DegronMD - Q12888(TP53BP1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P673S	TCGA-21-1079	LUSC	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.6752
p.P673S	TCGA-D9-A4Z6	SKCM	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.6752
p.P673S	TCGA-DA-A1IC	SKCM	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.6752
p.P673S	TCGA-W3-AA1W	SKCM	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.6752
p.P634L	TCGA-32-2616	GBM	TCGA	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation rewiring degron network	0.25
p.P1641S	TCGA-4Z-AA7O	BLCA	TCGA	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.6752
p.P1641S	TCGA-4Z-AA7O	BLCA	TCGA	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation altering degron motif	0.6752
p.P340S	TCGA-90-A4ED	LUSC	TCGA	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.2778
p.P340S	TCGA-RP-A693	SKCM	TCGA	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.2778
p.R639Q	TCGA-A5-A2K5	UCEC	TCGA	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation blocking phosphorylation signal	0.5556
p.R639Q	SIDM00683	Prostate Carcinoma	GDSC	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation blocking phosphorylation signal	0.5556
p.R639Q	LNCaP-Clone-FGC	prostate	COSMIC	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation blocking phosphorylation signal	0.5556
p.S640F	TCGA-AO-A03M	BRCA	TCGA	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation blocking phosphorylation signal	0.5278
p.A1646T	TCGA-AP-A059	UCEC	TCGA	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation blocking phosphorylation signal	0.6667
p.A1646T	TCGA-AP-A059	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation blocking phosphorylation signal	0.75
p.P1144L	TCGA-BF-AAP4	SKCM	TCGA	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.1944
p.L684H	TCGA-BR-8589	STAD	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.0556
p.S325F	TCGA-C5-A1MH	CESC	TCGA	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.1667
p.R78Q	TCGA-C8-A8HP	BRCA	TCGA	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation blocking phosphorylation signal	0.6111
p.E668G	TCGA-CA-6717	COAD	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.7199
p.R1632L	TCGA-D3-A2JC	SKCM	TCGA	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation rewiring degron network	0.2222
p.R1632L	TCGA-D3-A2JC	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation rewiring degron network	0.0833
p.I672F	TCGA-D9-A4Z3	SKCM	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.7415
p.S83I	TCGA-DF-A2KU	UCEC	TCGA	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.3056
p.H659Y	TCGA-EE-A2GB	SKCM	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation blocking phosphorylation signal	0.5556
p.R50Q	TCGA-EO-A22X	UCEC	TCGA	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.25
p.R50Q	TCGA-EO-A22X	UCEC	TCGA	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.0833
p.L684P	TCGA-KB-A93J	STAD	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.0556
p.A95S	TCGA-KQ-A41S	BLCA	TCGA	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.1389
p.S665L	TCGA-P3-A5Q5	HNSC	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.2778
p.E1131Q	TCGA-Q1-A73P	CESC	TCGA	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.2222
p.R1137W	TCGA-UY-A9PE	BLCA	TCGA	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.8634
p.R1137W	SIDM00142	Endometrial Carcinoma	GDSC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.8634
p.R1137W	ACH-000864	Endometrial/Uterine Cancer	CCLE	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.8634
p.R1137W	COLO-684	endometrium	COSMIC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.8634
p.G681A	TCGA-ZF-A9R7	BLCA	TCGA	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1389
p.P1636S	DO51865	BLCA	ICGC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.6752
p.A90S	DO223593	BLCA	ICGC	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.2778
p.R1132W	DO219043	BLCA	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.25
p.R1132W	DO223378	CLLE	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.25
p.R1132W	ACH-001042	Ovarian Cancer	CCLE	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.25
p.R1132W	COLO-684	endometrium	COSMIC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.25
p.G676A	DO219064	BLCA	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.2778
p.K1136Q	DO228471	BRCA	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.K1136Q	DO229013	COCA	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.K1136Q	DO229016	COCA	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.K1136Q	DO229489	LAML	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.K1136Q	DO230659	LAML	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.K1136Q	DO231140	LAML	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.K1136Q	DO229047	LICA	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6944
p.R348K	DO3822	BRCA	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.0556
p.S635F	DO2216	BRCA	ICGC	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation blocking phosphorylation signal	0.6667
p.S345C	DO51612	CESC	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.1389
p.E1126Q	DO49983	CESC	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.0833
