DegronMD

Uniprot ID: Q9BWK5

Source protein: Cell cycle regulator of non-homologous end joining

Source gene: CYREN

Class: DEG_SPOP_SBC_1

Location: 100:104

E3 ligase: SPOP

DEGRON score: 0.9513

ASA_SCORE: 96.88

COIL: 0.958

CONS_SCORE: 0.3941

DSS_SCORE: 0.7703

HELIX: 0.0238

FCONS_SCORE: 0.6963

RIG_SCORE: 0.4801

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9BWK5	Cell cycle regulator of non-homologous end joining	DEG_SPOP_SBC_1	100:104	PHTSS	SPOP	0.9513	More...
O95402	Mediator of RNA polymerase II transcription subunit 26	DEG_SPOP_SBC_1	228:232	PHTSS	SPOP	0.9917	More...
P56645	Period circadian protein homolog 3	DEG_SPOP_SBC_1	778:782	PHTSS	SPOP	0.9879	More...
Q8IXK0	Polyhomeotic-like protein 2	DEG_SPOP_SBC_1	8:12	PHTSS	SPOP	0.9118	More...
Q9BQS2	Synaptotagmin-15	DEG_SPOP_SBC_1	111:115	PHTSS	SPOP	0.9607	More...

Showing 1 to 5 of 5 entries

DegronMD: protein-targeted degradation, mutation and drug response to degrons