DegronMD - Q02817(MUC2)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R2808W	TCGA-05-4390	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.8634
p.R2808W	DO23562	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.8634
p.F2243L	TCGA-05-4398	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2241:2248	Mutation altering degron motif	0.6981
p.D2515N	TCGA-06-0184	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation rewiring degron network	0.25
p.D2515N	TCGA-06-0184	GBM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation rewiring degron network	0.2778
p.D2515N	TCGA-06-0184	GBM	TCGA	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.D2515N	DO12496	GBM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation rewiring degron network	0.25
p.D2515N	DO12496	GBM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation rewiring degron network	0.2778
p.D2515N	DO12496	GBM	ICGC	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.D2515N	ACH-000996	Endometrial/Uterine Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation rewiring degron network	0.25
p.D2515N	ACH-000996	Endometrial/Uterine Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation rewiring degron network	0.2778
p.D2515N	ACH-000996	Endometrial/Uterine Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1667
p.V2153M	TCGA-06-0650	GBM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2149:2156	Mutation altering degron motif	0.7208
p.V2153M	TCGA-06-0650	GBM	TCGA	PITTT	DEG_SPOP_SBC_1	2153:2157	Mutation altering degron motif	0.7208
p.V2153M	ACH-000963	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2149:2156	Mutation altering degron motif	0.7208
p.V2153M	ACH-000963	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2153:2157	Mutation altering degron motif	0.7208
p.S1907F	TCGA-06-5416	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.7982
p.S1907F	DO10880	GBM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.7982
p.R1964M	TCGA-06-5416	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1953:1960	Mutation rewiring degron network	0.2222
p.R1964M	TCGA-06-5416	GBM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation rewiring degron network	0.3056
p.R1964M	TCGA-06-5416	GBM	TCGA	PITTT	DEG_SPOP_SBC_1	1969:1973	Mutation rewiring degron network	0.1944
p.E2182K	TCGA-06-5416	GBM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation rewiring degron network	0.25
p.E2182K	TCGA-06-5416	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2183:2190	Mutation rewiring degron network	0.3056
p.E2182K	TCGA-06-5416	GBM	TCGA	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation rewiring degron network	0.2778
p.A2443G	TCGA-06-5416	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2436:2443	Mutation altering degron motif	0.754
p.A2443G	DO10880	GBM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2436:2443	Mutation altering degron motif	0.754
p.C2658Y	TCGA-06-5416	GBM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.7087
p.C2658Y	DO10880	GBM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.7087
p.V1294G	TCGA-12-0822	GBM	TCGA	VLSTT	DEG_SPOP_SBC_1	1294:1298	Mutation altering degron motif	0.7532
p.V1294G	DO11064	GBM	ICGC	VLSTT	DEG_SPOP_SBC_1	1294:1298	Mutation altering degron motif	0.7532
p.C2518S	TCGA-17-Z023	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation altering degron motif	0.7541
p.E2049K	TCGA-19-5956	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2045:2052	Mutation altering degron motif	0.7022
p.S2303R	TCGA-19-5956	GBM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation altering degron motif	0.7427
p.S2303R	DO13863	GBM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation altering degron motif	0.7427
p.V2236F	TCGA-21-5787	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2229:2236	Mutation altering degron motif	0.7068
p.E2148K	TCGA-25-2398	OV	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2137:2144	Mutation rewiring degron network	0.2222
p.E2148K	TCGA-25-2398	OV	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.3056
p.E2148K	TCGA-25-2398	OV	TCGA	PITTT	DEG_SPOP_SBC_1	2153:2157	Mutation rewiring degron network	0.1944
p.R2808Q	TCGA-2W-A8YY	CESC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7329
p.R2808Q	TCGA-L5-A8NG	ESCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7329
p.R2808Q	DO223732	CESC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7329
p.S2804F	TCGA-34-2600	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7982
p.S2804F	DO27081	LUSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7982
p.M1885V	TCGA-34-8454	LUSC	TCGA	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1111
p.M1885V	TCGA-34-8454	LUSC	TCGA	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.0556
p.V2548M	TCGA-46-6025	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation altering degron motif	0.7208
p.V2548M	DO26644	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation altering degron motif	0.7208
p.R2809C	TCGA-4Z-AA7M	BLCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.8301
p.R2809C	DO218976	BLCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.8301
p.V2674F	TCGA-50-5045	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation rewiring degron network	0.3056
p.V2674F	TCGA-50-5045	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2678:2685	Mutation rewiring degron network	0.2222
p.V2674F	TCGA-50-5045	LUAD	TCGA	PITTT	DEG_SPOP_SBC_1	2682:2686	Mutation rewiring degron network	0.1111
p.V2674F	DO23723	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation rewiring degron network	0.3056
p.V2674F	DO23723	LUAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2678:2685	Mutation rewiring degron network	0.2222
p.V2674F	DO23723	LUAD	ICGC	PITTT	DEG_SPOP_SBC_1	2682:2686	Mutation rewiring degron network	0.1111
p.G2276V	TCGA-55-6979	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7532
p.G2276V	TCGA-DA-A1I1	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7532
p.G2276V	DO24110	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7532
p.G2276V	DO37966	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7532
p.A2601S	TCGA-55-8514	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2597:2604	Mutation altering degron motif	0.7588
p.A2601S	DO23616	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2597:2604	Mutation altering degron motif	0.7588
p.F2694L	TCGA-55-A4DF	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation altering degron motif	0.6981
p.F2694L	DO45318	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation altering degron motif	0.6981
p.T2803N	TCGA-56-8307	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2793:2800	Mutation rewiring degron network	0.25
p.T2803N	TCGA-56-8307	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation rewiring degron network	0.3056
p.T2803N	TCGA-56-8307	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	2797:2801	Mutation rewiring degron network	0.2778
p.T2803N	DO219139	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2793:2800	Mutation rewiring degron network	0.25
p.T2803N	DO219139	LUSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation rewiring degron network	0.3056
p.T2803N	DO219139	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2797:2801	Mutation rewiring degron network	0.2778
p.S1832G	TCGA-56-8628	LUSC	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.2778
p.S1832G	DO45433	LUSC	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.2778
p.Y1966F	TCGA-63-A5MR	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation altering degron motif	0.7528
p.G2457E	TCGA-66-2754	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2448:2455	Mutation rewiring degron network	0.2778
p.G2457E	TCGA-66-2754	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.2778
p.G2457E	TCGA-66-2754	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	2452:2456	Mutation rewiring degron network	0.3056
p.G2457E	DO27612	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2448:2455	Mutation rewiring degron network	0.2778
p.G2457E	DO27612	LUSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.2778
p.G2457E	DO27612	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2452:2456	Mutation rewiring degron network	0.3056
p.P2415H	TCGA-69-7979	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2413:2420	Mutation altering degron motif	0.6583
p.P2415H	DO23874	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2413:2420	Mutation altering degron motif	0.6583
p.A2354P	TCGA-75-5146	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.25
p.A2354P	TCGA-75-5146	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation rewiring degron network	0.2778
p.A2354P	TCGA-75-5146	LUAD	TCGA	PITTT	DEG_SPOP_SBC_1	2360:2364	Mutation rewiring degron network	0.1667
p.A2354P	DO25228	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.25
p.A2354P	DO25228	LUAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation rewiring degron network	0.2778
p.A2354P	DO25228	LUAD	ICGC	PITTT	DEG_SPOP_SBC_1	2360:2364	Mutation rewiring degron network	0.1667
p.L2273V	TCGA-77-7141	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation rewiring degron network	0.2778
p.L2273V	TCGA-77-7141	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation rewiring degron network	0.2778
p.L2273V	TCGA-77-7141	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.3056
p.L2273V	DO26450	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation rewiring degron network	0.2778
p.L2273V	DO26450	LUSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation rewiring degron network	0.2778
p.L2273V	DO26450	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.3056
p.A2750V	TCGA-77-8130	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.6936
p.A2750V	DO26566	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.6936
p.K2474R	TCGA-77-8143	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation altering degron motif	0.7237
p.K2474R	DO27247	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation altering degron motif	0.7237
p.T1905I	TCGA-78-7220	LUAD	TCGA	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1389
p.T1905I	TCGA-78-7220	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation rewiring degron network	0.2778
p.T1905I	TCGA-78-7220	LUAD	TCGA	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1667
p.T1905I	TCGA-78-7220	LUAD	TCGA	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.3056
p.T1905I	DO24409	LUAD	ICGC	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1389
p.T1905I	DO24409	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation rewiring degron network	0.2778
p.T1905I	DO24409	LUAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1667
p.T1905I	DO24409	LUAD	ICGC	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.3056
p.T1905I	ACH-000947	Ovarian Cancer	CCLE	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1389
p.T1905I	ACH-000947	Ovarian Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation rewiring degron network	0.2778
p.T1905I	ACH-000947	Ovarian Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1667
p.T1905I	ACH-000947	Ovarian Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.3056
p.A2752S	TCGA-80-5611	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7588
p.A2752S	TCGA-80-5611	LUAD	TCGA	PITTT	DEG_SPOP_SBC_1	2751:2755	Mutation altering degron motif	0.7588
p.A2752S	DO23822	LUAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7588
p.A2752S	DO23822	LUAD	ICGC	PITTT	DEG_SPOP_SBC_1	2751:2755	Mutation altering degron motif	0.7588
p.L2209M	TCGA-85-6561	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2206:2213	Mutation altering degron motif	0.711
p.T1939K	TCGA-85-8352	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation rewiring degron network	0.2778
p.T1939K	TCGA-85-8352	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1942:1949	Mutation rewiring degron network	0.25
p.T1939K	TCGA-85-8352	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	1946:1950	Mutation rewiring degron network	0.1389
p.P2309T	TCGA-86-8281	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation rewiring degron network	0.2222
p.P2309T	TCGA-86-8281	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation rewiring degron network	0.3056
p.P2309T	TCGA-86-8281	LUAD	TCGA	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation rewiring degron network	0.1944
p.P2309T	DO26318	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation rewiring degron network	0.2222
p.P2309T	DO26318	LUAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation rewiring degron network	0.3056
p.P2309T	DO26318	LUAD	ICGC	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation rewiring degron network	0.1944
p.G2562E	TCGA-90-A4ED	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.2222
p.G2562E	TCGA-90-A4ED	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation rewiring degron network	0.3056
p.G2562E	TCGA-90-A4ED	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation rewiring degron network	0.1944
p.G2562E	DO45482	LUSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.2222
p.G2562E	DO45482	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation rewiring degron network	0.3056
p.G2562E	DO45482	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation rewiring degron network	0.1944
p.T1818A	TCGA-96-A4JK	LUSC	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1667
p.T1818A	DO45442	LUSC	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1667
p.G2044D	TCGA-96-A4JK	LUSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation rewiring degron network	0.25
p.G2044D	TCGA-96-A4JK	LUSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2045:2052	Mutation rewiring degron network	0.3056
p.G2044D	TCGA-96-A4JK	LUSC	TCGA	PITTT	DEG_SPOP_SBC_1	2038:2042	Mutation rewiring degron network	0.2778
p.G2044D	TCGA-ND-A4WC	UCS	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation rewiring degron network	0.25
p.G2044D	TCGA-ND-A4WC	UCS	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2045:2052	Mutation rewiring degron network	0.3056
p.G2044D	TCGA-ND-A4WC	UCS	TCGA	PITTT	DEG_SPOP_SBC_1	2038:2042	Mutation rewiring degron network	0.2778
p.S2747L	TCGA-A2-A0YD	BRCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7667
p.S2747L	DO5710	BRCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7667
p.T1925M	TCGA-A4-A57E	KIRP	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation altering degron motif	0.6312
p.T1925M	TCGA-A4-A57E	KIRP	TCGA	PITTT	DEG_SPOP_SBC_1	1923:1927	Mutation altering degron motif	0.7423
p.E2470G	TCGA-A5-A0G1	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.2222
p.E2470G	TCGA-A5-A0G1	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.3056
p.E2470G	TCGA-A5-A0G1	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1944
p.E2470G	DO42472	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.2222
p.E2470G	DO42472	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.3056
p.E2470G	DO42472	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1944
p.E2721D	TCGA-A5-A0G1	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.2778
p.E2721D	TCGA-A5-A0G1	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation rewiring degron network	0.25
p.E2721D	TCGA-A5-A0G1	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation rewiring degron network	0.1389
p.E2721D	DO42472	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.2778
p.E2721D	DO42472	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation rewiring degron network	0.25
p.E2721D	DO42472	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation rewiring degron network	0.1389
p.S1832N	TCGA-A5-A0G2	UCEC	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.2778
p.S1832N	DO41235	UCEC	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.2778
p.A1889T	TCGA-A5-A0VP	UCEC	TCGA	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.2222
p.A1889T	TCGA-A5-A0VP	UCEC	TCGA	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1667
p.A1889T	DO42600	UCEC	ICGC	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.2222
p.A1889T	DO42600	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1667
p.V2234I	TCGA-A5-A0VP	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2229:2236	Mutation altering degron motif	0.7076
p.H2499Y	TCGA-A5-A2K2	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation altering degron motif	0.7229
p.H2499Y	TCGA-A5-A2K2	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation altering degron motif	0.7229
p.H2499Y	DO40859	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation altering degron motif	0.7229
p.H2499Y	DO40859	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation altering degron motif	0.7229
p.T2120M	TCGA-A6-3809	COAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation altering degron motif	0.7423
p.T2120M	TCGA-EB-A4IS	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation altering degron motif	0.7423
p.T2120M	ACH-001097	Lymphoma	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation altering degron motif	0.7423
p.V2497I	TCGA-A7-A13F	BRCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation altering degron motif	0.7076
p.V2497I	DO4098	BRCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation altering degron motif	0.7076
p.E2542K	TCGA-AA-3510	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	TCGA-AJ-A3EL	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	TCGA-AP-A0LM	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	TCGA-AZ-6601	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	TCGA-DU-8168	LGG	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	DO8119	COAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	DO7783	COAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	DO22367	LGG	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	DO43306	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.E2542K	DO41542	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7022
p.T1837P	TCGA-AA-3715	COAD	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.T1837P	DO8018	COAD	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.P2248T	TCGA-AA-A01R	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2241:2248	Mutation altering degron motif	0.7031
p.P2248T	TCGA-AA-A01R	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2245:2249	Mutation altering degron motif	0.7031
p.D2161H	TCGA-AC-A23C	BRCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation altering degron motif	0.7688
p.L2065M	TCGA-AD-A5EJ	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2061:2065	Mutation altering degron motif	0.711
p.A2376T	TCGA-AJ-A3EL	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation rewiring degron network	0.2778
p.A2376T	TCGA-AJ-A3EL	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.25
p.A2376T	TCGA-AJ-A3EL	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.1389
p.A2376T	DO229242	THCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation rewiring degron network	0.2778
p.A2376T	DO229242	THCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.25
p.A2376T	DO229242	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.1389
p.A2376T	DO41542	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation rewiring degron network	0.2778
p.A2376T	DO41542	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.25
p.A2376T	DO41542	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.1389
p.S2280F	TCGA-AK-3451	KIRC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7982
p.S2280F	DO18899	KIRC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7982
p.G2815E	TCGA-AL-3473	KIRP	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation rewiring degron network	0.2222
p.G2815E	TCGA-AL-3473	KIRP	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2816:2823	Mutation rewiring degron network	0.3056
p.G2815E	TCGA-AL-3473	KIRP	TCGA	PITTT	DEG_SPOP_SBC_1	2820:2824	Mutation rewiring degron network	0.1944
p.G2815E	DO20905	KIRP	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation rewiring degron network	0.2222
p.G2815E	DO20905	KIRP	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2816:2823	Mutation rewiring degron network	0.3056
p.G2815E	DO20905	KIRP	ICGC	PITTT	DEG_SPOP_SBC_1	2820:2824	Mutation rewiring degron network	0.1944
p.G2815E	ACH-002177	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation rewiring degron network	0.2222
p.G2815E	ACH-002177	Lung Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2816:2823	Mutation rewiring degron network	0.3056
p.G2815E	ACH-002177	Lung Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2820:2824	Mutation rewiring degron network	0.1944
p.D2169N	TCGA-AP-A0LM	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation rewiring degron network	0.2778
p.D2169N	TCGA-AP-A0LM	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation rewiring degron network	0.25
p.D2169N	TCGA-AP-A0LM	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation rewiring degron network	0.1389
p.R2308H	TCGA-AP-A0LM	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation rewiring degron network	0.25
p.R2308H	TCGA-AP-A0LM	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation rewiring degron network	0.2778
p.R2308H	TCGA-AP-A0LM	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation rewiring degron network	0.1667
p.R2308H	DO43306	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation rewiring degron network	0.25
p.R2308H	DO43306	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation rewiring degron network	0.2778
p.R2308H	DO43306	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation rewiring degron network	0.1667
p.R2768H	TCGA-AP-A0LM	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2758:2765	Mutation rewiring degron network	0.25
p.R2768H	TCGA-AP-A0LM	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2770:2777	Mutation rewiring degron network	0.2778
p.R2768H	TCGA-AP-A0LM	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2774:2778	Mutation rewiring degron network	0.1667
p.R2768H	DO43306	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2758:2765	Mutation rewiring degron network	0.25
p.R2768H	DO43306	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2770:2777	Mutation rewiring degron network	0.2778
p.R2768H	DO43306	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2774:2778	Mutation rewiring degron network	0.1667
p.G2121D	TCGA-AP-A1DK	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation altering degron motif	0.7198
p.G1646D	TCGA-AP-A1DV	UCEC	TCGA	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7198
p.G1646D	TCGA-BS-A0TC	UCEC	TCGA	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7198
p.G1646D	DO43186	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7198
p.G1646D	DO42400	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7198
p.D2324Y	TCGA-AR-A24Q	BRCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2321:2328	Mutation altering degron motif	0.7325
p.D2324Y	DO3524	BRCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2321:2328	Mutation altering degron motif	0.7325
p.V1999I	TCGA-AX-A1CE	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1999:2006	Mutation altering degron motif	0.5965
p.G2132R	TCGA-AX-A1CE	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation altering degron motif	0.7568
p.G2132R	TCGA-AX-A1CE	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2130:2134	Mutation altering degron motif	0.7568
p.V2179M	TCGA-AX-A1CE	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.7208
p.V2179M	TCGA-AX-A1CE	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation altering degron motif	0.7208
p.V2179M	TCGA-VQ-A8PP	STAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.7208
p.V2179M	TCGA-VQ-A8PP	STAD	TCGA	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation altering degron motif	0.7208
p.R2180H	TCGA-AX-A1CE	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation altering degron motif	0.8244
p.E2470K	TCGA-AX-A1CE	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.2222
p.E2470K	TCGA-AX-A1CE	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.3056
p.E2470K	TCGA-AX-A1CE	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1944
p.E2470K	DO42280	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.2222
p.E2470K	DO42280	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.3056
p.E2470K	DO42280	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1944
p.A2601T	TCGA-AX-A2HA	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2597:2604	Mutation altering degron motif	0.7139
p.A2601T	DO42504	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2597:2604	Mutation altering degron motif	0.7139
p.C2624R	TCGA-AX-A2HJ	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation altering degron motif	0.8301
p.C2624R	DO42105	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation altering degron motif	0.8301
p.G1715D	TCGA-AX-A3G9	UCEC	TCGA	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation altering degron motif	0.7198
p.P2274R	TCGA-B4-5832	KIRC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation rewiring degron network	0.25
p.P2274R	TCGA-B4-5832	KIRC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation rewiring degron network	0.3056
p.P2274R	TCGA-B4-5832	KIRC	TCGA	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.2778
p.P2274R	DO17236	KIRC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation rewiring degron network	0.25
p.P2274R	DO17236	KIRC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation rewiring degron network	0.3056
p.P2274R	DO17236	KIRC	ICGC	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.2778
p.S1292N	TCGA-B5-A0JV	UCEC	TCGA	PTSST	DEG_SPOP_SBC_1	1289:1293	Mutation altering degron motif	0.7069
p.S1292N	DO43979	UCEC	ICGC	PTSST	DEG_SPOP_SBC_1	1289:1293	Mutation altering degron motif	0.7069
p.L1971R	TCGA-B5-A0JY	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation altering degron motif	0.8428
p.L1971R	TCGA-B5-A0JY	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	1969:1973	Mutation altering degron motif	0.8428
p.K2655N	TCGA-B5-A1MR	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.6918
p.K2655N	DO41758	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.6918
p.K2729N	TCGA-B5-A1MR	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation altering degron motif	0.6918
p.K2729N	TCGA-B5-A1MR	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation altering degron motif	0.6918
p.K2729N	DO41758	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation altering degron motif	0.6918
p.K2729N	DO41758	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation altering degron motif	0.6918
p.K2170N	TCGA-BF-A1PU	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation rewiring degron network	0.25
p.K2170N	TCGA-BF-A1PU	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation rewiring degron network	0.2778
p.K2170N	TCGA-BF-A1PU	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation rewiring degron network	0.1667
p.S1969F	TCGA-BF-A5EO	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation altering degron motif	0.7982
p.S1969F	TCGA-BF-A5EO	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	1969:1973	Mutation altering degron motif	0.7982
p.P1667A	TCGA-BH-A208	BRCA	TCGA	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.3056
p.P1667A	TCGA-BH-A208	BRCA	TCGA	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.0833
p.V2356M	TCGA-BK-A6W3	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation altering degron motif	0.7208
p.V2356M	DO50076	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation altering degron motif	0.7208
p.T2631M	TCGA-BK-A6W3	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	TCGA-BK-A6W3	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	TCGA-BK-A6W3	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.T2631M	TCGA-EO-A3B0	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	TCGA-EO-A3B0	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	TCGA-EO-A3B0	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.T2631M	TCGA-L5-A4OI	ESCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	TCGA-L5-A4OI	ESCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	TCGA-L5-A4OI	ESCA	TCGA	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.T2631M	TCGA-UY-A78M	BLCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	TCGA-UY-A78M	BLCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	TCGA-UY-A78M	BLCA	TCGA	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.T2631M	DO219033	BLCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	DO219033	BLCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	DO219033	BLCA	ICGC	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.T2631M	DO219773	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	DO219773	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	DO219773	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.T2631M	DO50076	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation rewiring degron network	0.2222
p.T2631M	DO50076	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.3056
p.T2631M	DO50076	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.1944
p.P1723L	TCGA-BR-4187	STAD	TCGA	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1944
p.P1723L	TCGA-BR-4187	STAD	TCGA	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2222
p.R2175H	TCGA-BR-4361	STAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.8244
p.R2175H	TCGA-EO-A22U	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.8244
p.R2175H	ACH-001127	Leukemia	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.8244
p.T1948M	TCGA-BR-8591	STAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1942:1949	Mutation altering degron motif	0.6312
p.T1948M	TCGA-BR-8591	STAD	TCGA	PITTT	DEG_SPOP_SBC_1	1946:1950	Mutation altering degron motif	0.7423
p.P2167T	TCGA-BR-A4QL	STAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation altering degron motif	0.7031
p.T1605N	TCGA-BS-A0UA	UCEC	TCGA	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1111
p.T1605N	DO42552	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1111
p.R2251W	TCGA-CK-5916	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2241:2248	Mutation rewiring degron network	0.25
p.R2251W	TCGA-CK-5916	COAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2252:2259	Mutation rewiring degron network	0.3056
p.R2251W	TCGA-CK-5916	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2245:2249	Mutation rewiring degron network	0.2778
p.S2672L	TCGA-CN-6020	HNSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation altering degron motif	0.7667
p.S2672L	DO14550	HNSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation altering degron motif	0.7667
p.K2655R	TCGA-CQ-7072	HNSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.7237
p.K2655R	DO52052	HNSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.7237
p.M2193I	TCGA-CR-5248	HNSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2183:2190	Mutation rewiring degron network	0.25
p.M2193I	TCGA-CR-5248	HNSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2195:2202	Mutation rewiring degron network	0.2778
