DegronMD

Uniprot ID: Q5VZ18

Source protein: SH2 domain-containing adapter protein E

Source gene: SHE

Class: DEG_SCF_FBW7_1

Location: 5:10

E3 ligase: FBXW7

DEGRON score: 0.9762

ASA_SCORE: 66.3833

COIL: 0.8993

CONS_SCORE: 0.4189

DSS_SCORE: 0.4708

HELIX: 0.049

FCONS_SCORE: 1.0273

RIG_SCORE: 0.707

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O75533	Splicing factor 3B subunit 1	DEG_SCF_FBW7_1	327:332	PTPGAS	FBXW7	0.9834	More...
Q86TM6	E3 ubiquitin-protein ligase synoviolin	DEG_SCF_FBW7_1	567:572	PTPGAS	FBXW7	0.9928	More...
Q8NAG6	Ankyrin repeat and LEM domain-containing protein 1	DEG_SCF_FBW7_1	310:315	PTPGAS	FBXW7	0.9884	More...
Q5VZ18	SH2 domain-containing adapter protein E	DEG_SCF_FBW7_1	5:10	PTPGAS	FBXW7	0.9762	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons