DegronMD

Uniprot ID: Q9H195

Source protein: Mucin-3B

Source gene: MUC3B

Class: DEG_SPOP_SBC_1

Location: 259:263

E3 ligase: SPOP

DEGRON score: 0.9811

ASA_SCORE: 97.92

COIL: 0.9386

CONS_SCORE: 0.5019

DSS_SCORE: 0.4318

HELIX: 0.014

FCONS_SCORE: 1.1284

RIG_SCORE: 0.7592

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5JSP0	FYVE, RhoGEF and PH domain-containing protein 3	DEG_SPOP_SBC_1	498:502	PITST	SPOP	0.9839	More...
Q9H195	Mucin-3B	DEG_SPOP_SBC_1	259:263	PITST	SPOP	0.9811	More...
P98088	Mucin-5AC	DEG_SPOP_SBC_1	3787:3791	PITST	SPOP	0.5313	More...
Q9BVL2	Nucleoporin p58/p45	DEG_SPOP_SBC_1	125:129	PITST	SPOP	0.9804	More...
P13611	Versican core protein	DEG_SPOP_SBC_1	908:912	PITST	SPOP	0.9967	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons