Degron: VTPTPTPT
Mucin-2
MUC2
2344:2351
FBXW7
0.9481
102.525
0.9758
0.3745
0.7019
0.0066
0.9788
0.6774
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.A2354P | TCGA-75-5146 | LUAD | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.25 |
p.A2354P | DO25228 | LUAD | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.25 |
p.D2353N | TCGA-FX-A48G | SARC | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.D2353N | TCGA-WE-AAA0 | SKCM | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.D2353N | DO220126 | SARC | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.D2353N | DO51294 | SKCM | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.C2342Y | TCGA-NH-A5IV | COAD | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.C2342Y | DO49095 | COAD | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2778 |
p.A2344T | DO227802 | COCA | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7139 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of VTPTPTPT