Degron: PTTTPITT
Mucin-2
MUC2
2540:2547
FBXW7
0.9767
104.225
0.9668
0.3182
0.6965
0.0079
0.9032
0.7134
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.E2542K | TCGA-AA-3510 | COAD | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | TCGA-AJ-A3EL | UCEC | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | TCGA-AP-A0LM | UCEC | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | TCGA-AZ-6601 | COAD | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | TCGA-DU-8168 | LGG | TCGA | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | DO8119 | COAD | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | DO7783 | COAD | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | DO22367 | LGG | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | DO43306 | UCEC | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.E2542K | DO41542 | UCEC | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.7022 |
p.M2547L | DO233284 | GACA | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.711 |
p.M2547L | DO232846 | NACA | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.711 |
p.G2550E | DO232832 | NACA | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.25 |
p.P2549T | DO35460 | PACA | ICGC | PTTTPITT | DEG_SCF_FBW7_1 | 0.2778 |
p.S2545I | ACH-000969 | Colon/Colorectal Cancer | CCLE | PTTTPITT | DEG_SCF_FBW7_1 | 0.7341 |
Drug responses associated with MUC2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of PTTTPITT