p.M2193I	TCGA-CR-5248	HNSC	TCGA	PITTT	DEG_SPOP_SBC_1	2199:2203	Mutation rewiring degron network	0.1667
p.S1501I	TCGA-D1-A103	UCEC	TCGA	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1667
p.S1501I	TCGA-D1-A103	UCEC	TCGA	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.0556
p.E2616K	TCGA-D1-A167	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	TCGA-D1-A167	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	TCGA-D1-A16Y	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	TCGA-D1-A16Y	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	TCGA-EO-A3AV	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	TCGA-EO-A3AV	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	TCGA-EY-A1GI	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	TCGA-EY-A1GI	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	DO40978	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	DO40978	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	DO52412	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	DO52412	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	DO41211	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	DO41211	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.E2616K	DO41524	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7022
p.E2616K	DO41524	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7022
p.P2274H	TCGA-D1-A17H	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation rewiring degron network	0.25
p.P2274H	TCGA-D1-A17H	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation rewiring degron network	0.3056
p.P2274H	TCGA-D1-A17H	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.2778
p.P2274H	DO41847	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation rewiring degron network	0.25
p.P2274H	DO41847	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation rewiring degron network	0.3056
p.P2274H	DO41847	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.2778
p.D1978N	TCGA-D1-A17Q	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1976:1983	Mutation altering degron motif	0.6932
p.S2035L	TCGA-D1-A2G0	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation altering degron motif	0.7667
p.G2466W	TCGA-D3-A2JC	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation altering degron motif	0.7825
p.G2466W	DO47578	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation altering degron motif	0.7825
p.E2087K	TCGA-D3-A2JD	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2080:2087	Mutation altering degron motif	0.7022
p.E2087K	TCGA-D3-A2JD	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2084:2088	Mutation altering degron motif	0.7022
p.G2276W	TCGA-D3-A3CE	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7825
p.G2276W	DO37405	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7825
p.P1916S	TCGA-D3-A3MU	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation rewiring degron network	0.2778
p.P1916S	TCGA-D3-A3MU	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation rewiring degron network	0.25
p.P1916S	TCGA-D3-A3MU	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	1923:1927	Mutation rewiring degron network	0.1389
p.P1916S	DO47337	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation rewiring degron network	0.2778
p.P1916S	DO47337	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation rewiring degron network	0.25
p.P1916S	DO47337	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	1923:1927	Mutation rewiring degron network	0.1389
p.G2482E	TCGA-D3-A3MV	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation altering degron motif	0.7199
p.G2482E	DO37727	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation altering degron motif	0.7199
p.S1892F	TCGA-D3-A8GC	SKCM	TCGA	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.3056
p.S1892F	TCGA-D3-A8GC	SKCM	TCGA	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.25
p.S1892F	TCGA-D3-A8GC	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.1111
p.S1892F	DO50281	SKCM	ICGC	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.3056
p.S1892F	DO50281	SKCM	ICGC	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.25
p.S1892F	DO50281	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.1111
p.G2097S	TCGA-D3-A8GI	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2091:2098	Mutation altering degron motif	0.6993
p.T2266I	TCGA-D3-A8GI	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation altering degron motif	0.5966
p.T1936I	TCGA-D7-A4YV	STAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation altering degron motif	0.7078
p.T1821A	TCGA-D8-A1J8	BRCA	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.25
p.T1821A	DO1269	BRCA	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.25
p.P1951S	TCGA-D9-A149	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1942:1949	Mutation rewiring degron network	0.2778
p.P1951S	TCGA-D9-A149	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1953:1960	Mutation rewiring degron network	0.2778
p.P1951S	TCGA-D9-A149	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	1946:1950	Mutation rewiring degron network	0.3056
p.Q2138K	TCGA-DA-A1I1	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2137:2144	Mutation altering degron motif	0.6944
p.P2167H	TCGA-DA-A1I1	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation altering degron motif	0.7694
p.E2405K	TCGA-DA-A95Z	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2402:2409	Mutation altering degron motif	0.7022
p.E2405K	DO219481	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2402:2409	Mutation altering degron motif	0.7022
p.H2126R	TCGA-DD-AACV	LIHC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation altering degron motif	0.8244
p.T1939M	TCGA-DD-AACY	LIHC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation rewiring degron network	0.2778
p.T1939M	TCGA-DD-AACY	LIHC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1942:1949	Mutation rewiring degron network	0.25
p.T1939M	TCGA-DD-AACY	LIHC	TCGA	PITTT	DEG_SPOP_SBC_1	1946:1950	Mutation rewiring degron network	0.1389
p.T1939M	TCGA-UF-A7JH	HNSC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation rewiring degron network	0.2778
p.T1939M	TCGA-UF-A7JH	HNSC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1942:1949	Mutation rewiring degron network	0.25
p.T1939M	TCGA-UF-A7JH	HNSC	TCGA	PITTT	DEG_SPOP_SBC_1	1946:1950	Mutation rewiring degron network	0.1389
p.L1295F	TCGA-DD-AAEE	LIHC	TCGA	VLSTT	DEG_SPOP_SBC_1	1294:1298	Mutation altering degron motif	0.587
p.I1632V	TCGA-DD-AAVR	LIHC	TCGA	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7076
p.K1394M	TCGA-DD-AAVV	LIHC	TCGA	PPTTT	DEG_SPOP_SBC_1	1401:1405	Mutation substituting flanking lysine	0.25
p.D2270N	TCGA-DF-A2KU	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2264:2271	Mutation altering degron motif	0.6932
p.D2270N	TCGA-DF-A2KU	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2268:2272	Mutation altering degron motif	0.6932
p.R2491W	TCGA-DF-A2KU	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation rewiring degron network	0.2778
p.R2491W	TCGA-DF-A2KU	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation rewiring degron network	0.25
p.R2491W	TCGA-DF-A2KU	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation rewiring degron network	0.1389
p.R2491W	DO223286	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation rewiring degron network	0.2778
p.R2491W	DO223286	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation rewiring degron network	0.25
p.R2491W	DO223286	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation rewiring degron network	0.1389
p.P1891L	TCGA-DM-A0X9	COAD	TCGA	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.2778
p.P1891L	TCGA-DM-A0X9	COAD	TCGA	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.2222
p.P1891L	TCGA-DM-A0X9	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.0833
p.P1891L	DO8618	COAD	ICGC	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.2778
p.P1891L	DO8618	COAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.2222
p.P1891L	DO8618	COAD	ICGC	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation rewiring degron network	0.0833
p.G2817V	TCGA-DX-A6YQ	SARC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2816:2823	Mutation altering degron motif	0.7532
p.G2817V	DO220002	SARC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2816:2823	Mutation altering degron motif	0.7532
p.S2535F	TCGA-E2-A10B	BRCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2528:2535	Mutation altering degron motif	0.7982
p.S2535F	DO5843	BRCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2528:2535	Mutation altering degron motif	0.7982
p.H2566N	TCGA-E2-A14R	BRCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation altering degron motif	0.7423
p.H2566N	DO3822	BRCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation altering degron motif	0.7423
p.D2131N	TCGA-E6-A1LX	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation altering degron motif	0.6932
p.D2131N	TCGA-E6-A1LX	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2130:2134	Mutation altering degron motif	0.6932
p.E2788K	TCGA-E6-A1LX	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2781:2788	Mutation altering degron motif	0.7022
p.E2788K	DO41020	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2781:2788	Mutation altering degron motif	0.7022
p.G1902R	TCGA-EB-A5UM	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation altering degron motif	0.7568
p.G1902R	DO47282	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation altering degron motif	0.7568
p.D2107N	TCGA-EE-A29E	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2103:2110	Mutation altering degron motif	0.6932
p.D2107N	TCGA-EE-A29E	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2107:2111	Mutation altering degron motif	0.6932
p.P2051S	TCGA-EE-A29M	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2045:2052	Mutation altering degron motif	0.5641
p.E2231K	TCGA-EE-A2MR	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2229:2236	Mutation altering degron motif	0.7022
p.P2167L	TCGA-EE-A3AC	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation altering degron motif	0.7582
p.D2124N	TCGA-EE-A3J4	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation rewiring degron network	0.25
p.D2124N	TCGA-EE-A3J4	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation rewiring degron network	0.2778
p.D2124N	TCGA-EE-A3J4	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2130:2134	Mutation rewiring degron network	0.1667
p.D2124N	TCGA-FW-A3R5	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation rewiring degron network	0.25
p.D2124N	TCGA-FW-A3R5	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation rewiring degron network	0.2778
p.D2124N	TCGA-FW-A3R5	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2130:2134	Mutation rewiring degron network	0.1667
p.P1967L	TCGA-EE-A3JH	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation altering degron motif	0.7582
p.S2027W	TCGA-EK-A2RK	CESC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2022:2029	Mutation altering degron motif	0.7874
p.P2056H	TCGA-EM-A2CJ	THCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2045:2052	Mutation rewiring degron network	0.2222
p.P2056H	TCGA-EM-A2CJ	THCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2057:2064	Mutation rewiring degron network	0.3056
p.P2056H	TCGA-EM-A2CJ	THCA	TCGA	PITTT	DEG_SPOP_SBC_1	2061:2065	Mutation rewiring degron network	0.1944
p.P2020T	TCGA-EM-A2CN	THCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2011:2018	Mutation rewiring degron network	0.2778
p.P2020T	TCGA-EM-A2CN	THCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2022:2029	Mutation rewiring degron network	0.2778
p.P2020T	TCGA-EM-A2CN	THCA	TCGA	PITTT	DEG_SPOP_SBC_1	2015:2019	Mutation rewiring degron network	0.3056
p.Q1671H	TCGA-EO-A22U	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7582
p.Y1966C	TCGA-EO-A3AV	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation altering degron motif	0.7087
p.K2533N	TCGA-EO-A3B0	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2528:2535	Mutation altering degron motif	0.6918
p.K2533N	DO219773	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2528:2535	Mutation altering degron motif	0.6918
p.P2038H	TCGA-EO-A3KX	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation altering degron motif	0.7694
p.P2038H	TCGA-EO-A3KX	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2038:2042	Mutation altering degron motif	0.7694
p.T1926I	TCGA-EY-A215	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation altering degron motif	0.7078
p.T1926I	TCGA-EY-A215	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	1923:1927	Mutation altering degron motif	0.7078
p.V2577A	TCGA-EY-A2OP	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2574:2581	Mutation altering degron motif	0.6936
p.V2577A	DO42560	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2574:2581	Mutation altering degron motif	0.6936
p.G1738D	TCGA-EY-A548	UCEC	TCGA	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.G1738D	TCGA-EY-A548	UCEC	TCGA	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.0556
p.G1738D	DO48173	UCEC	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.G1738D	DO48173	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.0556
p.G1923S	TCGA-F4-6570	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation altering degron motif	0.6993
p.G1923S	TCGA-F4-6570	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	1923:1927	Mutation altering degron motif	0.6993
p.V2674I	TCGA-FI-A2D0	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation rewiring degron network	0.3056
p.V2674I	TCGA-FI-A2D0	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2678:2685	Mutation rewiring degron network	0.2222
p.V2674I	TCGA-FI-A2D0	UCEC	TCGA	PITTT	DEG_SPOP_SBC_1	2682:2686	Mutation rewiring degron network	0.1111
p.V2674I	DO43891	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation rewiring degron network	0.3056
p.V2674I	DO43891	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2678:2685	Mutation rewiring degron network	0.2222
p.V2674I	DO43891	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2682:2686	Mutation rewiring degron network	0.1111
p.A2807T	TCGA-FI-A2D0	UCEC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7139
p.A2807T	DO43891	UCEC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7139
p.K2451N	TCGA-FI-A2D5	UCEC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2448:2455	Mutation altering degron motif	0.6918
p.K2451N	DO41331	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2448:2455	Mutation altering degron motif	0.6918
p.G2258S	TCGA-FR-A726	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2252:2259	Mutation altering degron motif	0.6993
p.P2055L	TCGA-FW-A3R5	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2045:2052	Mutation rewiring degron network	0.25
p.P2055L	TCGA-FW-A3R5	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2057:2064	Mutation rewiring degron network	0.2778
p.P2055L	TCGA-FW-A3R5	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2061:2065	Mutation rewiring degron network	0.1667
p.D2353N	TCGA-FX-A48G	SARC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.2778
p.D2353N	TCGA-FX-A48G	SARC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation rewiring degron network	0.25
p.D2353N	TCGA-FX-A48G	SARC	TCGA	PITTT	DEG_SPOP_SBC_1	2360:2364	Mutation rewiring degron network	0.1389
p.D2353N	TCGA-WE-AAA0	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.2778
