p.K1690I	DO229004	LICA	ICGC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation substituting flanking lysine	0.25
p.K1690I	DO229268	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation substituting flanking lysine	0.25
p.K1690I	DO229216	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation substituting flanking lysine	0.25
p.P812Q	DO50889	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1111
p.P812Q	DO50889	LICA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.1667
p.G4988S	DO45181	LIRI	ICGC	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation rewiring degron network	0.25
p.H815N	DO230929	LUSC	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.25
p.H815N	DO224572	LUSC	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.25
p.G4069C	DO230940	LUSC	ICGC	PTTPSLS	DEG_SCF_FBW7_1	4071:4077	Mutation rewiring degron network	0.2778
p.G4069C	DO224584	LUSC	ICGC	PTTPSLS	DEG_SCF_FBW7_1	4071:4077	Mutation rewiring degron network	0.2778
p.G1772A	DO224544	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation rewiring degron network	0.1944
p.G1772A	DO231014	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation rewiring degron network	0.1944
p.T3138I	DO224610	LUSC	ICGC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.0556
p.T3138I	DO224610	LUSC	ICGC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0833
p.T3138I	ACH-000467	Colon/Colorectal Cancer	CCLE	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.0556
p.T3138I	ACH-000467	Colon/Colorectal Cancer	CCLE	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0833
p.S4238G	DO224624	LUSC	ICGC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation altering degron motif	0.6993
p.T2042M	DO52359	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	2037:2041	Mutation rewiring degron network	0.3056
p.S4142I	DO231031	LUSC	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.0556
p.P808S	DO231043	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2222
p.P808S	DO231043	LUSC	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.0556
p.R928C	DO52674	MALY	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.719
p.A274T	DO220856	MELA	ICGC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.P452S	DO220874	MELA	ICGC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0556
p.G772R	DO220877	MELA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.25
p.S757L	DO220877	MELA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.S757L	DO220877	MELA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1111
p.S757L	DO47268	SKCM	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.S757L	DO47268	SKCM	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1111
p.S757L	NCI-H835	lung	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.S757L	NCI-H835	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1111
p.P4503S	DO220899	MELA	ICGC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.0556
p.S4452L	DO220903	MELA	ICGC	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation rewiring degron network	0.2778
p.S4452L	DO220903	MELA	ICGC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.1111
p.G1827E	DO220907	MELA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.25
p.S636F	DO220913	MELA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1111
p.S636F	DO35721	PBCA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1111
p.E619K	DO222395	MELA	ICGC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1944
p.P718L	DO222557	MELA	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.1667
p.S929F	DO222653	MELA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.9093
p.T821P	DO222702	MELA	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation altering degron motif	0.8142
p.L934F	DO222875	MELA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.25
p.T684I	DO222837	MELA	ICGC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7078
p.T1830I	DO49135	PACA	ICGC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.1667
p.A765D	DO35550	PBCA	ICGC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.7793
p.A919T	DO232761	PBCA	ICGC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.A919T	LN-18	central nervous system	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.A919T	IGR-1	skin	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.A919T	H2595	pleura	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.A919T	H2869	pleura	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.A4241S	DO232224	PBCA	ICGC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.3056
p.S963I	DO232555	PBCA	ICGC	PGSTT	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1944
p.G2615V	DO232519	PBCA	ICGC	PGSTT	DEG_SPOP_SBC_1	2623:2627	Mutation rewiring degron network	0.1111
p.V751I	DO232519	PBCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7076
p.V751I	DO229542	UTCA	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7076
p.P2795A	DO232532	PBCA	ICGC	PGSTT	DEG_SPOP_SBC_1	2789:2793	Mutation rewiring degron network	0.2778
p.P2795A	KASUMI-1	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	2789:2793	Mutation rewiring degron network	0.2778
p.T1236I	DO232675	PBCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation altering degron motif	0.7078
p.Q3716E	DO232681	PBCA	ICGC	PGSTT	DEG_SPOP_SBC_1	3706:3710	Mutation rewiring degron network	0.1667
p.T3241A	DO36556	READ	ICGC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.3056
p.S1747A	DO36556	READ	ICGC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation rewiring degron network	0.1111
p.S5104F	DO218914	SKCA	ICGC	PASSS	DEG_SPOP_SBC_1	5092:5096	Mutation rewiring degron network	0.1111
p.S1241I	DO218900	SKCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.1944
p.G4862S	DO218900	SKCA	ICGC	AESTT	DEG_SPOP_SBC_1	4852:4856	Mutation rewiring degron network	0.1667
p.G4862S	ACH-000796	Ovarian Cancer	CCLE	AESTT	DEG_SPOP_SBC_1	4852:4856	Mutation rewiring degron network	0.1667
p.S4142N	DO37409	SKCM	ICGC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.0556
p.H4447Y	DO37432	SKCM	ICGC	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation altering degron motif	0.6118
p.E719K	DO37440	SKCM	ICGC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.1389
p.G1736S	DO229181	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation altering degron motif	0.5882
p.L4440I	DO229259	THCA	ICGC	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation rewiring degron network	0.1667
p.P1238A	DO229272	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.2778
p.T4701R	DO229272	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1944
p.T4701R	DO229227	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1944
p.T1868R	DO229216	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	1873:1877	Mutation rewiring degron network	0.1944
p.R2531G	DO229229	THCA	ICGC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1111
p.F4704I	DO229221	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.2778
p.S4707R	DO229221	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation altering degron motif	0.6316
p.K4330I	DO229248	THCA	ICGC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation substituting flanking lysine	0.25
p.A3430P	DO229242	THCA	ICGC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation altering degron motif	0.6392
p.S809R	DO42400	UCEC	ICGC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation blocking phosphorylation signal	0.6389
p.S809R	DO42400	UCEC	ICGC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation blocking phosphorylation signal	0.5278
p.A747S	DO41199	UCEC	ICGC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2222
p.T4454P	SIDM02054	Esophageal Carcinoma	GDSC	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation rewiring degron network	0.2222
p.T4454P	SIDM02054	Esophageal Carcinoma	GDSC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.1667
p.G812S	SIDM01269	Esophageal Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.1111
p.G812S	SIDM01269	Esophageal Carcinoma	GDSC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.1667
p.R1582Q	SIDM01288	Colorectal Carcinoma	GDSC	PASST	DEG_SPOP_SBC_1	1568:1572	Mutation rewiring degron network	0.0556
p.S3584T	SIDM01943	Colorectal Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3594:3598	Mutation rewiring degron network	0.0556
p.T1509I	SIDM01308	Esophageal Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1512:1516	Mutation rewiring degron network	0.25
p.P746L	SIDM01313	Colorectal Carcinoma	GDSC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.1944
p.T2549A	SIDM00615	Hepatocellular Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1667
p.T2549A	SIDM00193	Colorectal Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1667
p.T2549A	SIDM00498	Colorectal Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1667
p.G3241R	SIDM00545	Melanoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.3056
p.G3241R	Mewo	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.3056
p.G4324E	SIDM00545	Melanoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.3056
p.G4324E	Mewo	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.3056
p.P4198L	SIDM00857	Melanoma	GDSC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.1111
p.P4198L	SIDM00857	Melanoma	GDSC	PASST	DEG_SPOP_SBC_1	4208:4212	Mutation rewiring degron network	0.0556
p.P4198L	G-361	skin	COSMIC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.1111
p.P4198L	G-361	skin	COSMIC	PASST	DEG_SPOP_SBC_1	4208:4212	Mutation rewiring degron network	0.0556
p.S3226L	SIDM00222	Mesothelioma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	SIDM01004	Chronic Myelogenous Leukemia	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	SIDM00103	Mesothelioma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	SIDM00898	Breast Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	SIDM00438	B-Lymphoblastic Leukemia	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	MPP-89	pleura	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	AU565	breast	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	KCL-22	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	MN-60	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.S3226L	H2373	pleura	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.0556
p.A3182E	SIDM01095	Rhabdomyosarcoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.7701
p.T807M	SIDM00611	Kidney Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00602	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM01005	Acute Myeloid Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00569	Osteosarcoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00687	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00487	Colorectal Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00564	Ovarian Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00574	Glioblastoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00280	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00373	Endometrial Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00579	Neuroblastoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.T807M	SIDM00435	Acute Myeloid Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.25
p.S767P	SIDM01103	Squamous Cell Lung Carcinoma	GDSC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.6752
p.S767P	SK-MES-1	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.6752
p.P1229A	SIDM01117	Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.25
p.L4920F	SIDM01117	Small Cell Lung Carcinoma	GDSC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.1944
p.A622T	SIDM00411	Pancreatic Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.2778
p.A622T	SIDM00599	Osteosarcoma	GDSC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.2778
p.A622T	YAPC	pancreas	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.2778
p.A622T	HuO9	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.2778
p.P1693R	SIDM01245	T-Lymphoblastic Leukemia	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation rewiring degron network	0.0556
p.P1693R	BE-13	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation rewiring degron network	0.0556
p.P4718S	SIDM01126	Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1111
p.P4718S	SIDM00846	Cervical Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1111
p.P4718S	SIDM00633	Breast Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.1111
p.P3233H	SIDM00082	Melanoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.25
p.P3233H	SK-MEL-2	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.25
p.P458T	SIDM00120	Prostate Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.2222
p.P458T	DU-145	prostate	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.2222
p.T4144I	SIDM00981	B-Cell Non-Hodgkin's Lymphoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1111
p.T4676N	SIDM00367	Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4677:4681	Mutation rewiring degron network	0.3056
p.T4676N	SBC-3	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4677:4681	Mutation rewiring degron network	0.3056
p.T4236N	SIDM00291	Melanoma	GDSC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation altering degron motif	0.7055
