Degron: VTPTPTPT
Mucin-2
MUC2
2298:2305
FBXW7
0.9481
108.525
0.9819
0.3611
0.7019
0.0056
0.9831
0.6774
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.S2303R | TCGA-19-5956 | GBM | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7427 |
p.S2303R | DO13863 | GBM | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.7427 |
p.P2309T | TCGA-86-8281 | LUAD | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2222 |
p.P2309T | DO26318 | LUAD | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.2222 |
p.R2308H | TCGA-AP-A0LM | UCEC | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.25 |
p.R2308H | DO43306 | UCEC | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.25 |
p.T2306I | TCGA-GN-A4U7 | SKCM | TCGA | VTPTPTPT | DEG_SCF_FBW7_1 | 0.3056 |
p.T2306I | DO51258 | SKCM | ICGC | VTPTPTPT | DEG_SCF_FBW7_1 | 0.3056 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of VTPTPTPT