p.D2353N	TCGA-WE-AAA0	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation rewiring degron network	0.25
p.D2353N	TCGA-WE-AAA0	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2360:2364	Mutation rewiring degron network	0.1389
p.D2353N	DO220126	SARC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.2778
p.D2353N	DO220126	SARC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation rewiring degron network	0.25
p.D2353N	DO220126	SARC	ICGC	PITTT	DEG_SPOP_SBC_1	2360:2364	Mutation rewiring degron network	0.1389
p.D2353N	DO51294	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.2778
p.D2353N	DO51294	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2356:2363	Mutation rewiring degron network	0.25
p.D2353N	DO51294	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	2360:2364	Mutation rewiring degron network	0.1389
p.T2588M	TCGA-G2-AA3C	BLCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2586:2593	Mutation altering degron motif	0.6312
p.T2588M	DO51883	BLCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2586:2593	Mutation altering degron motif	0.6312
p.T2588M	DO233145	GACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2586:2593	Mutation altering degron motif	0.6312
p.V2586M	TCGA-G4-6320	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2586:2593	Mutation altering degron motif	0.7208
p.V2586M	DO8159	COAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2586:2593	Mutation altering degron motif	0.7208
p.T2030M	TCGA-G4-6628	COAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2022:2029	Mutation rewiring degron network	0.3056
p.T2030M	TCGA-G4-6628	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation rewiring degron network	0.2222
p.T2030M	TCGA-G4-6628	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2038:2042	Mutation rewiring degron network	0.1111
p.T2030M	ACH-000067	Brain Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2022:2029	Mutation rewiring degron network	0.3056
p.T2030M	ACH-000067	Brain Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation rewiring degron network	0.2222
p.T2030M	ACH-000067	Brain Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2038:2042	Mutation rewiring degron network	0.1111
p.R2389W	TCGA-G4-6628	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.25
p.R2389W	TCGA-G4-6628	COAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2390:2397	Mutation rewiring degron network	0.3056
p.R2389W	TCGA-G4-6628	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.2778
p.R2389W	DO10132	COAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.25
p.R2389W	DO10132	COAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2390:2397	Mutation rewiring degron network	0.3056
p.R2389W	DO10132	COAD	ICGC	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.2778
p.K2561N	TCGA-G9-6329	PRAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.25
p.K2561N	TCGA-G9-6329	PRAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation rewiring degron network	0.2778
p.K2561N	TCGA-G9-6329	PRAD	TCGA	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation rewiring degron network	0.1667
p.K2561N	DO36281	PRAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.25
p.K2561N	DO36281	PRAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation rewiring degron network	0.2778
p.K2561N	DO36281	PRAD	ICGC	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation rewiring degron network	0.1667
p.S2773N	TCGA-GF-A6C9	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2770:2777	Mutation altering degron motif	0.7069
p.S2773N	DO51254	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2770:2777	Mutation altering degron motif	0.7069
p.H1838Y	TCGA-GN-A266	SKCM	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1111
p.H1838Y	DO37432	SKCM	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1111
p.V2226A	TCGA-GN-A26A	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2222:2226	Mutation altering degron motif	0.6936
p.T2306I	TCGA-GN-A4U7	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation rewiring degron network	0.3056
p.T2306I	TCGA-GN-A4U7	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation rewiring degron network	0.2222
p.T2306I	TCGA-GN-A4U7	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation rewiring degron network	0.1111
p.T2306I	DO51258	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2298:2305	Mutation rewiring degron network	0.3056
p.T2306I	DO51258	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation rewiring degron network	0.2222
p.T2306I	DO51258	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation rewiring degron network	0.1111
p.R1922C	TCGA-GN-A8LK	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation altering degron motif	0.8301
p.R1922C	ACH-001566	Skin Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation altering degron motif	0.8301
p.G2698E	TCGA-GN-A8LK	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation rewiring degron network	0.2778
p.G2698E	TCGA-GN-A8LK	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2701:2708	Mutation rewiring degron network	0.25
p.G2698E	TCGA-GN-A8LK	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2705:2709	Mutation rewiring degron network	0.1389
p.G2698E	DO51259	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation rewiring degron network	0.2778
p.G2698E	DO51259	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2701:2708	Mutation rewiring degron network	0.25
p.G2698E	DO51259	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	2705:2709	Mutation rewiring degron network	0.1389
p.P2167S	TCGA-HU-A4G8	STAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation altering degron motif	0.6752
p.A2370T	TCGA-HU-A4H8	STAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation altering degron motif	0.7139
p.A2370T	DO47869	STAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation altering degron motif	0.7139
p.E2623K	TCGA-IB-7651	PAAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation altering degron motif	0.7022
p.E2623K	DO46657	PAAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation altering degron motif	0.7022
p.V2796A	TCGA-IB-7651	PAAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2793:2800	Mutation altering degron motif	0.6936
p.V2796A	DO46657	PAAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2793:2800	Mutation altering degron motif	0.6936
p.V2144M	TCGA-IB-A7M4	PAAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2137:2144	Mutation altering degron motif	0.7208
p.V2200G	TCGA-IZ-8196	KIRP	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2195:2202	Mutation altering degron motif	0.7532
p.V2200G	TCGA-IZ-8196	KIRP	TCGA	PITTT	DEG_SPOP_SBC_1	2199:2203	Mutation altering degron motif	0.7532
p.E2008Q	TCGA-JW-A5VL	CESC	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1999:2006	Mutation rewiring degron network	0.2778
p.E2008Q	TCGA-JW-A5VL	CESC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2011:2018	Mutation rewiring degron network	0.25
p.E2008Q	TCGA-JW-A5VL	CESC	TCGA	PITTT	DEG_SPOP_SBC_1	2015:2019	Mutation rewiring degron network	0.1389
p.T1628N	TCGA-KM-8440	KICH	TCGA	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.7055
p.T1628N	TCGA-KM-8440	KICH	TCGA	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7055
p.T1628N	DO220357	KICH	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.7055
p.T1628N	DO220357	KICH	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7055
p.T1914M	TCGA-L5-A4OI	ESCA	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.6312
p.F2156L	TCGA-MP-A4TC	LUAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2149:2156	Mutation altering degron motif	0.6981
p.F2156L	TCGA-MP-A4TC	LUAD	TCGA	PITTT	DEG_SPOP_SBC_1	2153:2157	Mutation altering degron motif	0.6981
p.P1910T	TCGA-MP-A4TJ	LUAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.7031
p.P1910T	DO45394	LUAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.7031
p.T1886S	TCGA-NH-A50T	COAD	TCGA	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1389
p.T1886S	TCGA-NH-A50T	COAD	TCGA	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.0833
p.T1886S	DO44086	COAD	ICGC	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1389
p.T1886S	DO44086	COAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.0833
p.G2108D	TCGA-NH-A5IV	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2103:2110	Mutation altering degron motif	0.7198
p.G2108D	TCGA-NH-A5IV	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2107:2111	Mutation altering degron motif	0.7198
p.C2342Y	TCGA-NH-A5IV	COAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2333:2340	Mutation rewiring degron network	0.2778
p.C2342Y	TCGA-NH-A5IV	COAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.2778
p.C2342Y	TCGA-NH-A5IV	COAD	TCGA	PITTT	DEG_SPOP_SBC_1	2337:2341	Mutation rewiring degron network	0.3056
p.C2342Y	DO49095	COAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2333:2340	Mutation rewiring degron network	0.2778
p.C2342Y	DO49095	COAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation rewiring degron network	0.2778
p.C2342Y	DO49095	COAD	ICGC	PITTT	DEG_SPOP_SBC_1	2337:2341	Mutation rewiring degron network	0.3056
p.P1690H	TCGA-PK-A5HB	ACC	TCGA	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation rewiring degron network	0.1667
p.P1690H	TCGA-PK-A5HB	ACC	TCGA	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.0556
p.P1690H	TCGA-PK-A5HB	ACC	TCGA	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.2778
p.P1690H	TCGA-PK-A5HB	ACC	TCGA	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation rewiring degron network	0.3056
p.G2778S	TCGA-R5-A7ZE	STAD	TCGA	PITTT	DEG_SPOP_SBC_1	2774:2778	Mutation altering degron motif	0.6993
p.G2778S	DO222340	STAD	ICGC	PITTT	DEG_SPOP_SBC_1	2774:2778	Mutation altering degron motif	0.6993
p.P2125L	TCGA-R5-A7ZI	STAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation rewiring degron network	0.2222
p.P2125L	TCGA-R5-A7ZI	STAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation rewiring degron network	0.3056
p.P2125L	TCGA-R5-A7ZI	STAD	TCGA	PITTT	DEG_SPOP_SBC_1	2130:2134	Mutation rewiring degron network	0.1944
p.G2567E	TCGA-RP-A693	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation altering degron motif	0.7199
p.G2567E	TCGA-RP-A693	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation altering degron motif	0.7199
p.G2567E	DO51268	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation altering degron motif	0.7199
p.G2567E	DO51268	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation altering degron motif	0.7199
p.A2752T	TCGA-UB-AA0V	LIHC	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7139
p.A2752T	TCGA-UB-AA0V	LIHC	TCGA	PITTT	DEG_SPOP_SBC_1	2751:2755	Mutation altering degron motif	0.7139
p.A2752T	DO52324	LIHC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7139
p.A2752T	DO52324	LIHC	ICGC	PITTT	DEG_SPOP_SBC_1	2751:2755	Mutation altering degron motif	0.7139
p.A2752T	ACH-002199	Kidney Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation altering degron motif	0.7139
p.A2752T	ACH-002199	Kidney Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2751:2755	Mutation altering degron motif	0.7139
p.N2681K	TCGA-VQ-A91U	STAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2678:2685	Mutation altering degron motif	0.6918
p.N2681K	DO51787	STAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2678:2685	Mutation altering degron motif	0.6918
p.V1970L	TCGA-VQ-A91Z	STAD	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1965:1972	Mutation altering degron motif	0.6765
p.V1970L	TCGA-VQ-A91Z	STAD	TCGA	PITTT	DEG_SPOP_SBC_1	1969:1973	Mutation altering degron motif	0.6765
p.P2689S	TCGA-W3-A825	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation altering degron motif	0.6752
p.P2689S	DO51272	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation altering degron motif	0.6752
p.G1984S	TCGA-W3-AA1V	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	1976:1983	Mutation rewiring degron network	0.3056
p.G1984S	TCGA-W3-AA1V	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	1988:1995	Mutation rewiring degron network	0.2222
p.G1984S	TCGA-W3-AA1V	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	1992:1996	Mutation rewiring degron network	0.1111
p.P2534S	TCGA-WE-A8K5	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2528:2535	Mutation altering degron motif	0.5641
p.P2534S	DO51282	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2528:2535	Mutation altering degron motif	0.5641
p.R2463K	TCGA-WE-AAA0	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation altering degron motif	0.7237
p.R2463K	DO51294	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation altering degron motif	0.7237
p.S2013P	TCGA-XV-AAZY	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2011:2018	Mutation altering degron motif	0.6752
p.E2467K	TCGA-YG-AA3O	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.3056
p.E2467K	TCGA-YG-AA3O	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.2222
p.E2467K	TCGA-YG-AA3O	SKCM	TCGA	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1111
p.E2467K	DO51299	SKCM	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.3056
p.E2467K	DO51299	SKCM	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.2222
p.E2467K	DO51299	SKCM	ICGC	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1111
p.G2108S	TCGA-YZ-A985	UVM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2103:2110	Mutation altering degron motif	0.6993
p.G2108S	TCGA-YZ-A985	UVM	TCGA	PITTT	DEG_SPOP_SBC_1	2107:2111	Mutation altering degron motif	0.6993
p.S2244F	TCGA-Z2-AA3V	SKCM	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2241:2248	Mutation altering degron motif	0.7982
p.P1836L	TCGA-Z6-A9VB	ESCA	TCGA	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1667
p.G2315R	TCGA-ZF-AA4N	BLCA	TCGA	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation altering degron motif	0.7568
p.G2315R	TCGA-ZF-AA4N	BLCA	TCGA	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation altering degron motif	0.7568
p.G2315R	DO219082	BLCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation altering degron motif	0.7568
p.G2315R	DO219082	BLCA	ICGC	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation altering degron motif	0.7568
p.D2161N	TCGA-ZH-A8Y4	CHOL	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	2160:2167	Mutation altering degron motif	0.6932
p.A1757P	DO48389	BLCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7503
p.A1757P	DO48390	BLCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7503
p.A1757P	DO48370	BLCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7503
p.A1757P	DO229502	SKCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7503
p.A1757P	DO229232	THCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7503
p.P2513H	DO225280	BRCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation rewiring degron network	0.3056
p.P2513H	DO225280	BRCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation rewiring degron network	0.2222
p.P2513H	DO225280	BRCA	ICGC	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1111
p.P1634A	DO3293	BRCA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation rewiring degron network	0.25
p.P1634A	DO3293	BRCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1620:1624	Mutation rewiring degron network	0.0556
p.P1634A	DO3293	BRCA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation rewiring degron network	0.2778
p.P1634A	DO3293	BRCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.2778
p.P1634A	DO3293	BRCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.0556
p.H1904R	DO222830	BTCA	ICGC	PITTT	DEG_SPOP_SBC_1	1900:1904	Mutation altering degron motif	0.8244
p.G2690V	DO222990	BTCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2689:2696	Mutation altering degron motif	0.7532
p.A2377T	DO229364	BTCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation rewiring degron network	0.25
p.A2377T	DO229364	BTCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.2778
p.A2377T	DO229364	BTCA	ICGC	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.1667
p.A2377T	ACH-002287	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2367:2374	Mutation rewiring degron network	0.25
p.A2377T	ACH-002287	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.2778
p.A2377T	ACH-002287	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.1667
p.V1638G	DO223362	CLLE	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7532
p.V1638G	DO232524	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7532
p.V1638G	DO232683	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7532
p.V1638G	DO232613	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7532
p.T1564S	DO6620	CLLE	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.25
p.T1564S	DO6620	CLLE	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.0833
p.T1564S	DO229003	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.25
p.T1564S	DO229003	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.0833
p.T1564S	DO51021	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.25
p.T1564S	DO51021	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.0833
p.T1564S	DO229053	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.25
p.T1564S	DO229053	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.0833
p.T1564S	DO229061	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.25
p.T1564S	DO229061	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.0833
p.T1560P	DO223476	CLLE	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1560P	DO224685	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1560P	DO222553	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1560P	DO222715	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1560P	DO51025	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1560P	DO51026	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1560P	DO234126	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7031
p.T1711M	DO6531	CLLE	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO224616	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO224628	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO224739	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO222737	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO222864	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO222866	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO222888	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO50980	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO50977	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1711M	DO51033	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation altering degron motif	0.7423
p.T1702S	DO6561	CLLE	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO224744	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO222778	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO222829	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO222842	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO51023	LAML	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO51008	LAML	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO229027	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO229053	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1702S	DO68928	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6005
p.T1728S	DO6372	CLLE	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7116
p.T1728S	DO228771	GACA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7116
p.T1728S	DO220906	MELA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7116
p.T1728S	DO51469	PACA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7116
p.T1728S	DO229268	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7116
p.T1728S	DO229211	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7116
p.S1502T	DO6394	CLLE	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1944
p.S1502T	DO6394	CLLE	ICGC	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.0833
p.P1721L	DO7124	CLLE	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO7124	CLLE	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO7124	CLLE	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO224701	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO224701	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO224701	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO224739	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO224739	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO224739	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO224744	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO224744	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO224744	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO222829	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO222829	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO222829	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO51020	LAML	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO51020	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO51020	LAML	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO229055	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO229055	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO229055	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO229062	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO229062	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO229062	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721L	DO229245	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721L	DO229245	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721L	DO229245	THCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.Y2784F	DO7190	CLLE	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2781:2788	Mutation altering degron motif	0.7528
p.P1724Q	DO230330	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.P1724Q	DO230330	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1944
p.A2344T	DO227802	COCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2344:2351	Mutation altering degron motif	0.7139
p.A1644P	DO224645	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7503
p.A1644P	DO228940	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7503
p.A1644P	DO228985	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7503
p.A1644P	DO229211	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7503
p.A1644P	DO229227	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7503
p.S1584T	DO224645	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO224726	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO50978	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO228955	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO228988	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO229144	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO229272	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.S1584T	DO229089	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1389
p.T1652M	DO224655	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652M	DO222788	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652M	DO222733	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652M	DO222891	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1649S	DO224655	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0833
p.T1649S	DO224655	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.T1649S	DO222788	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0833
p.T1649S	DO222788	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.T1649S	DO222733	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0833
p.T1649S	DO222733	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.T1649S	DO222891	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0833
p.T1649S	DO222891	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.T1649S	DO50998	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0833
p.T1649S	DO50998	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.T1649S	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0833
p.T1649S	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.T1683M	DO224661	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.25
p.T1683M	DO224661	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.3056
p.T1683M	DO224661	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation rewiring degron network	0.1111
p.T1683M	DO224801	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.25
p.T1683M	DO224801	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.3056
p.T1683M	DO224801	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation rewiring degron network	0.1111
p.T1683M	DO232594	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.25
p.T1683M	DO232594	PBCA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.3056
p.T1683M	DO232594	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation rewiring degron network	0.1111
p.P1721T	DO224689	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721T	DO224689	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721T	DO224689	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721T	DO222794	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721T	DO222794	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721T	DO222794	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721T	DO228945	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721T	DO228945	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721T	DO228945	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1721T	DO229059	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1389
p.P1721T	DO229059	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.0833
p.P1721T	DO229059	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.G1738S	DO224620	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.G1738S	DO224620	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.0556
p.G1738S	DO50956	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.G1738S	DO50956	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.0556
p.G1738S	DO222532	MELA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.G1738S	DO222532	MELA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.0556
p.G1738S	DO229242	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.2222
p.G1738S	DO229242	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.0556
p.T1636S	DO224628	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO222746	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO222765	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO222715	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO50999	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO51019	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO51007	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO51004	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO229061	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1636S	DO229257	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.T1750N	DO224639	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO222528	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO222571	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO222891	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO222840	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO222849	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229013	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO228581	GACA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO225407	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO225412	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO225423	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO51034	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO49680	LIAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229062	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO50737	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229204	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229208	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229216	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1750N	DO229250	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation altering degron motif	0.7055
p.T1744P	DO224766	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO224766	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO224739	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO224739	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO222888	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO222888	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO225412	LAML	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO225412	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO228950	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO228950	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO228896	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO228896	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO229046	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO229046	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO229053	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO229053	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO229140	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO229140	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744P	DO229232	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744P	DO229232	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.G1577S	DO224761	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation altering degron motif	0.6993
p.G1577S	DO228955	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation altering degron motif	0.6993
p.G1577S	DO229046	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation altering degron motif	0.6993
p.G1577S	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation altering degron motif	0.6993
p.S1665L	DO224721	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO222856	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO229010	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO51042	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO228919	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO229036	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO228012	SKCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO229199	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.S1665L	DO231322	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.P1608H	DO224739	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1944
p.P1608H	DO232785	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1944
p.P1608H	DO232532	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1944
p.P1675L	DO224739	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.P1675L	DO224739	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.3056
p.P1675L	DO224739	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.0833
p.T1652P	DO224744	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652P	DO228918	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652P	DO228922	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652P	DO228937	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652P	DO228946	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652P	DO229053	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652P	DO229060	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1614M	DO224757	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation altering degron motif	0.7423
p.T1614M	DO222798	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation altering degron motif	0.7423
p.T1606M	DO224801	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606M	DO222846	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606M	DO229055	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606M	DO229248	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.G1763S	DO224817	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.G1763S	DO222849	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.G1763S	DO229010	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.G1763S	DO229013	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.G1763S	DO229016	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.G1763S	DO229003	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.G1763S	DO229005	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.2222
p.I1442T	DO222585	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation altering degron motif	0.5966
p.S2493G	DO222528	COCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation rewiring degron network	0.2222
p.S2493G	DO222528	COCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation rewiring degron network	0.3056
p.S2493G	DO222528	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation rewiring degron network	0.1944
p.S2493G	DO230550	LUSC	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation rewiring degron network	0.2222
p.S2493G	DO230550	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation rewiring degron network	0.3056
p.S2493G	DO230550	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation rewiring degron network	0.1944
p.S1639T	DO222553	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.S1639T	DO222755	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.S1639T	DO222782	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.S1639T	DO229051	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.S1639T	DO229245	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.S1639T	DO229092	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7116
p.P1675T	DO222571	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.P1675T	DO222571	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.3056
p.P1675T	DO222571	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.0833
p.P1675T	DO49531	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.P1675T	DO49531	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.3056
p.P1675T	DO49531	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.0833
p.P1675T	DO229024	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.P1675T	DO229024	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.3056
p.P1675T	DO229024	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.0833
p.P1675T	DO229006	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.25
p.P1675T	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.3056
p.P1675T	DO229006	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.0833
p.S1698T	DO222741	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.7116
p.S1698T	DO228903	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.7116
p.S1698T	DO229053	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.7116
p.S1698T	DO229242	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.7116
p.T1672I	DO222752	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO222800	COCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO225415	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO228912	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO228928	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO228945	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO228961	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO229028	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO229053	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO229058	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO232663	PBCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO231290	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1672I	DO231319	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7078
p.T1606P	DO222752	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO222729	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO51021	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO228948	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO228985	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO229061	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1606P	DO229248	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1389
p.T1413M	DO222774	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1401:1405	Mutation rewiring degron network	0.1111
p.T1413M	DO222774	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1417:1421	Mutation rewiring degron network	0.2222
p.P1650T	DO222788	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0556
p.P1650T	DO222788	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2778
p.P1650T	DO222891	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0556
p.P1650T	DO222891	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2778
p.P1650T	DO50998	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0556
p.P1650T	DO50998	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2778
p.P1650T	DO50991	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0556
p.P1650T	DO50991	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2778
p.P1650T	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.0556
p.P1650T	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2778
p.T1604M	DO222706	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.0833
p.T1610S	DO222729	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.25
p.T1610S	DO222729	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1620:1624	Mutation rewiring degron network	0.0556
p.T1560M	DO222869	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7423
p.T1560M	DO229085	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.7423
p.P1678A	DO222874	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation altering degron motif	0.7503
p.S1725T	DO222829	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.25
p.S1725T	DO222829	COCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1667
p.S1725T	DO229053	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.25
p.S1725T	DO229053	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1667
p.S1725T	DO229055	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.25
p.S1725T	DO229055	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1667
p.S1725T	DO229061	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.25
p.S1725T	DO229061	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1667
p.S1725T	DO229006	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.25
p.S1725T	DO229006	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1667
p.V1746L	DO229013	COCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2778
p.V1746L	DO229013	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.0833
p.P1909L	DO229016	COCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.6471
p.T1764S	DO229003	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1944
p.P1732T	DO229003	COCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7031
p.P1535S	DO227432	EOPC	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation altering degron motif	0.5641
p.T1531I	DO227432	EOPC	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation rewiring degron network	0.0833
p.T1531I	DO227432	EOPC	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation rewiring degron network	0.25
p.T1531I	DO227432	EOPC	ICGC	PPTTT	DEG_SPOP_SBC_1	1541:1545	Mutation rewiring degron network	0.0556
p.T1664I	DO10809	EOPC	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.2222
p.C2492G	DO50346	ESAD	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2482:2489	Mutation rewiring degron network	0.25
p.C2492G	DO50346	ESAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2494:2501	Mutation rewiring degron network	0.2778
p.C2492G	DO50346	ESAD	ICGC	PITTT	DEG_SPOP_SBC_1	2498:2502	Mutation rewiring degron network	0.1667
p.V2311I	DO234377	ESAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation altering degron motif	0.7076
p.T1630A	DO218242	GACA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.6028
p.T1630A	DO218242	GACA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7139
p.T1630A	DO229253	THCA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.6028
p.T1630A	DO229253	THCA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7139
p.M2547L	DO233284	GACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.711
p.M2547L	DO233284	GACA	ICGC	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation altering degron motif	0.711
p.M2547L	DO232846	NACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.711
p.M2547L	DO232846	NACA	ICGC	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation altering degron motif	0.711
p.T1893K	DO233226	GACA	ICGC	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation altering degron motif	0.7306
p.T1744S	DO233766	GACA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744S	DO233766	GACA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.T1744S	DO229061	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.0556
p.T1744S	DO229061	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.2222
p.C2633R	DO233944	GACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation altering degron motif	0.8301
p.G2317S	DO220549	KICH	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2310:2317	Mutation altering degron motif	0.6993
p.G2317S	DO220549	KICH	ICGC	PITTT	DEG_SPOP_SBC_1	2314:2318	Mutation altering degron motif	0.6993
p.T1504M	DO230659	LAML	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.25
p.T1504M	DO230659	LAML	ICGC	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.1389
p.T1504M	DO49087	PACA	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.25
p.T1504M	DO49087	PACA	ICGC	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.1389
p.T1504M	DO32819	PACA	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.25
p.T1504M	DO32819	PACA	ICGC	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.1389
p.T1643P	DO50990	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.25
p.T1643P	DO50990	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.3056
p.P1673L	DO50987	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.3056
p.P1673L	DO50987	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.25
p.T1569M	DO225407	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.T1569M	DO225407	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1569M	DO225417	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.T1569M	DO225417	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1569M	DO225425	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.T1569M	DO225425	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1569M	DO225429	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.T1569M	DO225429	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1569M	DO227558	PACA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.T1569M	DO227558	PACA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1569M	DO229234	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.T1569M	DO229234	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1431P	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1417:1421	Mutation rewiring degron network	0.0556
p.T1431P	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1424:1428	Mutation rewiring degron network	0.25
p.T1431P	DO51018	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1433:1437	Mutation rewiring degron network	0.2778
p.T1431P	DO51018	LAML	ICGC	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation rewiring degron network	0.0556
p.A1631P	DO51019	LAML	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.7503
p.A1631P	DO51019	LAML	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7503
p.A1631P	DO228911	LICA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.7503
p.A1631P	DO228911	LICA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7503
p.A1631P	DO228921	LICA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.7503
p.A1631P	DO228921	LICA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7503
p.A1631P	DO229035	LICA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1625:1631	Mutation altering degron motif	0.7503
p.A1631P	DO229035	LICA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation altering degron motif	0.7503
p.T1550N	DO51005	LAML	ICGC	PITPPTS	DEG_SCF_FBW7_1	1546:1552	Mutation altering degron motif	0.7055
p.T1550N	DO51005	LAML	ICGC	PPTST	DEG_SPOP_SBC_1	1549:1553	Mutation altering degron motif	0.7055
p.T1404P	DO231140	LAML	ICGC	PPTTT	DEG_SPOP_SBC_1	1401:1405	Mutation altering degron motif	0.7031
p.T1670N	DO228230	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation altering degron motif	0.7055
p.W2557C	DO228264	LICA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation altering degron motif	0.7
p.P1480S	DO228902	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1472:1476	Mutation rewiring degron network	0.2222
p.T1652I	DO228905	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652I	DO228938	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1652I	DO228947	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.S1698P	DO228908	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6752
p.S1698P	DO228937	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6752
p.S1698P	DO228974	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6752
p.S1698P	DO228993	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6752
p.S1698P	DO229040	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation altering degron motif	0.6752
p.S1740T	DO228911	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1667
p.S1740T	DO228911	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.1111
p.Q1707H	DO228916	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation rewiring degron network	0.1944
p.Q1707H	DO228916	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.3056
p.Q1707H	DO228916	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.1111
p.S1583P	DO228918	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1667
p.S1583P	DO229061	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1667
p.T1654I	DO228945	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1667
p.T1654I	DO228981	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1667
p.G1715C	DO228952	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation altering degron motif	0.76
p.T1623S	DO228950	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1620:1624	Mutation altering degron motif	0.6005
p.T1623S	DO229024	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1620:1624	Mutation altering degron motif	0.6005
p.T1623S	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1620:1624	Mutation altering degron motif	0.6005
p.T1527P	DO228899	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation rewiring degron network	0.1944
p.T1527P	DO228899	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation rewiring degron network	0.1389
p.T1527P	DO229053	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation rewiring degron network	0.1944
p.T1527P	DO229053	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation rewiring degron network	0.1389
p.P1607S	DO228961	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1667
p.P1607S	DO229049	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation rewiring degron network	0.1667
p.T1636A	DO228974	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7139
p.P1676S	DO229029	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation altering degron motif	0.6752
p.P1676S	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation altering degron motif	0.6752
p.L1518P	DO229024	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation altering degron motif	0.7582
p.L1518P	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation altering degron motif	0.7582
p.P1653S	DO229024	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1944
p.P1653S	DO229049	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1944
p.P1653S	DO229062	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1944
p.P1713H	DO229024	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.3056
p.P1713H	DO229024	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.P1713H	DO229006	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.3056
p.P1713H	DO229006	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.2778
p.T1561S	DO229024	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.6005
p.T1561S	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation altering degron motif	0.6005
p.P1654H	DO229024	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1667
p.P1654H	DO229006	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1667
p.G1692S	DO229027	LICA	ICGC	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation altering degron motif	0.6993
p.A1513T	DO229047	LICA	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation altering degron motif	0.7139
p.A1513T	DO229047	LICA	ICGC	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation altering degron motif	0.7139
p.Q1765H	DO229051	LICA	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1667
p.T1728I	DO229058	LICA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation altering degron motif	0.7078
p.S1817T	DO229061	LICA	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.S1817T	DO229140	THCA	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.S1817T	DO229088	THCA	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.S1817T	DO231475	THCA	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.T1715S	DO229060	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation altering degron motif	0.7116
p.P1688S	DO229006	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation altering degron motif	0.6752
p.R2809S	DO50797	LICA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.7427
p.P1448S	DO50970	LICA	ICGC	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation rewiring degron network	0.25
p.P1448S	DO50970	LICA	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation rewiring degron network	0.0833
p.P2327S	DO50970	LICA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2321:2328	Mutation altering degron motif	0.5641
p.C2325S	DO50905	LICA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2321:2328	Mutation altering degron motif	0.7541
p.K1395M	DO223912	LIHC	ICGC	PPTTT	DEG_SPOP_SBC_1	1401:1405	Mutation rewiring degron network	0.1667
p.L1296F	DO52270	LIHC	ICGC	VLSTT	DEG_SPOP_SBC_1	1294:1298	Mutation altering degron motif	0.6981
p.T1656N	DO23116	LINC	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1111
p.S1583L	DO231848	LINC	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.1667
p.T1527I	DO45199	LIRI	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation rewiring degron network	0.1944
p.T1527I	DO45199	LIRI	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation rewiring degron network	0.1389
p.G2614V	DO25797	LUAD	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.7532
p.G2614V	DO25797	LUAD	ICGC	PITTT	DEG_SPOP_SBC_1	2613:2617	Mutation altering degron motif	0.7532
p.P1767L	DO26414	LUAD	ICGC	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation rewiring degron network	0.1111
p.V2522I	DO230934	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation altering degron motif	0.7076
p.V2522I	DO230934	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7076
p.V2522I	DO224581	LUSC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation altering degron motif	0.7076
p.V2522I	DO224581	LUSC	ICGC	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7076
p.V2522I	DO51518	PACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation altering degron motif	0.7076
p.V2522I	DO51518	PACA	ICGC	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7076
p.V2522I	ACH-000999	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation altering degron motif	0.7076
p.V2522I	ACH-000999	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation altering degron motif	0.7076
p.A2340D	DO220844	MELA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2333:2340	Mutation altering degron motif	0.7793
p.A2340D	DO220844	MELA	ICGC	PITTT	DEG_SPOP_SBC_1	2337:2341	Mutation altering degron motif	0.7793
p.P2294S	DO220877	MELA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2287:2294	Mutation altering degron motif	0.6752
p.P2294S	DO220877	MELA	ICGC	PITTT	DEG_SPOP_SBC_1	2291:2295	Mutation altering degron motif	0.6752
p.P2800S	DO220886	MELA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2793:2800	Mutation altering degron motif	0.6752
p.P2800S	DO220886	MELA	ICGC	PITTT	DEG_SPOP_SBC_1	2797:2801	Mutation altering degron motif	0.6752
p.P1466L	DO220885	MELA	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation rewiring degron network	0.1944
p.P1466L	DO220885	MELA	ICGC	PPTTT	DEG_SPOP_SBC_1	1472:1476	Mutation rewiring degron network	0.1667
p.P1500S	DO220890	MELA	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1389
p.P1835L	DO222402	MELA	ICGC	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1944
p.P2576S	DO222420	MELA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2574:2581	Mutation altering degron motif	0.5641
p.T1555I	DO222510	MELA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1546:1552	Mutation rewiring degron network	0.25
p.T1555I	DO222510	MELA	ICGC	PPTTT	DEG_SPOP_SBC_1	1541:1545	Mutation rewiring degron network	0.0556
p.T1555I	DO222510	MELA	ICGC	PPTST	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.2778
p.T1555I	DO222510	MELA	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.2778
p.G2550E	DO232832	NACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation rewiring degron network	0.25
p.G2550E	DO232832	NACA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.3056
p.G2550E	DO232832	NACA	ICGC	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation rewiring degron network	0.2778
p.C2552Y	DO232849	NACA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation altering degron motif	0.7087
p.V1569M	DO46593	OV	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.V1569M	DO46593	OV	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.V1569M	DO46769	PAEN	ICGC	PPTTT	DEG_SPOP_SBC_1	1557:1561	Mutation rewiring degron network	0.1111
p.V1569M	DO46769	PAEN	ICGC	PPTTT	DEG_SPOP_SBC_1	1573:1577	Mutation rewiring degron network	0.2222
p.T1718S	DO46342	OV	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation altering degron motif	0.6005
p.C2396Y	DO46325	OV	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2390:2397	Mutation altering degron motif	0.7087
p.L1518V	DO28521	OV	ICGC	PPTTT	DEG_SPOP_SBC_1	1518:1522	Mutation altering degron motif	0.6765
p.T2720M	DO35158	PACA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.3056
p.T2720M	DO35158	PACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation rewiring degron network	0.2222
p.T2720M	DO35158	PACA	ICGC	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation rewiring degron network	0.1111
p.P2549T	DO35460	PACA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation rewiring degron network	0.2778
p.P2549T	DO35460	PACA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.2778
p.P2549T	DO35460	PACA	ICGC	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation rewiring degron network	0.3056
p.A2508T	DO228138	PBCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation altering degron motif	0.7139
p.P1642A	DO232732	PBCA	ICGC	PPTST	DEG_SPOP_SBC_1	1628:1632	Mutation rewiring degron network	0.0556
p.P1642A	DO232732	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation rewiring degron network	0.2778
p.P1642A	DO232732	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2778
p.E2559K	DO232869	PBCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2551:2558	Mutation rewiring degron network	0.3056
p.E2559K	DO232869	PBCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation rewiring degron network	0.2222
p.E2559K	DO232869	PBCA	ICGC	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation rewiring degron network	0.1111
p.T1706M	DO232883	PBCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation rewiring degron network	0.2222
p.T1706M	DO232883	PBCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.2778
p.T1706M	DO232883	PBCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.0833
p.T1706M	DO232593	PBCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation rewiring degron network	0.2222
p.T1706M	DO232593	PBCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.2778
p.T1706M	DO232593	PBCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.0833
p.T1706M	DO71492	THCA	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation rewiring degron network	0.2222
p.T1706M	DO71492	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	1708:1712	Mutation rewiring degron network	0.2778
p.T1706M	DO71492	THCA	ICGC	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation rewiring degron network	0.0833
p.P1438S	DO232552	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1424:1428	Mutation rewiring degron network	0.0556
p.P1438S	DO232552	PBCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1433:1437	Mutation rewiring degron network	0.3056
p.P1438S	DO232552	PBCA	ICGC	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation rewiring degron network	0.25
p.P1448L	DO233484	PRAD	ICGC	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation rewiring degron network	0.25
p.P1448L	DO233484	PRAD	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation rewiring degron network	0.0833
p.P1448L	DO233464	PRAD	ICGC	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation rewiring degron network	0.25
p.P1448L	DO233464	PRAD	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation rewiring degron network	0.0833
p.S2723L	DO37259	READ	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.2222
p.S2723L	DO37259	READ	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation rewiring degron network	0.3056
p.S2723L	DO37259	READ	ICGC	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation rewiring degron network	0.1944
p.S2295P	DO219881	SKCA	ICGC	PITTT	DEG_SPOP_SBC_1	2291:2295	Mutation altering degron motif	0.6752
p.S1460T	DO229470	SKCA	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation altering degron motif	0.7116
p.S1460T	DO218847	SKCA	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation altering degron motif	0.7116
p.L1416P	DO218851	SKCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1417:1421	Mutation rewiring degron network	0.3056
p.L1416P	DO218851	SKCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1424:1428	Mutation rewiring degron network	0.1111
p.I1459T	DO218847	SKCA	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation altering degron motif	0.7078
p.I1459T	DO229510	SKCA	ICGC	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation altering degron motif	0.7078
p.V2291G	DO227681	SKCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2287:2294	Mutation altering degron motif	0.7532
p.V2291G	DO227681	SKCA	ICGC	PITTT	DEG_SPOP_SBC_1	2291:2295	Mutation altering degron motif	0.7532
p.T1735A	DO37659	SKCM	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.3056
p.S1740N	DO38663	STAD	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1667
p.S1740N	DO38663	STAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.1111
p.P1690L	DO38187	STAD	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1696:1702	Mutation rewiring degron network	0.1667
p.P1690L	DO38187	STAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.0556
p.P1690L	DO38187	STAD	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.2778
p.P1690L	DO38187	STAD	ICGC	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation rewiring degron network	0.3056
p.Q2423P	DO229253	THCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2413:2420	Mutation rewiring degron network	0.25
p.Q2423P	DO229253	THCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2425:2432	Mutation rewiring degron network	0.2778
p.Q2423P	DO229253	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	2429:2433	Mutation rewiring degron network	0.1667
p.G2445D	DO229268	THCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2436:2443	Mutation rewiring degron network	0.2778
p.G2445D	DO229268	THCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2448:2455	Mutation rewiring degron network	0.25
p.G2445D	DO229268	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	2452:2456	Mutation rewiring degron network	0.1389
p.T1541S	DO229275	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1541:1545	Mutation altering degron motif	0.7116
p.P1540S	DO229208	THCA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1546:1552	Mutation rewiring degron network	0.1667
p.P1540S	DO229208	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation rewiring degron network	0.2778
p.P1540S	DO229208	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1541:1545	Mutation rewiring degron network	0.3056
p.P1540S	DO229208	THCA	ICGC	PPTST	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.0833
p.P1540S	DO229245	THCA	ICGC	PITPPTS	DEG_SCF_FBW7_1	1546:1552	Mutation rewiring degron network	0.1667
p.P1540S	DO229245	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1534:1538	Mutation rewiring degron network	0.2778
p.P1540S	DO229245	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1541:1545	Mutation rewiring degron network	0.3056
p.P1540S	DO229245	THCA	ICGC	PPTST	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.0833
p.W2388C	DO229216	THCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.2778
p.W2388C	DO229216	THCA	ICGC	VTPTPTPT	DEG_SCF_FBW7_1	2390:2397	Mutation rewiring degron network	0.2778
p.W2388C	DO229216	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.3056
p.P1425S	DO229213	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1424:1428	Mutation altering degron motif	0.5641
p.S1423R	DO229227	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1417:1421	Mutation rewiring degron network	0.2778
p.S1423R	DO229227	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1424:1428	Mutation rewiring degron network	0.3056
p.S1423R	DO229227	THCA	ICGC	PPTTT	DEG_SPOP_SBC_1	1433:1437	Mutation rewiring degron network	0.0556
p.A2340V	DO229245	THCA	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2333:2340	Mutation altering degron motif	0.6936
p.A2340V	DO229245	THCA	ICGC	PITTT	DEG_SPOP_SBC_1	2337:2341	Mutation altering degron motif	0.6936
p.S1502I	DO42312	UCEC	ICGC	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1944
p.S1502I	DO42312	UCEC	ICGC	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.0833