p.T4236N	HMV-II	skin	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation altering degron motif	0.7055
p.R3239C	SIDM00087	Plasma Cell Myeloma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.8301
p.R3239C	SIDM00694	Other Solid Cancers	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.8301
p.R3239C	SIDM00710	Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.8301
p.R3239C	HUTU-80	small intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.8301
p.R3239C	RPMI-8226	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.8301
p.R3239C	NCI-H2081	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.8301
p.F4329L	SIDM00741	Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.1667
p.F4329L	NCI-H1694	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.1667
p.V2738I	SIDM01259	B-Lymphoblastic Leukemia	GDSC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation altering degron motif	0.7076
p.H2029N	SIDM00188	Kidney Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	2037:2041	Mutation rewiring degron network	0.1111
p.H2029N	SIDM01711	Non-Cancerous	GDSC	PGSTT	DEG_SPOP_SBC_1	2037:2041	Mutation rewiring degron network	0.1111
p.S266T	SIDM00860	Head and Neck Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.S4711C	SIDM00834	Colorectal Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.3056
p.S4711C	SIDM00046	Non-Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.3056
p.S4711C	SIDM00688	B-Cell Non-Hodgkin's Lymphoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4706:4710	Mutation rewiring degron network	0.3056
p.R4196S	SIDM00353	Other Sarcomas	GDSC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.0556
p.R4196S	RKN	ovary	COSMIC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.0556
p.V5090I	SIDM00122	Breast Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	5092:5096	Mutation rewiring degron network	0.2778
p.L791V	SIDM00474	Ovarian Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.0833
p.T3291N	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.3056
p.T2728A	SIDM01099	Neuroblastoma	GDSC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.1667
p.T2728A	SK-N-FI	autonomic ganglia	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.1667
p.T2736I	SIDM01099	Neuroblastoma	GDSC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation altering degron motif	0.7078
p.T2736I	SK-N-FI	autonomic ganglia	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation altering degron motif	0.7078
p.F2551S	SIDM00998	Glioblastoma	GDSC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation blocking phosphorylation signal	0.5556
p.F2551S	8-MG-BA	central nervous system	COSMIC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation blocking phosphorylation signal	0.5556
p.E476K	SIDM00650	Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0556
p.E476K	SIDM01681	Non-Cancerous	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0556
p.T759R	SIDM01120	Other Solid Cancers	GDSC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2222
p.T759R	SIDM01120	Other Solid Cancers	GDSC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1667
p.T759R	SK-MEL-2	skin	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2222
p.T759R	SK-MEL-2	skin	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1667
p.G4318S	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.3056
p.G4318S	KYSE-510	oesophagus	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.3056
p.S459L	SIDM00708	Non-Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.25
p.S459L	NCI-H2087	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.25
p.V462D	SIDM00092	Ovarian Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7785
p.V462D	OVCAR-4	ovary	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7785
p.A776T	SIDM01060	Melanoma	GDSC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.A776T	SIDM00519	Mesothelioma	GDSC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.A776T	SIDM00100	Mesothelioma	GDSC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.A776T	H2869	pleura	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.A776T	H2595	pleura	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.A776T	LN-18	central nervous system	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.A776T	IGR-1	skin	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.R1682H	SIDM00687	Gastric Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation altering degron motif	0.8244
p.D464G	SIDM00027	Kidney Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7198
p.D464G	SK-NEP-1	kidney	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7198
p.T466M	SIDM00402	Bladder Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7423
p.T466M	RT-112	urinary tract	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7423
p.T2550N	SIDM00358	Gastric Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1389
p.T2550N	SIDM00054	Pancreatic Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1389
p.T2550N	PL18	pancreas	COSMIC	PATTT	DEG_SPOP_SBC_1	2539:2543	Mutation rewiring degron network	0.1389
p.G3178S	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.25
p.G3178S	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.25
p.G3178S	SIDM00930	Osteosarcoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.25
p.G3178S	HCE-4	oesophagus	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.25
p.P3187L	SIDM00681	Colorectal Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.2778
p.P3187L	SIDM01641	Non-Cancerous	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.2778
p.S266C	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.S266C	SIDM00672	Hepatocellular Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.S266C	SIDM00032	Bladder Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.P4416S	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.0833
p.T3173A	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.1111
p.T3173A	H513	pleura	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.1111
p.S704G	SIDM00505	Pancreatic Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.2222
p.S704G	MIA-PaCa-2	pancreas	COSMIC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.2222
p.S704G	HSC-39	stomach	COSMIC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.2222
p.S1669L	SIDM00893	Breast Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation rewiring degron network	0.0556
p.R1133C	SIDM00493	Other Solid Cancers	GDSC	PASST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.1389
p.R1133C	NCI-H292	lung	COSMIC	PASST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.1389
p.W4332G	SIDM00958	Chronic Myelogenous Leukemia	GDSC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.0833
p.W4332G	CML-T1	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.0833
p.G924S	SIDM00214	Colorectal Carcinoma	GDSC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.25
p.G924S	SNU-407	large intestine	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.25
p.T4235A	SIDM00214	Colorectal Carcinoma	GDSC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.3056
p.T4235A	SNU-407	large intestine	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.3056
p.A454D	SIDM00758	Non-Small Cell Lung Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.1111
p.A454D	NCI-H1993	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.1111
p.E806G	SIDM00131	Glioma	GDSC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2778
p.E806G	CCF-STTG1	central nervous system	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2778
p.G3178D	SIDM00567	Other Solid Cancers	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.25
p.G3178D	ONS-76	central nervous system	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.25
p.G4072A	SIDM01066	Melanoma	GDSC	PTTPSLS	DEG_SCF_FBW7_1	4071:4077	Mutation altering degron motif	0.754
p.G4072A	IGR-37	skin	COSMIC	PTTPSLS	DEG_SCF_FBW7_1	4071:4077	Mutation altering degron motif	0.754
p.M475V	SIDM00609	Kidney Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0833
p.M475V	KMRC-20	kidney	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.0833
p.R627H	SIDM00521	Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.8244
p.R627H	COR-L95	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.8244
p.T3237A	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.7139
p.T3237A	NCI-H2172	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.7139
p.S2737L	SIDM00793	Burkitt's Lymphoma	GDSC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation altering degron motif	0.7667
p.S2737L	EB-3	haematopoietic and lymphoid tissue	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation altering degron motif	0.7667
p.S614L	SIDM01133	Other Solid Cancers	GDSC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.0556
p.S614L	NCI-H835	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.0556
p.S4331R	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.1111
p.S4331R	NCI-H1573	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.1111
p.D5093N	SIDM00749	Non-Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	5092:5096	Mutation altering degron motif	0.6932
p.D5093N	NCI-H1573	lung	COSMIC	PASSS	DEG_SPOP_SBC_1	5092:5096	Mutation altering degron motif	0.6932
p.T1673R	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation rewiring degron network	0.1667
p.T1673R	SIDM00954	Breast Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation rewiring degron network	0.1667
p.T1673R	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation rewiring degron network	0.1667
p.D3172N	SIDM00954	Breast Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.0833
p.R965C	SIDM00999	Bladder Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1389
p.E4243Q	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.25
p.E4243Q	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.25
p.E4243D	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.25
p.E4243D	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.25
p.S3176T	SIDM00534	Colorectal Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.1944
p.S3176T	HT-115	large intestine	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.1944
p.Q4323H	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.7582
p.T633R	SIDM00233	T-Lymphoblastic Leukemia	GDSC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1944
p.T633R	ATN-1	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1944
p.S2036N	SIDM00150	Colorectal Carcinoma	GDSC	PGSTT	DEG_SPOP_SBC_1	2037:2041	Mutation rewiring degron network	0.3056
p.C4988F	SIDM01105	Melanoma	GDSC	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation rewiring degron network	0.25
p.C4988F	SK-MEL-3	skin	COSMIC	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation rewiring degron network	0.25
p.S4249N	SIDM01098	Neuroblastoma	GDSC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.0833
p.S4249N	UDSCC2	upper aerodigestive tract	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.0833
p.S4249N	SK-N-SH	autonomic ganglia	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.0833
p.G4261D	SIDM01098	Neuroblastoma	GDSC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.25
p.G4261D	SK-N-SH	autonomic ganglia	COSMIC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.25
p.G4261R	SIDM00720	Mesothelioma	GDSC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.25
p.H4687P	SIDM00808	Burkitt's Lymphoma	GDSC	PGSTT	DEG_SPOP_SBC_1	4677:4681	Mutation rewiring degron network	0.1667
p.Q1690R	SIDM00224	Mesothelioma	GDSC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation substituting flanking lysine	0.25
p.Q1690R	IST-MES1	pleura	COSMIC	PGSTT	DEG_SPOP_SBC_1	1679:1683	Mutation substituting flanking lysine	0.25
p.S823C	SIDM00303	Ovarian Carcinoma	GDSC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.3056
p.S823C	JHOS-4	ovary	COSMIC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.3056
p.E691Q	ACH-000211	Brain Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.1389
p.E691Q	Daoy	central nervous system	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.1389
p.T802K	ACH-000247	Gastric Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	ACH-000479	Brain Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	ACH-000843	Lung Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	ACH-000941	Endometrial/Uterine Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	ACH-000954	Endometrial/Uterine Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	ACH-001517	Endometrial/Uterine Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	ACH-001609	Brain Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	HEC-1	endometrium	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	KNS-81-FD	central nervous system	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	TALL-1	haematopoietic and lymphoid tissue	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	OCUM-1	stomach	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.T802K	HARA	lung	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7306
p.S626I	ACH-000364	Primary	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.7341
p.S626I	U-2-OS	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.7341
p.S753N	ACH-000581	Gastric Cancer	CCLE	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7069
p.S753N	ACH-000607	Rhabdoid	CCLE	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7069
p.S753N	KYM-1	soft tissue	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7069
p.S753N	NCI-SNU-16	stomach	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7069
p.S753N	SAT	upper aerodigestive tract	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation altering degron motif	0.7069
p.E4853D	ACH-000773	Lymphoma	CCLE	AESTT	DEG_SPOP_SBC_1	4852:4856	Mutation altering degron motif	0.5647
p.P1754R	ACH-000780	Lung Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation rewiring degron network	0.0833
p.P1754R	NCI-H1105	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	1763:1767	Mutation rewiring degron network	0.0833
p.T3700A	ACH-000823	Esophageal Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	3706:3710	Mutation rewiring degron network	0.1667
p.T3700A	KYSE-140	oesophagus	COSMIC	PGSTT	DEG_SPOP_SBC_1	3706:3710	Mutation rewiring degron network	0.1667
p.P3236H	ACH-000844	Lung Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation altering degron motif	0.7694
p.L4457M	ACH-000900	Lung Cancer	CCLE	VHSST	DEG_SPOP_SBC_1	4446:4450	Mutation rewiring degron network	0.1389
p.L4457M	ACH-000900	Lung Cancer	CCLE	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.25
p.R770S	ACH-000901	Lung Cancer	CCLE	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.3056
p.T684A	ACH-000930	Breast Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7139
p.T684A	HCC1569	breast	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7139
p.A765T	ACH-000941	Endometrial/Uterine Cancer	CCLE	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.7139
p.A765T	ACH-000954	Endometrial/Uterine Cancer	CCLE	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.7139
p.A765T	ACH-001526	Bone Cancer	CCLE	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.7139
p.A765T	YAPC	pancreas	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.7139
p.A765T	HuO9	bone	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation altering degron motif	0.7139
p.G1067S	ACH-000955	Colon/Colorectal Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	1066:1070	Mutation altering degron motif	0.5882
p.G1067S	SNU-407	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	1066:1070	Mutation altering degron motif	0.5882
p.P790H	ACH-000989	Colon/Colorectal Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.0556
p.P790H	SNU-175	large intestine	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.0556
p.T638I	ACH-000997	Colon/Colorectal Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.0556
p.T638I	HCT-15	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.0556
p.A622V	ACH-000999	Colon/Colorectal Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.2778
p.A622V	SNU-1040	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.2778
p.F679Y	ACH-000999	Colon/Colorectal Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.3056
p.G4404D	ACH-001188	Neuroblastoma	CCLE	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation altering degron motif	0.6087
p.G4404D	SK-N-SH	autonomic ganglia	COSMIC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation altering degron motif	0.6087
p.V798A	ACH-001277	Sarcoma	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2778
p.V798A	ACH-002021	Endometrial/Uterine Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2778
p.T4525R	ACH-001401	Adrenal Cancer	CCLE	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1111
p.T4525R	SW13	adrenal gland	COSMIC	ASSTT	DEG_SPOP_SBC_1	4513:4517	Mutation rewiring degron network	0.1111
p.S4977L	ACH-001550	Skin Cancer	CCLE	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation rewiring degron network	0.2222
p.S4977L	MCC13	skin	COSMIC	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation rewiring degron network	0.2222
p.M618V	ACH-001656	Leukemia	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1667
p.M618V	KMRC-20	kidney	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.1667
p.K629N	ACH-001669	Leukemia	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.3056
p.K629N	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.3056
p.P624R	ACH-001675	Head and Neck Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.7512
p.L467M	ACH-001685	Lymphoma	CCLE	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.3056
p.A4982D	ACH-001796	Liposarcoma	CCLE	PASTT	DEG_SPOP_SBC_1	4981:4985	Mutation altering degron motif	0.6682
p.H759Y	ACH-001970	Metastasis	CCLE	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2222
p.H759Y	ACH-001970	Metastasis	CCLE	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1667
p.T939M	ACH-001977	Primary	CCLE	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.P791T	ACH-002042	Thyroid Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.0833
p.T4928N	ACH-002143	Skin Cancer	CCLE	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation altering degron motif	0.7055
p.T4928N	IST-MEL1	skin	COSMIC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation altering degron motif	0.7055
p.E799K	ACH-002396	Bone Cancer	CCLE	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.3056
p.E799K	Sarc9371	bone	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.3056
p.T967N	ACH-002672	Pancreatic Cancer	CCLE	PGSTT	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.0833
p.S454A	HC-1	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.1111
p.Q1833R	IST-MES1	pleura	COSMIC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.0833
p.T3244A	EW-1	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2222
p.T3244A	Farage	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2222
p.T3244A	CADO-ES1	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2222
p.T3244A	NUGC-4	stomach	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2222
p.T3244A	HOS	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2222
p.L3119F	Raji	haematopoietic and lymphoid tissue	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.2222
p.L3119F	Raji	haematopoietic and lymphoid tissue	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.1667
p.L3119F	HCC1806	breast	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.2222
p.L3119F	HCC1806	breast	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.1667
p.T3124M	NCI-H2110	lung	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7423
p.T3124M	SiHa	cervix	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7423
p.T3124M	MOG-G-CCM	central nervous system	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7423
