DegronMD

Uniprot ID: Q02817

Source protein: Mucin-2

Source gene: MUC2

Class: DEG_SCF_FBW7_1

Location: 2252:2259

E3 ligase: FBXW7

DEGRON score: 0.9339

ASA_SCORE: 104.875

COIL: 0.977

CONS_SCORE: 0.3295

DSS_SCORE: 0.7019

HELIX: 0.0062

FCONS_SCORE: 0.9505

RIG_SCORE: 0.6774

Degron related mutations and impact score

Show entries

Search:

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T2256S	ACH-000846	Head and Neck Cancer	CCLE	VTPTPTPT	DEG_SCF_FBW7_1	0.7116
p.G2258S	TCGA-FR-A726	SKCM	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	0.6993
p.R2251W	TCGA-CK-5916	COAD	TCGA	VTPTPTPT	DEG_SCF_FBW7_1	0.3056

Showing 1 to 3 of 3 entries

Previous1Next

Drug responses associated with MUC2 mutations

Show entries

Search:

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
No data available in table

Showing 0 to 0 of 0 entries

PreviousNext

All proteins holding degron of VTPTPTPT

Show entries

Search:

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q02817	Mucin-2	DEG_SCF_FBW7_1	1907:1914	VTPTPTPT	FBXW7	0.9753	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	1930:1937	VTPTPTPT	FBXW7	0.9561	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	1953:1960	VTPTPTPT	FBXW7	0.9563	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	1976:1983	VTPTPTPT	FBXW7	0.9339	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	1999:2006	VTPTPTPT	FBXW7	0.9561	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2022:2029	VTPTPTPT	FBXW7	0.9601	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2045:2052	VTPTPTPT	FBXW7	0.9339	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2068:2075	VTPTPTPT	FBXW7	0.9481	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2091:2098	VTPTPTPT	FBXW7	0.9601	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2114:2121	VTPTPTPT	FBXW7	0.9161	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2137:2144	VTPTPTPT	FBXW7	0.9563	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2160:2167	VTPTPTPT	FBXW7	0.9481	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2183:2190	VTPTPTPT	FBXW7	0.9601	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2206:2213	VTPTPTPT	FBXW7	0.9426	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2229:2236	VTPTPTPT	FBXW7	0.8816	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2252:2259	VTPTPTPT	FBXW7	0.9339	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2275:2282	VTPTPTPT	FBXW7	0.9481	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2298:2305	VTPTPTPT	FBXW7	0.9481	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2321:2328	VTPTPTPT	FBXW7	0.9161	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2344:2351	VTPTPTPT	FBXW7	0.9481	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2367:2374	VTPTPTPT	FBXW7	0.9426	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2390:2397	VTPTPTPT	FBXW7	0.9958	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2413:2420	VTPTPTPT	FBXW7	0.9601	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2436:2443	VTPTPTPT	FBXW7	0.979	More...
Q02817	Mucin-2	DEG_SCF_FBW7_1	2459:2466	VTPTPTPT	FBXW7	0.9601	More...

Showing 1 to 25 of 100 entries

Previous1 2 3 4Next

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Degron: VTPTPTPT

Degron related mutations and impact score

Drug responses associated with MUC2 mutations

All proteins holding degron of VTPTPTPT