p.G1682D	DO41241	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.0556
p.G1682D	DO41241	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1676:1680	Mutation rewiring degron network	0.2778
p.G1682D	DO41241	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	1684:1688	Mutation rewiring degron network	0.2778
p.G1682D	DO41241	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1691:1695	Mutation rewiring degron network	0.0833
p.Q1638H	DO43755	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1636:1640	Mutation altering degron motif	0.7582
p.K1742N	DO41458	UCEC	ICGC	MTTPSPT	DEG_SCF_FBW7_1	1728:1734	Mutation rewiring degron network	0.1111
p.K1742N	DO41458	UCEC	ICGC	PPTTT	DEG_SPOP_SBC_1	1748:1752	Mutation rewiring degron network	0.1667
p.G2454S	DO42673	UCEC	ICGC	PTTTPITT	DEG_SCF_FBW7_1	2448:2455	Mutation altering degron motif	0.6993
p.G2454S	DO42673	UCEC	ICGC	PITTT	DEG_SPOP_SBC_1	2452:2456	Mutation altering degron motif	0.6993
p.Q2382E	ACH-000130	Leukemia	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation altering degron motif	0.6744
p.E2769V	ACH-000197	Leukemia	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2758:2765	Mutation rewiring degron network	0.2222
p.E2769V	ACH-000197	Leukemia	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2770:2777	Mutation rewiring degron network	0.3056
p.E2769V	ACH-000197	Leukemia	CCLE	PITTT	DEG_SPOP_SBC_1	2774:2778	Mutation rewiring degron network	0.1944
p.S1817R	ACH-000204	Myeloma	CCLE	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1389
p.H2642L	ACH-000250	Kidney Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2632:2639	Mutation rewiring degron network	0.25
p.H2642L	ACH-000250	Kidney Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2643:2650	Mutation rewiring degron network	0.3056
p.H2642L	ACH-000250	Kidney Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2636:2640	Mutation rewiring degron network	0.2778
p.R2204T	ACH-000290	Lung Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2195:2202	Mutation rewiring degron network	0.2778
p.R2204T	ACH-000290	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2206:2213	Mutation rewiring degron network	0.2778
p.R2204T	ACH-000290	Lung Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2199:2203	Mutation rewiring degron network	0.3056
p.R2204T	ACH-002369	Non-Cancerous	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2195:2202	Mutation rewiring degron network	0.2778
p.R2204T	ACH-002369	Non-Cancerous	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2206:2213	Mutation rewiring degron network	0.2778
p.R2204T	ACH-002369	Non-Cancerous	CCLE	PITTT	DEG_SPOP_SBC_1	2199:2203	Mutation rewiring degron network	0.3056
p.T1716R	ACH-000291	Ovarian Cancer	CCLE	PSSTT	DEG_SPOP_SBC_1	1715:1719	Mutation altering degron motif	0.7876
p.I1816F	ACH-000464	Brain Cancer	CCLE	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1111
p.S1915F	ACH-000491	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation rewiring degron network	0.3056
p.S1915F	ACH-000491	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation rewiring degron network	0.2222
p.S1915F	ACH-000491	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	1923:1927	Mutation rewiring degron network	0.1111
p.T1482P	ACH-000528	Lung Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1472:1476	Mutation rewiring degron network	0.1667
p.P1934S	ACH-000568	Breast Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation altering degron motif	0.5641
p.P1617L	ACH-000620	Liver Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1613:1617	Mutation altering degron motif	0.7582
p.R2389L	ACH-000675	Lung Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation rewiring degron network	0.25
p.R2389L	ACH-000675	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2390:2397	Mutation rewiring degron network	0.3056
p.R2389L	ACH-000675	Lung Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation rewiring degron network	0.2778
p.R2805C	ACH-000678	Gastric Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2804:2811	Mutation altering degron motif	0.8301
p.P2034T	ACH-000682	Head and Neck Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2034:2041	Mutation altering degron motif	0.7031
p.G2648R	ACH-000703	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2643:2650	Mutation altering degron motif	0.7568
p.P1449L	ACH-000714	Myeloma	CCLE	PITTT	DEG_SPOP_SBC_1	1441:1445	Mutation rewiring degron network	0.2222
p.P1449L	ACH-000714	Myeloma	CCLE	PISTT	DEG_SPOP_SBC_1	1457:1461	Mutation rewiring degron network	0.1111
p.W2122C	ACH-000727	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation rewiring degron network	0.3056
p.W2122C	ACH-000727	Lung Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2126:2133	Mutation rewiring degron network	0.2222
p.W2122C	ACH-000727	Lung Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2130:2134	Mutation rewiring degron network	0.1111
p.G1834W	ACH-000734	Liver Cancer	CCLE	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.2222
p.I1816M	ACH-000778	Head and Neck Cancer	CCLE	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation rewiring degron network	0.1111
p.T2256S	ACH-000846	Head and Neck Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2252:2259	Mutation altering degron motif	0.7116
p.I2278M	ACH-000869	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2275:2282	Mutation altering degron motif	0.7618
p.K2074M	ACH-000870	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2068:2075	Mutation altering degron motif	0.8062
p.L2232Q	ACH-000900	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2229:2236	Mutation altering degron motif	0.7765
p.T1995A	ACH-000914	Lymphoma	CCLE	PTTTPITT	DEG_SCF_FBW7_1	1988:1995	Mutation altering degron motif	0.7139
p.T1995A	ACH-000914	Lymphoma	CCLE	PITTT	DEG_SPOP_SBC_1	1992:1996	Mutation altering degron motif	0.7139
p.V2101M	ACH-000920	Leukemia	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2091:2098	Mutation rewiring degron network	0.25
p.V2101M	ACH-000920	Leukemia	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2103:2110	Mutation rewiring degron network	0.2778
p.V2101M	ACH-000920	Leukemia	CCLE	PITTT	DEG_SPOP_SBC_1	2107:2111	Mutation rewiring degron network	0.1667
p.T1913A	ACH-000946	Endometrial/Uterine Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	1907:1914	Mutation altering degron motif	0.7139
p.L2386I	ACH-000950	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2379:2386	Mutation altering degron motif	0.7174
p.L2386I	ACH-000950	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2383:2387	Mutation altering degron motif	0.7174
p.Y1992N	ACH-000957	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	1988:1995	Mutation altering degron motif	0.7059
p.Y1992N	ACH-000957	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	1992:1996	Mutation altering degron motif	0.7059
p.V2664M	ACH-000959	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation rewiring degron network	0.2778
p.V2664M	ACH-000959	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2666:2673	Mutation rewiring degron network	0.2778
p.V2664M	ACH-000959	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2659:2663	Mutation rewiring degron network	0.3056
p.S2545I	ACH-000969	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2540:2547	Mutation altering degron motif	0.7341
p.S2545I	ACH-000969	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2544:2548	Mutation altering degron motif	0.7341
p.P1663T	ACH-000971	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	1668:1672	Mutation rewiring degron network	0.1944
p.A2569V	ACH-000975	Lung Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2563:2570	Mutation altering degron motif	0.6936
p.A2569V	ACH-000975	Lung Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2567:2571	Mutation altering degron motif	0.6936
p.C2611R	ACH-000978	Endometrial/Uterine Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2609:2616	Mutation altering degron motif	0.8301
p.S1887N	ACH-000979	Prostate Cancer	CCLE	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1667
p.S1887N	ACH-000979	Prostate Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1111
p.H2192Y	ACH-000980	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2183:2190	Mutation rewiring degron network	0.2778
p.H2192Y	ACH-000980	Lung Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2195:2202	Mutation rewiring degron network	0.25
p.H2192Y	ACH-000980	Lung Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2199:2203	Mutation rewiring degron network	0.1389
p.V2722A	ACH-000982	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.25
p.V2722A	ACH-000982	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation rewiring degron network	0.2778
p.V2722A	ACH-000982	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation rewiring degron network	0.1667
p.V2722A	ACH-001345	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation rewiring degron network	0.25
p.V2722A	ACH-001345	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2724:2731	Mutation rewiring degron network	0.2778
p.V2722A	ACH-001345	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2728:2732	Mutation rewiring degron network	0.1667
p.V2744A	ACH-000996	Endometrial/Uterine Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2735:2742	Mutation rewiring degron network	0.2778
p.V2744A	ACH-000996	Endometrial/Uterine Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2747:2754	Mutation rewiring degron network	0.25
p.V2744A	ACH-000996	Endometrial/Uterine Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2751:2755	Mutation rewiring degron network	0.1389
p.A2514T	ACH-000997	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation rewiring degron network	0.2778
p.A2514T	ACH-000997	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation rewiring degron network	0.25
p.A2514T	ACH-000997	Colon/Colorectal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1389
p.T1919I	ACH-000998	Colon/Colorectal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	1919:1926	Mutation altering degron motif	0.7078
p.A2443T	ACH-000999	Colon/Colorectal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2436:2443	Mutation altering degron motif	0.7139
p.P2513S	ACH-001190	Skin Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2505:2512	Mutation rewiring degron network	0.3056
p.P2513S	ACH-001190	Skin Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2517:2524	Mutation rewiring degron network	0.2222
p.P2513S	ACH-001190	Skin Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2521:2525	Mutation rewiring degron network	0.1111
p.G2108C	ACH-001197	Lymphoma	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2103:2110	Mutation altering degron motif	0.76
p.G2108C	ACH-001197	Lymphoma	CCLE	PITTT	DEG_SPOP_SBC_1	2107:2111	Mutation altering degron motif	0.76
p.F2469L	ACH-001442	Skin Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2459:2466	Mutation rewiring degron network	0.25
p.F2469L	ACH-001442	Skin Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2471:2478	Mutation rewiring degron network	0.2778
p.F2469L	ACH-001442	Skin Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2475:2479	Mutation rewiring degron network	0.1667
p.P1826L	ACH-001521	Skin Cancer	CCLE	RATMYPD	LIG_APCC_ABBAyCdc20_2	1824:1830	Mutation altering degron motif	0.7582
p.H2786P	ACH-001524	Skin Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2781:2788	Mutation altering degron motif	0.7694
p.S1887I	ACH-001542	Head and Neck Cancer	CCLE	PTPPTT	DEG_SCF_FBW7_1	1893:1898	Mutation rewiring degron network	0.1667
p.S1887I	ACH-001542	Head and Neck Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1895:1899	Mutation rewiring degron network	0.1111
p.P2230S	ACH-001552	Skin Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2229:2236	Mutation altering degron motif	0.6752
p.S1935R	ACH-001559	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation altering degron motif	0.7427
p.P1510S	ACH-001610	Brain Cancer	CCLE	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation altering degron motif	0.6752
p.S2422F	ACH-001654	Esophageal Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2413:2420	Mutation rewiring degron network	0.2778
p.S2422F	ACH-001654	Esophageal Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2425:2432	Mutation rewiring degron network	0.25
p.S2422F	ACH-001654	Esophageal Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2429:2433	Mutation rewiring degron network	0.1389
p.P1500T	ACH-001685	Lymphoma	CCLE	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1389
p.S1501T	ACH-001685	Lymphoma	CCLE	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1667
p.S1501T	ACH-001685	Lymphoma	CCLE	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.0556
p.S1501T	ACH-001844	Bile Duct Cancer	CCLE	PITPPAS	DEG_SCF_FBW7_1	1507:1513	Mutation rewiring degron network	0.1667
p.S1501T	ACH-001844	Bile Duct Cancer	CCLE	PASTT	DEG_SPOP_SBC_1	1511:1515	Mutation rewiring degron network	0.0556
p.V2716I	ACH-001719	Ovarian Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2712:2719	Mutation altering degron motif	0.7076
p.T2659P	ACH-001991	Primary	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.7031
p.T2659P	ACH-001991	Primary	CCLE	PITTT	DEG_SPOP_SBC_1	2659:2663	Mutation altering degron motif	0.7031
p.T1758A	ACH-002139	Kidney Cancer	CCLE	PLTTT	DEG_SPOP_SBC_1	1755:1759	Mutation altering degron motif	0.7139
p.I2178T	ACH-002148	Thyroid Cancer	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.7078
p.I2178T	ACH-002148	Thyroid Cancer	CCLE	PITTT	DEG_SPOP_SBC_1	2176:2180	Mutation altering degron motif	0.7078
p.W1308L	ACH-002170	Lung Cancer	CCLE	VLSTT	DEG_SPOP_SBC_1	1294:1298	Mutation rewiring degron network	0.0556
p.W1308C	ACH-002170	Lung Cancer	CCLE	VLSTT	DEG_SPOP_SBC_1	1294:1298	Mutation rewiring degron network	0.0556
p.P1932S	ACH-002170	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	1930:1937	Mutation altering degron motif	0.5641
p.C2115Y	ACH-002173	Lung Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2114:2121	Mutation altering degron motif	0.7087
p.V2643F	ACH-002222	Leukemia	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2643:2650	Mutation altering degron motif	0.7068
p.A2620D	ACH-002251	Head and Neck Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	2620:2627	Mutation altering degron motif	0.7793
p.F2660L	ACH-002256	Leukemia	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2655:2662	Mutation altering degron motif	0.6981
p.F2660L	ACH-002256	Leukemia	CCLE	PITTT	DEG_SPOP_SBC_1	2659:2663	Mutation altering degron motif	0.6981
p.L2799F	ACH-002256	Leukemia	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2793:2800	Mutation altering degron motif	0.6981
p.L2799F	ACH-002256	Leukemia	CCLE	PITTT	DEG_SPOP_SBC_1	2797:2801	Mutation altering degron motif	0.6981
p.S2172F	ACH-002309	Sarcoma	CCLE	PTTTPITT	DEG_SCF_FBW7_1	2172:2179	Mutation altering degron motif	0.7982
p.T1430I	ACH-002659	Colon/Colorectal Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1417:1421	Mutation rewiring degron network	0.0833
p.T1430I	ACH-002659	Colon/Colorectal Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1424:1428	Mutation rewiring degron network	0.2778
p.T1430I	ACH-002659	Colon/Colorectal Cancer	CCLE	PPTTT	DEG_SPOP_SBC_1	1433:1437	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC2

UniProt ID: Q02817

Entrez ID:

Protein name: Mucin-2 (MUC-2) (Intestinal mucin-2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC2 in