p.T3124M	TOV-21G	ovary	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7423
p.T3124M	Hep_3B2_1-7	NS	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7423
p.T3124M	NCI-H835	lung	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7423
p.P3283T	SNU-423	liver	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.0833
p.G681D	SNU-1040	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.6087
p.H3287L	CHP-126	autonomic ganglia	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.1944
p.P3115L	CTB-1	haematopoietic and lymphoid tissue	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1111
p.P3115L	CTB-1	haematopoietic and lymphoid tissue	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.P3115L	201T	lung	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1111
p.P3115L	201T	lung	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.P3115L	SCaBER	urinary tract	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1111
p.P3115L	SCaBER	urinary tract	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.P3115L	NCI-H2110	lung	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1111
p.P3115L	NCI-H2110	lung	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.P3115L	Hep_3B2_1-7	NS	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1111
p.P3115L	Hep_3B2_1-7	NS	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.T3387A	HOS	bone	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.T3387A	EW-1	bone	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.T3387A	NUGC-4	stomach	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.T3387A	CADO-ES1	bone	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.T3387A	Farage	haematopoietic and lymphoid tissue	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.R3113S	RKN	ovary	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.0556
p.R3294H	NCI-H1963	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.8244
p.R3294H	TE-441-T	soft tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.8244
p.L3292F	TE-441-T	soft tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6981
p.L3292F	NCI-N87	stomach	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6981
p.L3292F	HeLa	cervix	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6981
p.L3292F	MM1S	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6981
p.L3292F	EB2	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6981
p.L3292F	NCI-H1963	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6981
p.S3184P	647-V	urinary tract	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	HC-1	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	SHP-77	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	PANC-08-13	pancreas	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	LoVo	large intestine	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	OAW-42	ovary	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	Hs940-T	skin	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	NCI-H1623	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	CRO-AP2	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	MOG-G-UVW	central nervous system	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	HT-1197	urinary tract	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	COR-L23	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	H2869	pleura	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	NCI-H2227	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	JURL-MK1	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	Capan-2	pancreas	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	HCC2998	large intestine	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	WM278	skin	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	SCC-15	upper aerodigestive tract	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	SUP-B15	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	ROS-50	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	NCI-H446	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	L-1236	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	Hs-445	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	NCI-H226	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.S3184P	NCI-H358	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation altering degron motif	0.6752
p.H3371Q	DMS-79	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1667
p.P2743T	NCI-H1437	lung	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.1944
p.R4465H	EW-11	bone	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.3056
p.R4465H	HCC-15	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.3056
p.R4465H	COLO-680N	oesophagus	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.3056
p.R4465H	MDA-MB-361	breast	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.3056
p.R710H	NCI-H345	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation altering degron motif	0.8244
p.G3195A	HuH-7	liver	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.0556
p.G3195A	KYSE-510	oesophagus	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.0556
p.L3435F	EB2	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.L3435F	NCI-N87	stomach	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.L3435F	TE-441-T	soft tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.L3435F	NCI-H1963	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.L3435F	MM1S	haematopoietic and lymphoid tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.L3435F	HeLa	cervix	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.3056
p.E1227K	COLO-668	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.1944
p.F4472L	NCI-H1694	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.1111
p.S1121Y	LC4-1	haematopoietic and lymphoid tissue	COSMIC	PASST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.3056
p.T2031M	KARPAS-422	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	2037:2041	Mutation rewiring degron network	0.1667
p.T2725A	HN	upper aerodigestive tract	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.0833
p.G3128S	NCI-H510A	lung	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.6993
p.G3128S	NCI-H510A	lung	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation altering degron motif	0.6993
p.P3292L	KARPAS-1106P	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.P3292L	CAL-120	breast	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.P3292L	OVCAR-5	ovary	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.P3292L	SNB75	central nervous system	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.P3292L	DBTRG-05MG	central nervous system	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.P3292L	SW684	soft tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.P3292L	OAW-42	ovary	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.7582