p.E663G	DO8264	COAD	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.2222
p.S1644N	DO233885	GACA	ICGC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation altering degron motif	0.818
p.P629L	DO13462	GBM	ICGC	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation altering degron motif	0.7582
p.S660L	DO44450	HNSC	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation blocking phosphorylation signal	0.5833
p.M684I	DO48489	KIRP	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.0556
p.S95Y	DO229018	LICA	ICGC	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.1389
p.N97K	DO229031	LICA	ICGC	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.0833
p.D91E	DO229035	LICA	ICGC	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.25
p.A336D	DO229006	LICA	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.6682
p.P92T	DO229009	LICA	ICGC	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation rewiring degron network	0.2222
p.P335T	DO229008	LICA	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7031
p.N683Y	DO50755	LICA	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.0833
p.E1145K	DO218935	LUAD	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation rewiring degron network	0.1667
p.P668S	DO26846	LUSC	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.5641
p.P668S	DO37430	SKCM	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.5641
p.P668S	DO47485	SKCM	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.5641
p.P668S	DO51277	SKCM	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.5641
p.P335S	DO45482	LUSC	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.6752
p.P335S	DO51268	SKCM	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.6752
p.L339V	DO52144	PAEN	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.3056
p.G327V	DO229523	PRAD	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.2222
p.S323L	DO219871	SKCA	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation blocking phosphorylation signal	0.5556
p.R1627L	DO47578	SKCM	ICGC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation rewiring degron network	0.0833
p.I667F	DO47555	SKCM	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.7415
p.P1139L	DO219468	SKCM	ICGC	NKENP	DEG_APCC_KENBOX_2	1135:1139	Mutation altering degron motif	0.6471
p.L679H	DO47813	STAD	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1944
p.L679P	DO222336	STAD	ICGC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1944
p.G328W	DO229250	THCA	ICGC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.25
p.S78I	DO223286	UCEC	ICGC	LKENK	DEG_APCC_KENBOX_2	84:88	Mutation blocking phosphorylation signal	0.6111
p.R45Q	DO43907	UCEC	ICGC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.1111
p.R45Q	DO43907	UCEC	ICGC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.2222
p.A1641T	DO41361	UCEC	ICGC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.6028
p.A1641T	DO41361	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation altering degron motif	0.7139
p.R634Q	DO41379	UCEC	ICGC	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation rewiring degron network	0.25
p.R634Q	LNCaP-Clone-FGC	prostate	COSMIC	DSGSQAVPSP	DEG_COP1_1	622:631	Mutation rewiring degron network	0.25
p.T1652I	SIDM01283	Esophageal Carcinoma	GDSC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation substituting flanking lysine	0.1667
p.T1652I	SIDM01283	Esophageal Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation substituting flanking lysine	0.25
p.S1647A	SIDM00845	Burkitt's Lymphoma	GDSC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation blocking phosphorylation signal	0.6389
p.S1647A	SIDM00845	Burkitt's Lymphoma	GDSC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation blocking phosphorylation signal	0.7222
p.S1640F	SIDM00107	Melanoma	GDSC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.7982
p.S1640F	UACC-62	skin	COSMIC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.7982
p.H44Y	SIDM00789	Colorectal Carcinoma	GDSC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	SIDM00789	Colorectal Carcinoma	GDSC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.H44Y	SIDM00259	Neuroblastoma	GDSC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	SIDM00259	Neuroblastoma	GDSC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.H44Y	ACH-000997	Colon/Colorectal Cancer	CCLE	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	ACH-000997	Colon/Colorectal Cancer	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.H44Y	ACH-001061	Colon/Colorectal Cancer	CCLE	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	ACH-001061	Colon/Colorectal Cancer	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.H44Y	ACH-002278	Neuroblastoma	CCLE	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	ACH-002278	Neuroblastoma	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.H44Y	NB10	autonomic ganglia	COSMIC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	NB10	autonomic ganglia	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.H44Y	HCT-15	large intestine	COSMIC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.0833
p.H44Y	HCT-15	large intestine	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.25
