Degron: PTTTPITT
Mucin-2
MUC2
1942:1949
FBXW7
0.9972
101.75
0.9503
0.3326
0.6965
0.0115
1.1054
0.7134
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.T1939K | TCGA-85-8352 | LUSC | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.25 |
p.T1948M | TCGA-BR-8591 | STAD | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.6312 |
p.P1951S | TCGA-D9-A149 | SKCM | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.2778 |
p.T1939M | TCGA-DD-AACY | LIHC | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.25 |
p.T1939M | TCGA-UF-A7JH | HNSC | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.25 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of PTTTPITT