p.T4464S	COLO-684	endometrium	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation altering degron motif	0.6005
p.P3292S	NCI-H1734	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation altering degron motif	0.6752
p.V924L	SW780	urinary tract	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.25
p.T3117S	NCI-H2452	pleura	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1667
p.T3117S	NCI-H2452	pleura	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.1111
p.R710G	Hs-578-T	breast	COSMIC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation altering degron motif	0.7568
p.P3376H	SK-MEL-2	skin	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.3056
p.P680H	TOV-21G	ovary	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7694
p.P680H	SNU-175	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7694
p.Q4323E	HCC-15	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.6744
p.Q4323E	COLO-680N	oesophagus	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.6744
p.S464F	KYSE-140	oesophagus	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation altering degron motif	0.7982
p.T777M	SJSA-1	bone	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1111
p.T721P	SKM-1	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.0833
p.T3118P	KURAMOCHI	ovary	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1944
p.T3118P	KURAMOCHI	ovary	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.1389
p.S3285P	SK-GT-4	oesophagus	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.1389
p.S3285P	LN-18	central nervous system	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.1389
p.E949G	CCF-STTG1	central nervous system	COSMIC	PGSTT	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1944
p.P624S	CHL-1	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.6752
p.G3384R	Mewo	skin	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.25
p.G4144A	Hep_3B2_1-7	NS	COSMIC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1111
p.G4144A	201T	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1111
p.G4144A	NCI-H2110	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1111
p.E3132G	LS-411N	large intestine	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.2222
p.E3132G	LS-411N	large intestine	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.25
p.A266V	SNU-C2B	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.A266V	SNU-283	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.A266V	NOMO-1	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.2778
p.Q4466E	HCC-15	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.2778
p.Q4466E	COLO-680N	oesophagus	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.2778
p.P456A	MDA-MB-468	breast	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.1667
p.P456A	CAL-72	bone	COSMIC	ASSTT	DEG_SPOP_SBC_1	462:466	Mutation rewiring degron network	0.1667
p.R3382C	HUTU-80	small intestine	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.3056
p.R3382C	RPMI-8226	haematopoietic and lymphoid tissue	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.3056
p.R3382C	NCI-H2081	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.3056
p.S804F	ATN-1	haematopoietic and lymphoid tissue	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.7982
p.T684N	EN	endometrium	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7055
p.R670Q	U-CH2	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.0556
p.T1739I	A427	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation altering degron motif	0.7078
p.T1739I	ESO51	oesophagus	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation altering degron motif	0.7078
p.T1739I	U-CH2	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation altering degron motif	0.7078
p.S2748N	SW684	soft tissue	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.0556
p.T1810S	KMRC-20	kidney	COSMIC	AGSTT	DEG_SPOP_SBC_1	1820:1824	Mutation rewiring degron network	0.0556
p.R3139Q	CP67-MEL	skin	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.R3139Q	SK-N-FI	autonomic ganglia	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.0556
p.L623S	HSC-39	stomach	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation rewiring degron network	0.3056
p.R4322H	EW-11	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.8244
p.R4322H	COLO-680N	oesophagus	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.8244
p.R4322H	MDA-MB-361	breast	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.8244
p.R4322H	HCC-15	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.8244
p.G4144C	NCI-H2023	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4152:4156	Mutation rewiring degron network	0.1111
p.S3441L	TE-441-T	soft tissue	COSMIC	ASSTT	DEG_SPOP_SBC_1	3430:3434	Mutation rewiring degron network	0.1389
p.S1747I	Ramos-2G6-4C10	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation rewiring degron network	0.1111
p.Q4242R	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.2778
p.S3127L	EB-3	haematopoietic and lymphoid tissue	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.6556
p.S3127L	EB-3	haematopoietic and lymphoid tissue	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation altering degron motif	0.7667
p.S3369L	H2373	pleura	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1111
p.S3369L	AU565	breast	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1111
p.S3369L	MN-60	haematopoietic and lymphoid tissue	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1111
p.S3369L	MPP-89	pleura	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1111
p.S3369L	KCL-22	haematopoietic and lymphoid tissue	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1111
p.A4317S	SK-MEL-1	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.2778
p.W4332L	NCI-H2126	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.0833
p.E3604K	RCM-1	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	3594:3598	Mutation rewiring degron network	0.1667
p.Q1131H	MLMA	haematopoietic and lymphoid tissue	COSMIC	PASST	DEG_SPOP_SBC_1	1122:1126	Mutation rewiring degron network	0.1944
p.Q4915E	COLO-320-HSR	large intestine	COSMIC	PASTT	DEG_SPOP_SBC_1	4925:4929	Mutation rewiring degron network	0.0556
p.A741T	SNU-175	large intestine	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.0556
p.F2746L	NCI-H1563	lung	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.1111
p.P3298R	HT-144	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.2778
p.G4467E	Mewo	skin	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.25
p.S3194R	RERF-LC-Sq1	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.0833
p.P1431H	HSC-2	upper aerodigestive tract	COSMIC	PTTPSLS	DEG_SCF_FBW7_1	1431:1437	Mutation altering degron motif	0.7694
p.S3136Y	KYSE-450	oesophagus	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation rewiring degron network	0.1111
p.S3136Y	KYSE-450	oesophagus	COSMIC	PASST	DEG_SPOP_SBC_1	3125:3129	Mutation rewiring degron network	0.1389
p.A713E	EBC-1	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	708:712	Mutation rewiring degron network	0.3056
p.R3282Q	CP67-MEL	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.0556
p.R3282Q	SK-N-FI	autonomic ganglia	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.0556
p.V1303I	RCC-ER	kidney	COSMIC	VYSSS	DEG_SPOP_SBC_1	1303:1307	Mutation altering degron motif	0.7076
p.V1303I	PC-3_[JPC-3]	lung	COSMIC	VYSSS	DEG_SPOP_SBC_1	1303:1307	Mutation altering degron motif	0.7076
p.G1238S	SK-N-FI	autonomic ganglia	COSMIC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.2778
p.V1743L	HCC-44	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation rewiring degron network	0.2222
p.V1743L	NCI-H522	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation rewiring degron network	0.2222
p.A4604T	NCI-H2029	lung	COSMIC	APSTT	DEG_SPOP_SBC_1	4594:4598	Mutation rewiring degron network	0.1667
p.S4410P	NCI-H1770	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.25
p.G3368A	NCI-H292	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.0833
p.S3298L	TE-441-T	soft tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.2778
p.P808A	CCF-STTG1	central nervous system	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2222
p.P808A	CCF-STTG1	central nervous system	COSMIC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.0556
p.G625S	SHP-77	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	624:628	Mutation altering degron motif	0.5882
p.G4461S	KYSE-510	oesophagus	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation altering degron motif	0.5882
p.T4313M	SW780	urinary tract	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation rewiring degron network	0.1667
p.T1748I	HuH-7	liver	COSMIC	PGSTT	DEG_SPOP_SBC_1	1735:1739	Mutation rewiring degron network	0.0833
p.T3072I	SK-MEL-5	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	3069:3073	Mutation altering degron motif	0.7078
p.P926T	NCI-H1299	lung	COSMIC	ARSTT	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.3056
p.A3234D	H3255	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2778
p.P2743L	SK-N-DZ	autonomic ganglia	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.1944
p.T3380A	NCI-H2172	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation altering degron motif	0.7139
p.T776R	ATN-1	haematopoietic and lymphoid tissue	COSMIC	AGSTT	DEG_SPOP_SBC_1	765:769	Mutation rewiring degron network	0.1389
p.G4215A	IGR-37	skin	COSMIC	LTPASS	DEG_SCF_FBW7_1	4206:4211	Mutation rewiring degron network	0.2222
p.G4215A	IGR-37	skin	COSMIC	PASST	DEG_SPOP_SBC_1	4208:4212	Mutation rewiring degron network	0.25
p.S966C	JHOS-4	ovary	COSMIC	PGSTT	DEG_SPOP_SBC_1	954:958	Mutation rewiring degron network	0.1111
p.P3283S	MM1S	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.0833
p.L4269V	A673	bone	COSMIC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation rewiring degron network	0.3056
p.P3706S	HCC1806	breast	COSMIC	PGSTT	DEG_SPOP_SBC_1	3706:3710	Mutation altering degron motif	0.6752
p.D3701Y	WM35	skin	COSMIC	PGSTT	DEG_SPOP_SBC_1	3706:3710	Mutation rewiring degron network	0.1944
p.S4267P	NCI-H1770	lung	COSMIC	ASSTT	DEG_SPOP_SBC_1	4264:4268	Mutation altering degron motif	0.6752
p.T1246N	EB-3	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	1232:1236	Mutation rewiring degron network	0.0556
p.S3375P	MN-60	haematopoietic and lymphoid tissue	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation blocking phosphorylation signal	0.7222
p.P4394Q	SNU-1040	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	4403:4407	Mutation rewiring degron network	0.0833
p.P680R	SUP-B15	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation altering degron motif	0.7512
p.S3232P	MN-60	haematopoietic and lymphoid tissue	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.2222
p.H2747Y	SW684	soft tissue	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation rewiring degron network	0.0833
p.P3298S	SW1271	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3292:3296	Mutation rewiring degron network	0.2778
p.E4243K	NCI-H1299	lung	COSMIC	PPSTT	DEG_SPOP_SBC_1	4236:4240	Mutation rewiring degron network	0.25
p.M749I	SBC-1	lung	COSMIC	VHSST	DEG_SPOP_SBC_1	751:755	Mutation rewiring degron network	0.2778
p.P808Q	NCI-H2342	lung	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation rewiring degron network	0.2222
p.P808Q	NCI-H2342	lung	COSMIC	ARSTT	DEG_SPOP_SBC_1	818:822	Mutation rewiring degron network	0.0556
p.A4460S	SK-MEL-1	skin	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation altering degron motif	0.7588
p.T2745A	NCI-H1437	lung	COSMIC	PASST	DEG_SPOP_SBC_1	2734:2738	Mutation substituting flanking lysine	0.25
p.F679L	U-CH2	bone	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.3056
p.A3377D	H3255	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	3377:3381	Mutation altering degron motif	0.7793
p.H3228Q	DMS-79	lung	COSMIC	PGSTT	DEG_SPOP_SBC_1	3236:3240	Mutation rewiring degron network	0.1111
p.A3074T	DU-145	prostate	COSMIC	PGSTT	DEG_SPOP_SBC_1	3069:3073	Mutation rewiring degron network	0.3056
p.P693L	NCI-H630	large intestine	COSMIC	PGSTT	DEG_SPOP_SBC_1	680:684	Mutation rewiring degron network	0.0833
p.T4321S	COLO-684	endometrium	COSMIC	PGSTT	DEG_SPOP_SBC_1	4319:4323	Mutation altering degron motif	0.7116
p.S3176P	SW48	large intestine	COSMIC	ASSTT	DEG_SPOP_SBC_1	3181:3185	Mutation rewiring degron network	0.1944
p.S4474R	NCI-H1573	lung	COSMIC	AGSTT	DEG_SPOP_SBC_1	4460:4464	Mutation rewiring degron network	0.0556
p.S3123R	SCaBER	urinary tract	COSMIC	LTPASS	DEG_SCF_FBW7_1	3123:3128	Mutation altering degron motif	0.7427
p.S801F	REH	haematopoietic and lymphoid tissue	COSMIC	PSTTS	DEG_SPOP_SBC_1	800:804	Mutation altering degron motif	0.6871
p.S267G	NB69	autonomic ganglia	COSMIC	PGSTT	DEG_SPOP_SBC_1	268:272	Mutation rewiring degron network	0.3056

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC12

UniProt ID: Q9UKN1

Entrez ID: 10071

Protein name: Mucin-12 (MUC-12) (Mucin-11) (MUC-11)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC12 in