Degron: VTPTPTPT
Mucin-2
MUC2
2229:2236
FBXW7
0.8816
102.025
0.9708
0.2958
0.7019
0.0071
0.91
0.6774
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.V2236F | TCGA-21-5787 | LUSC | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7068 |
p.V2234I | TCGA-A5-A0VP | UCEC | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7076 |
p.E2231K | TCGA-EE-A2MR | SKCM | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7022 |
p.L2232Q | ACH-000900 | Lung Cancer | CCLE | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7765 |
p.P2230S | ACH-001552 | Skin Cancer | CCLE | VTPTPTPT | DEG_SCF_FBW7_1 | 0.6752 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of VTPTPTPT