Degron: PTTTPITT
Mucin-2
MUC2
2586:2593
FBXW7
0.9972
102.375
0.9583
0.3104
0.6965
0.0089
1.0625
0.7134
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.T2588M | TCGA-G2-AA3C | BLCA | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.6312 |
p.T2588M | DO51883 | BLCA | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.6312 |
p.T2588M | DO233145 | GACA | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.6312 |
p.V2586M | TCGA-G4-6320 | COAD | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.7208 |
p.V2586M | DO8159 | COAD | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.7208 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of PTTTPITT