p.T57M	SIDM00945	Colorectal Carcinoma	GDSC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation altering degron motif	0.7423
p.T57M	ACH-000895	Colon/Colorectal Cancer	CCLE	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation altering degron motif	0.7423
p.T57M	CL-34	large intestine	COSMIC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation altering degron motif	0.7423
p.S335C	SIDM00568	Gastric Carcinoma	GDSC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7541
p.S335C	SIDM00817	Kidney Carcinoma	GDSC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7541
p.S335C	SIDM01471	Chronic Myelogenous Leukemia	GDSC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7541
p.S335C	ACH-000247	Gastric Cancer	CCLE	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7541
p.S335C	ACH-000604	Leukemia	CCLE	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7541
p.S335C	OCUM-1	stomach	COSMIC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation altering degron motif	0.7541
p.E682D	SIDM00596	Endometrial Carcinoma	GDSC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1111
p.E682D	ACH-000941	Endometrial/Uterine Cancer	CCLE	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1111
p.E682D	ACH-001517	Endometrial/Uterine Cancer	CCLE	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1111
p.E682D	HEC-1	endometrium	COSMIC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.1111
p.V1638I	SIDM00375	Head and Neck Carcinoma	GDSC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.7076
p.V1638I	SKN-3	upper aerodigestive tract	COSMIC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation altering degron motif	0.7076
p.D322G	SIDM01019	Acute Myeloid Leukemia	GDSC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.0833
p.D322G	ACH-002258	Leukemia	CCLE	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.0833
p.D322G	KMOE-2	haematopoietic and lymphoid tissue	COSMIC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.0833
p.G42C	SIDM00863	Burkitt's Lymphoma	GDSC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.3056
p.G42C	ACH-000877	Lymphoma	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.3056
p.G42C	ACH-001064	Lymphoma	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.3056
p.G42C	EB2	haematopoietic and lymphoid tissue	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.3056
p.E33A	SIDM00863	Burkitt's Lymphoma	GDSC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.2778
p.E33A	ACH-000877	Lymphoma	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.2778
p.E33A	ACH-001064	Lymphoma	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.2778
p.E33A	EB2	haematopoietic and lymphoid tissue	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.2778
p.E668Q	SIDM00158	Glioblastoma	GDSC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.6744
p.E668Q	ACH-000623	Brain Cancer	CCLE	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation altering degron motif	0.6744
p.G666V	SIDM01764	Non-Small Cell Lung Carcinoma	GDSC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.3056
p.G666V	ACH-000813	Lung Cancer	CCLE	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.3056
p.V1649A	ACH-000948	Gastric Cancer	CCLE	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation rewiring degron network	0.1389
p.V1649A	ACH-000948	Gastric Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation rewiring degron network	0.2222
p.V1649A	23132-87	stomach	COSMIC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation rewiring degron network	0.1389
p.V1649A	23132-87	stomach	COSMIC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation rewiring degron network	0.2222
p.H39Y	ACH-001091	Colon/Colorectal Cancer	CCLE	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation altering degron motif	0.6118
p.H39Y	HCT-15	large intestine	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation altering degron motif	0.6118
p.H39Y	NB10	autonomic ganglia	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation altering degron motif	0.6118
p.S1635F	UACC-62	skin	COSMIC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation blocking phosphorylation signal	0.75
p.S1635F	UACC-62	skin	COSMIC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation blocking phosphorylation signal	0.6111
p.E28A	EB2	haematopoietic and lymphoid tissue	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation rewiring degron network	0.1389
p.T52M	CL-34	large intestine	COSMIC	HKENP	DEG_APCC_KENBOX_2	53:57	Mutation rewiring degron network	0.3056
p.G37C	EB2	haematopoietic and lymphoid tissue	COSMIC	DSGSHFS	DEG_SCF_TRCP1_1	35:41	Mutation altering degron motif	0.76
p.S330C	OCUM-1	stomach	COSMIC	LASTPATT	DEG_SCF_FBW7_1	331:338	Mutation rewiring degron network	0.3056
p.E677D	HEC-1	endometrium	COSMIC	IPETPCES	DEG_SCF_FBW7_1	667:674	Mutation rewiring degron network	0.25
p.V1633I	SKN-3	upper aerodigestive tract	COSMIC	PATPTAS	DEG_SCF_FBW7_1	1636:1642	Mutation rewiring degron network	0.25
p.V1633I	SKN-3	upper aerodigestive tract	COSMIC	ASSSS	DEG_SPOP_SBC_1	1641:1645	Mutation rewiring degron network	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TP53BP1

UniProt ID: Q12888

Entrez ID: 7158

Protein name: TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TP53BP1 in