Degron: VTPTPTPT
Mucin-2
MUC2
2712:2719
FBXW7
0.9958
105.4875
0.9755
0.3154
0.7019
0.0061
1.0699
0.6774
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.E2721D | TCGA-A5-A0G1 | UCEC | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.E2721D | DO42472 | UCEC | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.T2720M | DO35158 | PACA | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.3056 |
p.S2723L | DO37259 | READ | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2222 |
p.V2722A | ACH-000982 | Colon/Colorectal Cancer | CCLE | VTPTPTPT | DEG_SCF_FBW7_1 | 0.25 |
p.V2722A | ACH-001345 | Colon/Colorectal Cancer | CCLE | VTPTPTPT | DEG_SCF_FBW7_1 | 0.25 |
p.V2716I | ACH-001719 | Ovarian Cancer | CCLE | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7076 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of VTPTPTPT